anti-Ratte (Rattus) p53 Antikörper für Immunofluorescence

Recommended p53 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Tumor Protein P53 (TP53) Antikörper
  • tp53
  • p53
  • TP53
  • Tp53
  • bbl
  • bfy
  • bhy
  • p44
  • TpMs
  • BCC7
  • LFS1
  • P53
  • TRP53
  • Trp53
  • Xp53
  • brp53
  • drp53
  • etID22686.5
  • fb40d06
  • wu:fb40d06
  • zgc:111919
  • cellular tumor antigen p53
  • tumor protein p53
  • tumor supressor p53
  • p53 tumor suppressor
  • transformation related protein 53
  • transformation related protein 53, pseudogene
  • trichoplein, keratin filament binding
  • Wistar clone pR53P1 p53 pseudogene
  • CpipJ_CPIJ002758
  • TP53
  • tp53
  • P53
  • Trp53
  • Trp53-ps
  • TCHP
  • Tp53
  • p53-ps
Epitop
AA 14-389
173
128
94
84
74
71
70
62
59
55
50
49
48
47
42
38
32
31
29
28
23
22
20
20
17
16
15
15
15
15
15
14
12
11
10
10
10
9
9
8
7
7
7
7
7
7
6
6
6
6
6
5
5
5
5
5
5
5
5
5
5
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus), Yeast
2428
518
425
188
127
94
87
84
35
23
20
18
17
15
15
14
6
4
4
4
4
3
3
3
2
2
1
1
Wirt
Maus
1372
1169
7
3
1
1
1
1
Klonalität
Monoklonal
Konjugat
Dieser p53 Antikörper ist unkonjugiert
81
78
65
55
49
48
34
34
26
26
25
25
25
25
25
24
24
24
23
22
22
21
14
14
14
14
14
12
7
5
5
5
5
5
5
5
5
4
3
2
2
2
Applikation
Cytometry by Time of Flight (CyTOF), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
1931
771
750
741
650
636
434
346
315
179
72
41
32
31
23
17
17
15
13
9
9
4
4
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
Hersteller
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Produktnummer ABIN152249
Preis und Verfügbarkeit auf Anfrage.
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
12.14905 ABIN2705092 IC IF IHC WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal
12.14905 ABIN2957704 IC IF IHC WB Rabbit N-Term Anmelden zum Anzeigen Polyclonal
12.14905 ABIN2707674 IC IF IP IHC WB Rabbit N-Term, pSer15 Anmelden zum Anzeigen Polyclonal
12.14905 ABIN2705091 IC IF IP IHC WB Rabbit C-Term, pSer315 Anmelden zum Anzeigen Polyclonal
12.14905 ABIN2705093 IC IF IHC WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal
12.14905 ABIN2705097 IC IF IHC WB Rabbit C-Term Anmelden zum Anzeigen Polyclonal
12.14905 ABIN2705096 IC IF IHC WB Rabbit C-Term, acLys386 Anmelden zum Anzeigen Polyclonal
12.14905 ABIN1532374 IF IHC ELISA WB Rabbit IgG AA 10-59 Anmelden zum Anzeigen Polyclonal
12.14905 ABIN1535547 IF IHC ELISA WB Rabbit IgG AA 283-332 Anmelden zum Anzeigen Polyclonal
12.14905 ABIN1535549 IF IHC ELISA WB Rabbit IgG AA 344-393 Anmelden zum Anzeigen Polyclonal
12.14905 ABIN1535527 IF ELISA WB Rabbit IgG AA 283-332, acLys317 Anmelden zum Anzeigen Polyclonal
12.14905 ABIN1535528 IF IHC ELISA Rabbit IgG AA 344-393, acLys381 Anmelden zum Anzeigen Polyclonal
12.14905 ABIN1870674 IF WB Rabbit IgG pSer15 Anmelden zum Anzeigen Polyclonal
1 ABIN4342743 ICC IF IHC IHC (p) IP WB Rabbit pSer15 Anmelden zum Anzeigen Polyclonal 2
1 ABIN967409 FACS IF IP WB Mouse IgG2b Anmelden zum Anzeigen PAb 122 5
1 ABIN3181875 ELISA IF IHC Rabbit IgG acLys381 Anmelden zum Anzeigen Polyclonal
1 ABIN3186272 ELISA IF IHC WB Rabbit IgG Tyr191 Anmelden zum Anzeigen Polyclonal
1 ABIN3186273 ELISA IF IHC WB Rabbit IgG C-Term Anmelden zum Anzeigen Polyclonal
1 ABIN3182104 ELISA IF IHC IP WB Rabbit IgG pSer15 Anmelden zum Anzeigen Polyclonal
1 ABIN3186283 ELISA IF IHC WB Rabbit IgG Tyr21 Anmelden zum Anzeigen Polyclonal

