BIK Antikörper (AA 1-123)

Produktnummer ABIN3043509

Produktdetails anti-BIK Antikörper

Target: BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))

Bindungsspezifität: AA 1-123

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BIK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Bcl-2-interacting killer(BIK) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Bcl-2-interacting killer(BIK) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: BCL2-interacting killer (apoptosis-inducing)
Protein Name: Bcl-2-interacting killer

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human Bik recombinant protein (Position: M1-R123). Human Bik shares 42.3% amino acid (aa) sequence identity with mouse Bik.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu BIK

Target: BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))

Andere Bezeichnung: BIK (BIK Produkte)

Synonyme: BIK antikoerper, Biklk antikoerper, Blk antikoerper, Nbk antikoerper, BIP1 antikoerper, BP4 antikoerper, NBK antikoerper, si:dkey-31f5.6 antikoerper, BCL2 interacting killer antikoerper, BCL2-interacting killer antikoerper, BCL2-interacting killer (apoptosis-inducing) antikoerper, BIK antikoerper, Bik antikoerper, bik antikoerper

Hintergrund: Bcl-2-interacting killer is a protein that in humans is encoded by the BIK gene. This gene is mapped to 22q13.31. The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins.

Synonyms: Apoptosis inducer NBK antibody|BBC1 antibody|Bcl-2-interacting killer antibody|BCL2 interacting killer antibody|bhikhari antibody|BIK antibody|Bik-like killer protein antibody|BIK_HUMAN antibody|BIP 1 antibody|BiP1 antibody|BP 4 antibody|BP4 antibody|cb 60 antibody| NBK antibody

Gen-ID: 638

UniProt: Q13323

Pathways: Positive Regulation of Endopeptidase Activity