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anti-BIK (BIK) Antikörper

Bezeichnung:
anti-BCL2-Interacting Killer (Apoptosis-Inducing) Antikörper (BIK)
Auf www.antikoerper-online.de finden Sie aktuell 122 BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) Antikörper von 25 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen BIK Kits (5) und BIK Proteine (5) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 147 BIK Produkte verfügbar.
Synonyme:
BIK, Biklk, BIP1, Blk, BP4, NBK, si:dkey-31f5.6
Alle Antikörper anzeigen Gen GeneID UniProt
BIK 12124  
BIK 638 Q13323
BIK 114496  

Alle Spezies anzeigen

Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-BIK (BIK) Antikörper

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anti-Mouse (Murine) BIK Antikörper:

anti-Human BIK Antikörper:

anti-Rat (Rattus) BIK Antikörper:

Alle verfügbaren anti-BIK Antikörper

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Am meisten referenzierte anti-BIK Antikörper

  1. Human Polyclonal BIK Primary Antibody für EIA, IHC (p) - ABIN358090 : Nikrad, Johnson, Puthalalath, Coultas, Adams, Kraft: The proteasome inhibitor bortezomib sensitizes cells to killing by death receptor ligand TRAIL via BH3-only proteins Bik and Bim. in Molecular cancer therapeutics 2005 (PubMed)
    Zeige alle 5 Referenzen für ABIN358090

  2. Human Monoclonal BIK Primary Antibody für IP, WB - ABIN967566 : Boyd, Gallo, Elangovan, Houghton, Malstrom, Avery, Ebb, Subramanian, Chittenden, Lutz: Bik, a novel death-inducing protein shares a distinct sequence motif with Bcl-2 family proteins and interacts with viral and cellular survival-promoting proteins. in Oncogene 1995 (PubMed)
    Zeige alle 5 Referenzen für ABIN967566

  3. Human Polyclonal BIK Primary Antibody für IHC (p), WB - ABIN388114 : Gillissen, Essmann, Graupner, Stärck, Radetzki, Dörken, Schulze-Osthoff, Daniel: Induction of cell death by the BH3-only Bcl-2 homolog Nbk/Bik is mediated by an entirely Bax-dependent mitochondrial pathway. in The EMBO journal 2003 (PubMed)
    Zeige alle 3 Referenzen für ABIN388114

  4. Human Polyclonal BIK Primary Antibody für EIA, IF - ABIN499467 : Germain, Mathai, McBride, Shore: Endoplasmic reticulum BIK initiates DRP1-regulated remodelling of mitochondrial cristae during apoptosis. in The EMBO journal 2005 (PubMed)
    Zeige alle 3 Referenzen für ABIN499467

  5. Human Polyclonal BIK Primary Antibody für IHC (p), WB - ABIN389524 : Arena, Martini, Luongo, Capelli, Larocca: Mutations of the BIK gene in human peripheral B-cell lymphomas. in Genes, chromosomes & cancer 2003 (PubMed)
    Zeige alle 2 Referenzen für ABIN389524

  6. Human Polyclonal BIK Primary Antibody für WB - ABIN223382 : Chen, Huang, Wang: Deficiency of Bim in dendritic cells contributes to overactivation of lymphocytes and autoimmunity. in Blood 2007 (PubMed)

  7. Human Polyclonal BIK Primary Antibody für IF, WB - ABIN318742 : Mathai, Germain, Shore: BH3-only BIK regulates BAX,BAK-dependent release of Ca2+ from endoplasmic reticulum stores and mitochondrial apoptosis during stress-induced cell death. in The Journal of biological chemistry 2005 (PubMed)

  8. Human Polyclonal BIK Primary Antibody für EIA, IHC (p) - ABIN356832 : Sass, Shembade, Haimerl, Lamoureux, Hashemolhosseini, Tannapfel, Tiegs: TNF pretreatment interferes with mitochondrial apoptosis in the mouse liver by A20-mediated down-regulation of Bax. in Journal of immunology (Baltimore, Md. : 1950) 2007 (PubMed)

Weitere Antikörper gegen BIK Interaktionspartner

Mouse (Murine) BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) Interaktionspartner

  1. These studies suggest a link between Bik-mediated caspase (zeige CASP3 Antikörper) activation and cleavage of viral proteins.

  2. OPN (zeige SPP1 Antikörper) induces oxidative stress via the involvement of mitochondria and NOX-4 (zeige NOX4 Antikörper). It may affect mitochondrial morphology and integrity, at least in part, via the involvement of BIK.

  3. Findings identify novel cross talk between autophagy and apoptosis, wherein targeting SQSTM1/p62 (zeige SQSTM1 Antikörper) converts cytoprotective autophagy to an inefficient form due to cargo loading failure, leading to NBK/Bik accumulation, which triggers apoptosis.