General

Antigen Tumor Protein P53 (TP53) Antikörper
Epitop AA 14-389
(173), (128), (94), (84), (74), (71), (70), (62), (59), (55), (50), (49), (48), (47), (42), (38), (32), (31), (29), (28), (23), (22), (20), (20), (17), (16), (15), (15), (15), (15), (15), (14), (12), (11), (10), (10), (10), (9), (9), (8), (7), (7), (7), (7), (7), (7), (6), (6), (6), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus), Yeast
(2428), (518), (425), (188), (127), (94), (87), (84), (35), (23), (20), (18), (17), (15), (15), (14), (6), (4), (4), (4), (4), (3), (3), (3), (2), (2), (1), (1)
Wirt Maus
(1372), (1169), (7), (3), (1), (1), (1), (1)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser p53 Antikörper ist unkonjugiert
(81), (78), (65), (55), (49), (48), (34), (34), (26), (26), (25), (25), (25), (25), (25), (24), (24), (24), (23), (22), (22), (21), (14), (14), (14), (14), (14), (12), (7), (5), (5), (5), (5), (5), (5), (5), (5), (4), (3), (2), (2), (2)
Applikation Cytometry by Time of Flight (CyTOF), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
(1931), (771), (750), (741), (650), (636), (434), (346), (315), (179), (72), (41), (32), (31), (23), (17), (17), (15), (13), (9), (9), (4), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 20 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-p53 Antikörper

Target Details p53 Anwendungsinformationen Handhabung Referenzen für anti-p53 Antikörper (ABIN152249) Bilder
Spezifität This monoclonal recognizes both mutant forms and wild-type human p53 under denaturing conditions.
Keine Kreuzreaktivität Xenopus laevis
Reinigung Protein G purified
Immunogen Gel-purified p53-beta-galactosidase fusion protein containing murine p53 from aa 14-389 (derived from pSV53C cDNA clone).
Klon PAb 240
Isotyp IgG1 kappa

Target Details p53

Produktdetails anti-p53 Antikörper Anwendungsinformationen Handhabung Referenzen für anti-p53 Antikörper (ABIN152249) Bilder zurück nach oben
Antigen
Andere Bezeichnung p53 (TP53 Antibody Abstract)
Hintergrund Gene Symbol: TP53
Gen-ID 7157
Forschungsgebiet DNA/RNA, Cell Cycle, Transcription Factors, Apoptosis/Necrosis, Cancer
Pathways p53 Signalweg, MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagie

Anwendungsinformationen

Produktdetails anti-p53 Antikörper Target Details p53 Handhabung Referenzen für anti-p53 Antikörper (ABIN152249) Bilder zurück nach oben
Applikationshinweise Western Blot 1:1000-1:2000, Flow Cytometry 1:10-1:1000, ELISA 1:100-1:2000, Immunohistochemistry 1:250-1:500, Immunocytochemistry/Immunofluorescence 5 μg/mL, Immunoprecipitation 10 μg/mg, Immunohistochemistry-Paraffin 1:250-1:500, Immunohistochemistry-Frozen, CyTOF-readyAntigen retrieval with IHC-P is not essential but may optimise staining. In IP this antibody reacts with only mutant p53 protein under non-denaturing conditions. Use in Immunocytochemistry/immunofluorescence reported in scientific literature (PMID 1394225) Use in Immunohistochemistry-Frozen reported in various pieces of scientific literature.
Kommentare

