anti-Human p53 Antikörper für Cytometry by Time of Flight

Recommended p53 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Tumor Protein P53 (TP53) Antikörper
  • tp53
  • p53
  • TP53
  • Tp53
  • bbl
  • bfy
  • bhy
  • p44
  • TpMs
  • BCC7
  • LFS1
  • P53
  • TRP53
  • Trp53
  • Xp53
  • brp53
  • drp53
  • etID22686.5
  • fb40d06
  • wu:fb40d06
  • zgc:111919
  • cellular tumor antigen p53
  • tumor protein p53
  • tumor supressor p53
  • p53 tumor suppressor
  • transformation related protein 53
  • transformation related protein 53, pseudogene
  • trichoplein, keratin filament binding
  • Wistar clone pR53P1 p53 pseudogene
  • CpipJ_CPIJ002758
  • TP53
  • tp53
  • P53
  • Trp53
  • Trp53-ps
  • TCHP
  • Tp53
  • p53-ps
Epitop
AA 14-389
175
125
91
84
74
71
70
62
59
55
50
49
48
45
42
38
32
31
28
23
22
20
17
16
15
15
15
15
15
15
14
11
10
10
10
9
9
8
8
7
7
7
7
6
6
6
6
6
5
5
5
5
5
5
5
5
5
5
4
4
4
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus), Yeast
2387
516
423
186
127
94
85
82
35
23
20
18
17
15
15
14
6
4
4
4
4
3
3
3
2
2
1
1
Wirt
Maus
1365
1133
7
3
3
1
1
1
Klonalität
Monoklonal
Konjugat
Dieser p53 Antikörper ist unkonjugiert
81
78
65
54
46
45
31
31
26
25
25
25
25
25
25
24
24
24
22
20
19
18
14
14
14
14
14
12
7
5
5
5
5
5
5
5
5
4
3
2
2
2
Applikation
Cytometry by Time of Flight (CyTOF), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
1915
767
746
732
625
614
431
345
313
179
72
41
32
31
20
17
17
15
13
9
9
4
4
3
3
3
2
2
1
1
1
1
1
1
1
1
1
1
Hersteller
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Bilder

Produktnummer ABIN152249
341,00 €
Zzgl. Versandkosten 20,00 € und MWSt
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN4900612 CyTOF FACS WB Mouse IgG1 pSer15 Anmelden zum Anzeigen 261352
1 ABIN4900613 CyTOF FACS ICC Mouse IgG1 pSer15 Anmelden zum Anzeigen 261366
1 ABIN4342741 CyTOF ELISA FACS ICC IF IHC IHC (fro) IHC (p) IP WB Mouse IgG1 kappa AA 14-389 Anmelden zum Anzeigen PAb 240
1 ABIN4342795 CyTOF ELISA FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG2a AA 16-25, N-Term Anmelden zum Anzeigen BP53-12
1 ABIN4342796 CyTOF ELISA FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG2a AA 16-25, N-Term Anmelden zum Anzeigen BP53-12
1 ABIN4342823 CyTOF ELISA FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG2b kappa AA 37-45 Anmelden zum Anzeigen SPM590
1 ABIN4342824 CyTOF ELISA FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG2b kappa AA 37-45 Anmelden zum Anzeigen SPM590
1 ABIN4342827 CyTOF FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG AA 20-25 Anmelden zum Anzeigen BP53-12-DO-7
1 ABIN4342828 CyTOF FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG AA 20-25 Anmelden zum Anzeigen BP53-12-DO-7
1 ABIN4342829 CyTOF ELISA FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG2b kappa AA 37-45 Anmelden zum Anzeigen DO-7
1 ABIN4342830 CyTOF ELISA FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG2b kappa AA 37-45 Anmelden zum Anzeigen DO-7
1 ABIN4342831 CyTOF ELISA FACS ICC IF IHC (fro) IP WB Mouse IgG2b kappa AA 370-378, C-Term Anmelden zum Anzeigen PAb122
1 ABIN4342832 CyTOF ELISA FACS ICC IF IHC (fro) IP WB Mouse IgG2b kappa AA 370-378, C-Term Anmelden zum Anzeigen PAb122
1 ABIN4900470 CyTOF FACS Mouse IgG2b AA 7-393 Anmelden zum Anzeigen 184727
1 ABIN4342833 CyTOF ELISA FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG2a AA 20-25 Anmelden zum Anzeigen SPM589
1 ABIN4342834 CyTOF ELISA FACS ICC IF IHC (fro) IHC (p) IP WB Mouse IgG2a AA 20-25 Anmelden zum Anzeigen SPM589
1 ABIN4342933 CyTOF FACS IF IHC (p) WB Mouse IgG2a Anmelden zum Anzeigen TRP-816
1 ABIN4342934 CyTOF FACS IF IHC (p) WB Mouse IgG2a Anmelden zum Anzeigen TRP-816
1 ABIN4962885 CyTOF FACS ICC IF IHC (p) WB Rabbit IgG kappa Anmelden zum Anzeigen TP53-1799R
1 ABIN4962886 CyTOF FACS ICC IF IHC (p) WB Rabbit IgG kappa Anmelden zum Anzeigen TP53-1799R