  4. Src (zeige SRC Antikörper) tyrosine kinase (zeige TYRO3 Antikörper) inhibits apoptosis through the Erk1/2 (zeige MAPK1/3 Antikörper)- dependent degradation of the death accelerator Bik.

  5. The Bik protein, even in combination with Noxa (zeige PMAIP1 Antikörper), is not a potent suppressor of c-Myc (zeige MYC Antikörper)-driven tumourigenesis or critical for chemotherapeutic drug-induced killing of Myc (zeige MYC Antikörper)-driven tumours.

  6. BIKDD, a constitutively active mutant form of proapoptotic gene, BIK, effectively induces apoptosis of breast cancer cells and synergizes with lapatinib.

  7. Blk has been mapped to chromosome 15 and overexpressed in transitional B cells of A/WySnJ mice, which demonstrate a cell-autonomous defect leading to excessive apoptosis.

  8. any function of Bik in programmed cell death and stress-induced apoptosis must overlap that of other BH3-only (zeige BBC3 Antikörper) proteins

  9. Data show that Bik and Bim (zeige BCL2L11 Antikörper) share the role of eliminating supernumerary germ cells during the first wave of spermatogenesis, a process vital for normal testicular development.

  10. Targeted expression of BikDD, a potent proapoptotic gene driven by CCKAR (zeige CCKAR Antikörper)-VISA (zeige MAVS Antikörper), exhibited antitumor effects on pancreatic cancer and prolonged survival in multiple xenograft and syngeneic mouse models of pancreatic tumors with virtually no toxicity

Human BCL2-Interacting Killer (Apoptosis-Inducing) (BIK) Interaktionspartner

  1. These studies suggest a link between Bik-mediated caspase (zeige CASP3 Antikörper) activation and cleavage of viral proteins.

  2. our data demonstrated that suppression of BIK in ER-positive MCF-7 cells prevents the cytotoxic effect of TAM (zeige CCNA1 Antikörper) and favors a more aggressive phenotype, due to the molecular change of different pathways

  3. HCV RNA replication and release were significantly suppressed in BIK-depleted cells and over-expression of the RNA-dependent RNA polymerase, NS5B, was able to induce BIK expression

  4. BikDDA, a novel mutant of Bik, showed a prolonged half-life and enhanced pro-apoptotic ability in triple-negative breast cancer cells compared with BikDD.

  5. Findings identify novel cross talk between autophagy and apoptosis, wherein targeting SQSTM1/p62 (zeige SQSTM1 Antikörper) converts cytoprotective autophagy to an inefficient form due to cargo loading failure, leading to NBK/Bik accumulation, which triggers apoptosis.

  6. Authors show that human herpesvirus 4 EBNA2 represses BIK in B-cell lymphoma-derived cell lines and that this host-virus interaction can inhibit the proapoptotic effect of transforming growth factor beta1.

  7. Data suggest BIK expression in tumor cells is not subject to direct regulation by MAP kinase (zeige MAPK1 Antikörper) signaling; BIK expression appears to be cell-cycle-dependent and increases in G1 cell-cycle arrest which results from inhibition of MAP kinase (zeige MAPK1 Antikörper) signaling.

  8. BIK/NBK gene expression may have important clinical implications and provide predictive, prognostic or therapeutic marker in breast cancer patients

  9. Src (zeige SRC Antikörper) tyrosine kinase (zeige TXK Antikörper) inhibits apoptosis through the Erk1/2 (zeige MAPK1/3 Antikörper)- dependent degradation of the death accelerator Bik.

  10. A previously undescribed indirect epigenetic regulation of BIK in FA-C lymphoblasts is mediated by DeltaNp73, an isoform of p73 (zeige TP73 Antikörper) lacking its transactivation domain that activates BIK through a proximal element in its promoter.

BIK Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins.

Alternative names and synonyms associated with BIK

  • BCL2-interacting killer (apoptosis-inducing) (BIK) Antikörper
  • BCL2-interacting killer (BIK) Antikörper
  • BCL2-interacting killer (Bik) Antikörper
  • BCL2-interacting killer (apoptosis-inducing) (Bik) Antikörper
  • BCL2-interacting killer (apoptosis-inducing) (bik) Antikörper
  • BIK Antikörper
  • Biklk Antikörper
  • BIP1 Antikörper
  • Blk Antikörper
  • BP4 Antikörper
  • NBK Antikörper
  • si:dkey-31f5.6 Antikörper

Bezeichner auf Proteinebene für BIK

BCL2-interacting killer (apoptosis-inducing) , BCL2-interacting killer , apoptosis inducer NBK , bcl-2-interacting killer , bik-like killer protein , apoptosis-inducing NBK

GENE ID SPEZIES
470232 Pan troglodytes
711479 Macaca mulatta
790946 Felis catus
12124 Mus musculus
638 Homo sapiens
114496 Rattus norvegicus
564030 Danio rerio
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