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-p53 Antikörper Target Details p53 Anwendungsinformationen Referenzen für anti-p53 Antikörper (ABIN152249) Bilder zurück nach oben
Format Liquid
Konzentration 1.0 mg/mL
Buffer PBS
Buffer contains: 0.02 % Sodium Azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid freeze-thaw cycles
Lagerung 4 °C,-20 °C
Informationen zur Lagerung Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Referenzen für anti-p53 Antikörper (ABIN152249)

Produktdetails anti-p53 Antikörper Target Details p53 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Graham, Minasyan, Lomova, Cass, Balanis, Friedman, Chan, Zhao, Delgado, Go, Beck, Hurtz, Ng, Qiao, Ten Hoeve, Palaskas, Wu, Müschen, Multani, Port, Larson, Schultz, Braas, Christofk, Mellinghoff et al.: "Recurrent patterns of DNA copy number alterations in tumors reflect metabolic selection pressures. ..." in: Molecular systems biology, Vol. 13, Issue 2, pp. 914, 2017 Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Mouse (Murine)).

Shi, Ma, Zhou, Fu: "Renal Protective Effects of 17β-Estradiol on Mice with Acute Aristolochic Acid Nephropathy." in: Molecules (Basel, Switzerland), Vol. 21, Issue 10, 2016

Ge, Pettan-Brewer, Morton, Carter, Fatemi, Rabinovitch, Ladiges: "Mitochondrial catalase suppresses naturally occurring lung cancer in old mice." in: Pathobiology of aging & age related diseases, Vol. 5, pp. 28776, 2015 (Probematerial (Species): Mouse (Murine)). Weitere Details: Immunohistochemistry

Biswas, Mitchell, Johnson: "E2F1 responds to ultraviolet radiation by directly stimulating DNA repair and suppressing carcinogenesis." in: Cancer research, Vol. 74, Issue 12, pp. 3369-77, 2014 (Probematerial (Species): Mouse (Murine)). Weitere Details: Immunohistochemistry (Paraffin-embedded Sections)

Lange, Bedford, Reh, Wittschieben, Carbajal, Kusewitt, DiGiovanni, Wood: "Dual role for mammalian DNA polymerase ζ in maintaining genome stability and proliferative responses." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 8, pp. E687-96, 2013 (Probematerial (Species): Mouse (Murine)). Weitere Details: Immunohistochemistry (Paraffin-embedded Sections)

Jensen, Factor, Fantozzi, Helin, Huh, Thorgeirsson: "Reduced hepatic tumor incidence in cyclin G1-deficient mice." in: Hepatology (Baltimore, Md.), Vol. 37, Issue 4, pp. 862-70, 2003 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting

Asher, Lotem, Cohen, Sachs, Shaul: "Regulation of p53 stability and p53-dependent apoptosis by NADH quinone oxidoreductase 1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 3, pp. 1188-93, 2001 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting

Jones, Turner, McIlwrath, Brown, Dive: "Cisplatin- and paclitaxel-induced apoptosis of ovarian carcinoma cells and the relationship between bax and bak up-regulation and the functional status of p53." in: Molecular pharmacology, Vol. 53, Issue 5, pp. 819-26, 1998 (Probematerial (Species): Human). Weitere Details: Immunoprecipitation

Blagosklonny, Toretsky, Bohen, Neckers: "Mutant conformation of p53 translated in vitro or in vivo requires functional HSP90." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 16, pp. 8379-83, 1996 (Probematerial (Species): Yeast). Weitere Details: Immunoprecipitation

Bargonetti, Manfredi, Chen, Marshak, Prives: "A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein." in: Genes & development, Vol. 7, Issue 12B, pp. 2565-74, 1994 (Probematerial (Species): Human). Weitere Details: Western Blotting

