anti-Human p53 Antikörper für Enzyme Immunoassay

Recommended p53 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Tumor Protein P53 (TP53) Antikörper
  • tp53
  • p53
  • TP53
  • Tp53
  • bbl
  • bfy
  • bhy
  • p44
  • TpMs
  • BCC7
  • LFS1
  • P53
  • TRP53
  • Trp53
  • Xp53
  • brp53
  • drp53
  • etID22686.5
  • fb40d06
  • wu:fb40d06
  • zgc:111919
  • cellular tumor antigen p53
  • tumor protein p53
  • tumor supressor p53
  • p53 tumor suppressor
  • transformation related protein 53
  • transformation related protein 53, pseudogene
  • trichoplein, keratin filament binding
  • Wistar clone pR53P1 p53 pseudogene
  • CpipJ_CPIJ002758
  • TP53
  • tp53
  • P53
  • Trp53
  • Trp53-ps
  • TCHP
  • Tp53
  • p53-ps
Epitop
Ser315
170
118
84
83
69
65
55
55
54
53
49
47
46
45
40
32
31
31
25
23
22
22
20
18
17
16
15
15
15
15
15
14
11
10
10
9
9
9
8
8
7
7
7
7
6
6
6
6
5
5
5
5
5
5
5
5
5
5
5
5
5
4
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human
2329
514
419
186
127
94
85
82
34
23
20
18
17
16
15
14
6
4
4
4
4
3
3
3
2
2
1
1
Wirt
Kaninchen
1321
1113
7
3
3
1
1
1
Klonalität
Polyklonal
Konjugat
Dieser p53 Antikörper ist unkonjugiert
78
76
63
53
45
44
30
30
25
25
25
24
24
24
24
23
23
23
21
20
19
18
14
14
14
14
14
12
7
5
5
5
5
5
5
5
5
4
3
2
2
2
Applikation
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
1856
746
718
715
614
596
424
340
300
179
72
41
32
31
18
17
15
14
13
9
9
4
4
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
Hersteller
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Bilder

Produktnummer ABIN358189
407,00 €
Zzgl. Versandkosten 20,00 € und MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN358423 EIA Rabbit Ig pThr55 Anmelden zum Anzeigen Polyclonal 5
1 ABIN120054 EIA IHC (fro) IHC (p) IP WB Mouse IgG2a AA 20-25 Anmelden zum Anzeigen DO-1 3
1 ABIN358757 EIA WB Rabbit Ig C-Term Anmelden zum Anzeigen Polyclonal 5
1 ABIN111971 EIA IHC (fro) IF IHC (p) IP WB Mouse IgG2a AA 16-25 Anmelden zum Anzeigen BP53-12 8
1 ABIN264401 EIA IP WB Mouse IgG1 AA 16-25 Anmelden zum Anzeigen X77 2
1 ABIN320175 EIA IHC (fro) IHC (p) IP WB Mouse IgG2a AA 20-25 Anmelden zum Anzeigen DO-1 4
1 ABIN5552130 EIA IHC (p) WB Rabbit Ig Fraction pThr18 Anmelden zum Anzeigen Polyclonal
1 ABIN5552129 EIA IHC (p) WB Rabbit Ig Fraction pSer20 Anmelden zum Anzeigen Polyclonal
1 ABIN264449 EIA IHC (fro) IP WB Mouse IgG2b AA 371-380 Anmelden zum Anzeigen HR231
1 ABIN5552146 EIA IHC (p) Rabbit Ig Fraction Ser315 Anmelden zum Anzeigen Polyclonal
1 ABIN452450 EIA IHC (fro) IF IHC (p) IP WB Mouse IgG2a AA 20-31 Anmelden zum Anzeigen Bp53-11 8
1 ABIN126847 EIA WB Mouse IgG1 phosphorylated Anmelden zum Anzeigen 9F4
1 ABIN271769 EIA WB Rabbit Anmelden zum Anzeigen Polyclonal
1 ABIN5550996 EIA FACS IHC (fro) IHC (p) IP RIA WB Mouse IgG1 AA 46-53 Anmelden zum Anzeigen Pab 1801

anti-p53 Antikörper für Enzyme Immunoassay mit den meisten Publikationen

Ähnliche anti-p53 Antikörper

Applikation / Reaktivität Human
Affinity Purification (AP) 2 Antikörper
Blocking Antibody (Inhibition) 1 Antikörper
Cellular Assay (CA) 1 Antikörper
Chromatin Immunoprecipitation (ChIP) 16 Antikörper
Cytometry by Time of Flight (CyTOF) 18 Antikörper
Dot Blot (DB) 27 Antikörper
ELISA 695 Antikörper
ELISA (Capture) 2 Antikörper
ELISA (Detection) 2 Antikörper
Enzyme Immunoassay (EIA) 15 Antikörper
Flow Cytometry (FACS) 587 Antikörper
Gel Shift (GS) 3 Antikörper
Immunoassay (IA) 1 Antikörper
Immunochromatography (IC) 41 Antikörper
Immunocytochemistry (ICC) 322 Antikörper
Immunodiffusion (ID) 15 Antikörper
Immunofluorescence (IF) 593 Antikörper
Immunofluorescence (Cultured Cells) (IF (cc)) 13 Antikörper
Immunofluorescence (fixed cells) (IF/ICC) 28 Antikörper