General

Antigen Tumor Protein P53 (TP53) Antikörper
Epitop AA 14-389
(175), (125), (91), (84), (74), (71), (70), (62), (59), (55), (50), (49), (48), (45), (42), (38), (32), (31), (28), (23), (22), (20), (17), (16), (15), (15), (15), (15), (15), (15), (14), (11), (10), (10), (10), (9), (9), (8), (8), (7), (7), (7), (7), (6), (6), (6), (6), (6), (5), (5), (5), (5), (5), (5), (5), (5), (5), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus), Yeast
(2387), (516), (423), (186), (127), (94), (85), (82), (35), (23), (20), (18), (17), (15), (15), (14), (6), (4), (4), (4), (4), (3), (3), (3), (2), (2), (1), (1)
Wirt Maus
(1365), (1133), (7), (3), (3), (1), (1), (1)
Klonalität (Klon)
Monoklonal   ( )
Konjugat Dieser p53 Antikörper ist unkonjugiert
(81), (78), (65), (54), (46), (45), (31), (31), (26), (25), (25), (25), (25), (25), (25), (24), (24), (24), (22), (20), (19), (18), (14), (14), (14), (14), (14), (12), (7), (5), (5), (5), (5), (5), (5), (5), (5), (4), (3), (2), (2), (2)
Applikation Cytometry by Time of Flight (CyTOF), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
(1915), (767), (746), (732), (625), (614), (431), (345), (313), (179), (72), (41), (32), (31), (20), (17), (17), (15), (13), (9), (9), (4), (4), (3), (3), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Pubmed 20 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-p53 Antikörper

Target Details p53 Anwendungsinformationen Handhabung ProductDetails: References for anti-p53 antibody (ABIN152249) Bilder
Spezifität This monoclonal recognizes both mutant forms and wild-type human p53 under denaturing conditions.
Keine Kreuzreaktivität Xenopus laevis
Reinigung Protein G purified
Immunogen Gel-purified p53-beta-galactosidase fusion protein containing murine p53 from aa 14-389 (derived from pSV53C cDNA clone).
Klon PAb 240
Isotyp IgG1 kappa

Target Details p53

Produktdetails anti-p53 Antikörper Anwendungsinformationen Handhabung ProductDetails: References for anti-p53 antibody (ABIN152249) Bilder zurück nach oben
Antigen
Andere Bezeichnung p53 (TP53 Antibody Abstract)
Hintergrund Gene Symbol: TP53
Gen-ID 7157
Forschungsgebiet DNA/RNA, Cell Cycle, Transcription Factors, Apoptosis/Necrosis, Cancer
Pathways p53 Signalweg, MAPK Signalweg, PI3K-Akt Signalweg, Apoptose, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagie

Anwendungsinformationen

Produktdetails anti-p53 Antikörper Target Details p53 Handhabung ProductDetails: References for anti-p53 antibody (ABIN152249) Bilder zurück nach oben
Applikationshinweise Western Blot 1:1000-1:2000, Flow Cytometry 1:10-1:1000, ELISA 1:100-1:2000, Immunohistochemistry 1:250-1:500, Immunocytochemistry/Immunofluorescence 5 μg/mL, Immunoprecipitation 10 μg/mg, Immunohistochemistry-Paraffin 1:250-1:500, Immunohistochemistry-Frozen, CyTOF-readyAntigen retrieval with IHC-P is not essential but may optimise staining. In IP this antibody reacts with only mutant p53 protein under non-denaturing conditions. Use in Immunocytochemistry/immunofluorescence reported in scientific literature (PMID 1394225) Use in Immunohistochemistry-Frozen reported in various pieces of scientific literature.
Kommentare