Rubio, von Deimling, Yandell, Wiestler, Gusella, Louis: "Accumulation of wild type p53 protein in human astrocytomas." in: Cancer research, Vol. 53, Issue 15, pp. 3465-7, 1993 (Probematerial (Species): Human). Weitere Details: Immunohistochemistry (Frozen Sections)

Halazonetis, Davis, Kandil: "Wild-type p53 adopts a 'mutant'-like conformation when bound to DNA." in: The EMBO journal, Vol. 12, Issue 3, pp. 1021-8, 1993 (Probematerial (Species): Human). Weitere Details: Western Blotting,Immunoprecipitation

Eccles, Brett, Lessells, Gruber, Lane, Steel, Leonard: "Overexpression of the p53 protein and allele loss at 17p13 in ovarian carcinoma." in: British journal of cancer, Vol. 65, Issue 1, pp. 40-4, 1992 (Probematerial (Species): Human). Weitere Details: Immunohistochemistry (Frozen Sections)

Somers, Merrick, Lopez, Incognito, Schechter, Casey: "Frequent p53 mutations in head and neck cancer." in: Cancer research, Vol. 52, Issue 21, pp. 5997-6000, 1992 (Probematerial (Species): Human). Weitere Details: Immunocytochemistry,Immunofluorescence

Remvikos, Tominaga, Hammel, Laurent-Puig, Salmon, Dutrillaux, Thomas: "Increased p53 protein content of colorectal tumours correlates with poor survival." in: British journal of cancer, Vol. 66, Issue 4, pp. 758-64, 1992 (Probematerial (Species): Human). Weitere Details: ELISA,Flow Cytometry

Cunningham, Lust, Schaid, Bren, Carpenter, Rizza, Kovach, Thibodeau: "Expression of p53 and 17p allelic loss in colorectal carcinoma." in: Cancer research, Vol. 52, Issue 7, pp. 1974-80, 1992 (Probematerial (Species): Human). Weitere Details: Immunohistochemistry

Farrell, Allan, Shanahan, Vousden, Crook: "p53 is frequently mutated in Burkitt's lymphoma cell lines." in: The EMBO journal, Vol. 10, Issue 10, pp. 2879-87, 1991 Weitere Details: Immunoprecipitation

Martinez, Georgoff, Martinez, Levine: "Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein." in: Genes & development, Vol. 5, Issue 2, pp. 151-9, 1991 (Probematerial (Species): Rat (Rattus)). Weitere Details: Immunocytochemistry,Immunofluorescence

Davidoff, Humphrey, Iglehart, Marks: "Genetic basis for p53 overexpression in human breast cancer." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 11, pp. 5006-10, 1991 (Probematerial (Species): Human). Weitere Details: Immunohistochemistry

Gannon, Greaves, Iggo, Lane: "Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form." in: The EMBO journal, Vol. 9, Issue 5, pp. 1595-602, 1990 Weitere Details: Western Blotting,Immunoprecipitation,ELISA,Immunohistochemistry

Bilder

Produktdetails anti-p53 Antikörper Target Details p53 Anwendungsinformationen Handhabung Referenzen für anti-p53 Antikörper (ABIN152249) zurück nach oben
Bilder des Herstellers
 image for anti-Tumor Protein P53 (TP53) (AA 14-389) antibody (ABIN152249) Flow (Intracellular): p53 Antibody (PAb 240) [ABIN152249] - An intracellular stain wa...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Tumor Protein P53 (TP53) (AA 14-389) antibody (ABIN152249) Immunohistochemistry-Paraffin: p53 Antibody (PAb 240) [ABIN152249] - p53 was detected...
Immunofluorescence (IF) image for anti-Tumor Protein P53 (TP53) (AA 14-389) antibody (ABIN152249) Immunocytochemistry/Immunofluorescence: p53 Antibody (PAb 240) [ABIN152249] - HeLa ce...
Western Blotting (WB) image for anti-Tumor Protein P53 (TP53) (AA 14-389) antibody (ABIN152249) Western Blot: p53 Antibody (PAb 240) [ABIN152249] - WB analysis of p53 in MCF7 and He...