BIK Antikörper (AA 18-67)

Produktnummer ABIN1532228

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch BIK in WB, IHC, ELISA und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für BIK Antikörper (AA 18-67) (ABIN1532228)

Target: BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BIK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-BIK Antikörper

Bindungsspezifität: AA 18-67

Verwendungszweck: NBK Antibody

Spezifität: NBK Polyclonal Antibody detects endogenous levels of NBK protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Reinheit: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human BIK. AA range:18-67

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C/1 year

Haltbarkeit: 12 months

Details zu BIK

Target: BIK (BCL2-Interacting Killer (Apoptosis-Inducing) (BIK))

Andere Bezeichnung: BIK

Hintergrund:

Synonyms: BIK, NBK, Bcl-2-interacting killer, Apoptosis inducer NBK, BIP1, BP4

Background: The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins. [provided by RefSeq, Sep 2011],

Gene Name: BIK

Protein Name: Bcl-2-interacting killer

Molekulargewicht: 18 kDa

Gen-ID: 638

OMIM: 603392

UniProt: Q13323

Pathways: Positive Regulation of Endopeptidase Activity