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-p53 Antikörper Target Details p53 Anwendungsinformationen ProductDetails: References for anti-p53 antibody (ABIN152249) Bilder zurück nach oben
Format Liquid
Konzentration 1.0 mg/mL
Buffer PBS
Buffer contains: 0.02 % Sodium Azide
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid freeze-thaw cycles
Lagerung 4 °C,-20 °C
Informationen zur Lagerung Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

ProductDetails: References for anti-p53 antibody (ABIN152249)

Produktdetails anti-p53 Antikörper Target Details p53 Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Graham, Minasyan, Lomova, Cass, Balanis, Friedman, Chan, Zhao, Delgado, Go, Beck, Hurtz, Ng, Qiao, Ten Hoeve, Palaskas, Wu, Müschen, Multani, Port, Larson, Schultz, Braas, Christofk, Mellinghoff et al.: "Recurrent patterns of DNA copy number alterations in tumors reflect metabolic selection pressures. ..." in: Molecular systems biology, Vol. 13, Issue 2, pp. 914, 2017 Von den Autoren verwendete Methode: Western Blotting (WB) (Probematerial (Species): Mouse (Murine)).

Shi, Ma, Zhou, Fu: "Renal Protective Effects of 17β-Estradiol on Mice with Acute Aristolochic Acid Nephropathy." in: Molecules (Basel, Switzerland), Vol. 21, Issue 10, 2016

Ge, Pettan-Brewer, Morton, Carter, Fatemi, Rabinovitch, Ladiges: "Mitochondrial catalase suppresses naturally occurring lung cancer in old mice." in: Pathobiology of aging & age related diseases, Vol. 5, pp. 28776, 2015 (Probematerial (Species): Mouse (Murine)). Weitere Details: Immunohistochemistry

Biswas, Mitchell, Johnson: "E2F1 responds to ultraviolet radiation by directly stimulating DNA repair and suppressing carcinogenesis." in: Cancer research, Vol. 74, Issue 12, pp. 3369-77, 2014 (Probematerial (Species): Mouse (Murine)). Weitere Details: Immunohistochemistry (Paraffin-embedded Sections)

Lange, Bedford, Reh, Wittschieben, Carbajal, Kusewitt, DiGiovanni, Wood: "Dual role for mammalian DNA polymerase ζ in maintaining genome stability and proliferative responses." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 8, pp. E687-96, 2013 (Probematerial (Species): Mouse (Murine)). Weitere Details: Immunohistochemistry (Paraffin-embedded Sections)

Jensen, Factor, Fantozzi, Helin, Huh, Thorgeirsson: "Reduced hepatic tumor incidence in cyclin G1-deficient mice." in: Hepatology (Baltimore, Md.), Vol. 37, Issue 4, pp. 862-70, 2003 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting

Asher, Lotem, Cohen, Sachs, Shaul: "Regulation of p53 stability and p53-dependent apoptosis by NADH quinone oxidoreductase 1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 3, pp. 1188-93, 2001 (Probematerial (Species): Mouse (Murine)). Weitere Details: Western Blotting

Jones, Turner, McIlwrath, Brown, Dive: "Cisplatin- and paclitaxel-induced apoptosis of ovarian carcinoma cells and the relationship between bax and bak up-regulation and the functional status of p53." in: Molecular pharmacology, Vol. 53, Issue 5, pp. 819-26, 1998 (Probematerial (Species): Human). Weitere Details: Immunoprecipitation

Blagosklonny, Toretsky, Bohen, Neckers: "Mutant conformation of p53 translated in vitro or in vivo requires functional HSP90." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 16, pp. 8379-83, 1996 (Probematerial (Species): Yeast). Weitere Details: Immunoprecipitation

Bargonetti, Manfredi, Chen, Marshak, Prives: "A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein." in: Genes & development, Vol. 7, Issue 12B, pp. 2565-74, 1994 (Probematerial (Species): Human). Weitere Details: Western Blotting