General

Antigen Tumor Protein P53 (TP53) Antikörper
Epitop Ser315
(170), (118), (84), (83), (69), (65), (55), (55), (54), (53), (49), (47), (46), (45), (40), (32), (31), (31), (25), (23), (22), (22), (20), (18), (17), (16), (15), (15), (15), (15), (15), (14), (11), (10), (10), (9), (9), (9), (8), (8), (7), (7), (7), (7), (6), (6), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human
(2329), (514), (419), (186), (127), (94), (85), (82), (34), (23), (20), (18), (17), (16), (15), (14), (6), (4), (4), (4), (4), (3), (3), (3), (2), (2), (1), (1)
Wirt Kaninchen
(1321), (1113), (7), (3), (3), (1), (1), (1)
Klonalität
Polyklonal
Konjugat Dieser p53 Antikörper ist unkonjugiert
(78), (76), (63), (53), (45), (44), (30), (30), (25), (25), (25), (24), (24), (24), (24), (23), (23), (23), (21), (20), (19), (18), (14), (14), (14), (14), (14), (12), (7), (5), (5), (5), (5), (5), (5), (5), (5), (4), (3), (2), (2), (2)
Applikation Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(1856), (746), (718), (715), (614), (596), (424), (340), (300), (179), (72), (41), (32), (31), (18), (17), (15), (14), (13), (9), (9), (4), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 5 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-p53 Antikörper

Target Details p53 Anwendungsinformationen Handhabung ProductDetails: References for anti-p53 antibody (ABIN358189) Bilder
Spezifität This antibody detects p53 pSer315.
Reinigung Protein G Affinity Chromatography. Then, the antibody fraction is Peptide Affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Immunogen KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Ser315 of Human p53.
Isotyp Ig

Target Details p53

Produktdetails anti-p53 Antikörper Anwendungsinformationen Handhabung ProductDetails: References for anti-p53 antibody (ABIN358189) Bilder zurück nach oben
Antigen
Andere Bezeichnung p53 (TP53) (TP53 Antibody Abstract)
Hintergrund Tumor protein p53, a nuclear protein, plays an essential role in the regulation of cell cycle, specifically in the transition from G0 to G1. It is found in very low levels in normal cells, however, in a variety of transformed cell lines, it is expressed in high amounts, and believed to contribute to transformation and malignancy. p53 is a DNA-binding protein containing DNA-binding, oligomerization and transcription activation domains. It is postulated to bind as a tetramer to a p53-binding site and activate expression of downstream genes that inhibit growth and/or invasion, and thus function as a tumor suppressor. Mutants of p53 that frequently occur in a number of different human cancers fail to bind the consensus DNA binding site, and hence cause the loss of tumor suppressor activity. Alterations of the TP53 gene occur not only as somatic mutations in human malignancies, but also as germline mutations in some cancer-prone families with Li-Fraumeni syndrome.Synonyms: Cellular tumor antigen p53, NY-CO-13, Phosphoprotein p53, Tumor suppressor p53
Gen-ID 7157, 9606
UniProt P04637
Pathways p53 Signalweg, MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagie

Anwendungsinformationen

Produktdetails anti-p53 Antikörper Target Details p53 Handhabung ProductDetails: References for anti-p53 antibody (ABIN358189) Bilder zurück nach oben
Applikationshinweise ELISA: 1/1,000. Dot Blot: 1/500. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-p53 Antikörper Target Details p53 Anwendungsinformationen ProductDetails: References for anti-p53 antibody (ABIN358189) Bilder zurück nach oben
Format Liquid
Konzentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) Sodium Azide as preservative
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freezing and thawing.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

ProductDetails: References for anti-p53 antibody (ABIN358189)

Produktdetails anti-p53 Antikörper Target Details p53 Anwendungsinformationen Handhabung Bilder zurück nach oben
Allgemeine Veröffentlichungen

Seemann, Hainaut: "Roles of thioredoxin reductase 1 and APE/Ref-1 in the control of basal p53 stability and activity." in: Oncogene, Vol. 24, Issue 24, pp. 3853-63, 2005

Mann, Hainaut: "Aminothiol WR1065 induces differential gene expression in the presence of wild-type p53." in: Oncogene, Vol. 24, Issue 24, pp. 3964-75, 2005

Garden, Morrison: "The multiple roles of p53 in the pathogenesis of HIV associated dementia." in: Biochemical and biophysical research communications, Vol. 331, Issue 3, pp. 799-809, 2005

Castedo, Perfettini, Piacentini, Kroemer: "p53-A pro-apoptotic signal transducer involved in AIDS." in: Biochemical and biophysical research communications, Vol. 331, Issue 3, pp. 701-6, 2005

Duensing, Duensing: "Guilt by association? p53 and the development of aneuploidy in cancer." in: Biochemical and biophysical research communications, Vol. 331, Issue 3, pp. 694-700, 2005

Bilder

Produktdetails anti-p53 Antikörper Target Details p53 Anwendungsinformationen Handhabung ProductDetails: References for anti-p53 antibody (ABIN358189) zurück nach oben
Bilder des Herstellers
 image for anti-p53 Antikörper (Tumor Protein P53) (Ser315) (ABIN358189) anti-Tumor Protein P53 (TP53) (Ser315) antibody
 image for anti-p53 Antikörper (Tumor Protein P53) (Ser315) (ABIN358189) anti-Tumor Protein P53 (TP53) (Ser315) antibody (Image 2)