Rubio, von Deimling, Yandell, Wiestler, Gusella, Louis: "Accumulation of wild type p53 protein in human astrocytomas." in: Cancer research, Vol. 53, Issue 15, pp. 3465-7, 1993 (Probematerial (Species): Human). Weitere Details: Immunohistochemistry (Frozen Sections)

Halazonetis, Davis, Kandil: "Wild-type p53 adopts a 'mutant'-like conformation when bound to DNA." in: The EMBO journal, Vol. 12, Issue 3, pp. 1021-8, 1993 (Probematerial (Species): Human). Weitere Details: Western Blotting,Immunoprecipitation

Eccles, Brett, Lessells, Gruber, Lane, Steel, Leonard: "Overexpression of the p53 protein and allele loss at 17p13 in ovarian carcinoma." in: British journal of cancer, Vol. 65, Issue 1, pp. 40-4, 1992 (Probematerial (Species): Human). Weitere Details: Immunohistochemistry (Frozen Sections)

Somers, Merrick, Lopez, Incognito, Schechter, Casey: "Frequent p53 mutations in head and neck cancer." in: Cancer research, Vol. 52, Issue 21, pp. 5997-6000, 1992 (Probematerial (Species): Human). Weitere Details: Immunocytochemistry,Immunofluorescence

Remvikos, Tominaga, Hammel, Laurent-Puig, Salmon, Dutrillaux, Thomas: "Increased p53 protein content of colorectal tumours correlates with poor survival." in: British journal of cancer, Vol. 66, Issue 4, pp. 758-64, 1992 (Probematerial (Species): Human). Weitere Details: ELISA,Flow Cytometry

Cunningham, Lust, Schaid, Bren, Carpenter, Rizza, Kovach, Thibodeau: "Expression of p53 and 17p allelic loss in colorectal carcinoma." in: Cancer research, Vol. 52, Issue 7, pp. 1974-80, 1992 (Probematerial (Species): Human). Weitere Details: Immunohistochemistry

Farrell, Allan, Shanahan, Vousden, Crook: "p53 is frequently mutated in Burkitt's lymphoma cell lines." in: The EMBO journal, Vol. 10, Issue 10, pp. 2879-87, 1991 Weitere Details: Immunoprecipitation

Martinez, Georgoff, Martinez, Levine: "Cellular localization and cell cycle regulation by a temperature-sensitive p53 protein." in: Genes & development, Vol. 5, Issue 2, pp. 151-9, 1991 (Probematerial (Species): Rat (Rattus)). Weitere Details: Immunocytochemistry,Immunofluorescence

Davidoff, Humphrey, Iglehart, Marks: "Genetic basis for p53 overexpression in human breast cancer." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, Issue 11, pp. 5006-10, 1991 (Probematerial (Species): Human). Weitere Details: Immunohistochemistry

Gannon, Greaves, Iggo, Lane: "Activating mutations in p53 produce a common conformational effect. A monoclonal antibody specific for the mutant form." in: The EMBO journal, Vol. 9, Issue 5, pp. 1595-602, 1990 Weitere Details: Western Blotting,Immunoprecipitation,ELISA,Immunohistochemistry

Bilder

Produktdetails anti-p53 Antikörper Target Details p53 Anwendungsinformationen Handhabung ProductDetails: References for anti-p53 antibody (ABIN152249) zurück nach oben
Bilder des Herstellers
 image for anti-Tumor Protein P53 (TP53) (AA 14-389) antibody (ABIN152249) Flow (Intracellular): p53 Antibody (PAb 240) [ABIN152249] - An intracellular stain wa...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-Tumor Protein P53 (TP53) (AA 14-389) antibody (ABIN152249) Immunohistochemistry-Paraffin: p53 Antibody (PAb 240) [ABIN152249] - p53 was detected...
Immunofluorescence (IF) image for anti-Tumor Protein P53 (TP53) (AA 14-389) antibody (ABIN152249) Immunocytochemistry/Immunofluorescence: p53 Antibody (PAb 240) [ABIN152249] - HeLa ce...
Western Blotting (WB) image for anti-Tumor Protein P53 (TP53) (AA 14-389) antibody (ABIN152249) Western Blot: p53 Antibody (PAb 240) [ABIN152249] - WB analysis of p53 in MCF7 and He...