BAX Proteine (BAX)

BCL2-Associated X Protein Proteine (BAX)
Auf finden Sie aktuell 19 BCL2-Associated X Protein (BAX) Proteine von 9 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen BAX Antikörper (529) und BAX Kits (68) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 651 BAX Produkte verfügbar.
BAX, bax-A, BAX-ALPHA, BCL2L4, fj16e01, wu:fc50b10, wu:fj16e01, xBax, xlbax
alle Proteine anzeigen Gen GeneID UniProt
BAX 581 Q07812
BAX 12028 Q07813
Ratte BAX BAX 24887  

Weitere Synonyme anzeigen

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Am meisten referenzierte BAX Proteine

  1. Human BAX Protein expressed in Wheat germ - ABIN1346448 : Bras, Yuste, Roué, Barbier, Sancho, Virely, Rubio, Baudet, Esquerda, Merle-Béral, Sarfati, Susin: Drp1 mediates caspase-independent type III cell death in normal and leukemic cells. in Molecular and cellular biology 2007 (PubMed)

Weitere Proteine zu BAX Interaktionspartnern

Zebrafish BCL2-Associated X Protein (BAX) Interaktionspartner

  1. These results suggest a role for mitochondrial p53 (zeige TP53 Proteine) activity in promoting hair cell death due to aminoglycosides, likely upstream of Bax and Bcl2 (zeige BCL2 Proteine).

Xenopus laevis BCL2-Associated X Protein (BAX) Interaktionspartner

  1. xlbax is a regulator of muscle fiber death in the regressing tail during metamorphosis.

Cow (Bovine) BCL2-Associated X Protein (BAX) Interaktionspartner

  1. BoHV-5 replication apparently modulates BCL-2 (zeige BCL2 Proteine) expression and gene transcription, enhancing production of virus progeny, but does not increase Bax expression.

  2. It was concluded that the Fas (zeige FAS Proteine)-FasL (zeige FASL Proteine) signaling pathway was involved in regulation of bovine oocyte apoptosis, perhaps related to B (zeige TDO2 Proteine) cell lymphoma/leukemia-2 associated X upregulation.

  3. apoptosis-inducing factor (zeige AIFM1 Proteine) was expressed in luminal alveolar cells and, in concert with a change in bax protein to bcl-2 (zeige BCL2 Proteine) protein ratio, might contribute to signalling of a change in the dynamic balance of the cell population as lactation progresses

  4. mRNA expression of Bax, Bcl-2 (zeige BCL2 Proteine), caspase-3 (zeige CASP3 Proteine) and-7 cannot be used as a reliable apoptosis detection method.

  5. The effect of culture conditions on expression of heat shock protein 70 (zeige HSP70 Proteine) and Bax protein in bovine blastocysts is reported.

Human BCL2-Associated X Protein (BAX) Interaktionspartner

  1. Although TP53 (zeige TP53 Proteine) and BAX immunoreactivity levels were associated with some clinicopathological parameters of the patients, the expression of EP300 (zeige EP300 Proteine), TP53 (zeige TP53 Proteine) and BAX did not reveal any prognostic significance in ccRCC

  2. Cells expressing mitoCERT import ceramides into mitochondria and undergo Bax-dependent apoptosis.

  3. Recent studies that combine experiments in yeast and in mammalian cells have shown the unexpected effect of the anti-apoptotic protein Bcl-xL (zeige BCL2L1 Proteine) on the priming of Bax. As demonstrated with the BH3-mimetic molecule ABT-737, this property of Bcl-xL (zeige BCL2L1 Proteine), and of Bcl-2 (zeige BCL2 Proteine), is crucial to elaborate about how apoptosis could be reactivated in tumoral cells.

  4. Results support the hypothesis that the mitochondrion-specific lipid cardiolipin functions as a first contact site for Bax during its translocation to the mitochondrial outer membrane in the onset of apoptosis. In addition, dye leakage assays revealed that different oxidized phospholipids species in the mitochondrial outer membrane-mimicking vesicles can have opposing effects on Bax pore formation.

  5. These results not only establish Bok (zeige BOK Proteine) as a Bak (zeige BAK1 Proteine)- and Bax-independent apoptosis inducer, but also suggest a potential impact of Bok (zeige BOK Proteine) expression in ovarian cancer therapy.

  6. The substitution of proline 168 for alanine favors Bax oligomerization.

  7. Data show that the increased acetylation of Ku autoantigen 70kDa (Ku70 (zeige XRCC6 Proteine)) in sirtuin 6 (zeige SIRT6 Proteine) protein (SIRT6 (zeige SIRT6 Proteine))-depleted cells disrupt its interaction with Bax apoptosis regulator protein (Bax), which finally resulted in Bax mitochondrial translocalization.

  8. Rhaponticum carthamoides extracts from transformed and normal roots increased the ratio of Bax/Bcl-2 (zeige BCL2 Proteine) proteins and increased TP53 (zeige TP53 Proteine) levels to reduce glioma cell proliferation.

  9. these results indicate that EVA71 infection directly impacts the mitochondrial apoptotic pathway by modulating the recruitment and activation of Bax.

  10. the present study demonstrated that DAPK (zeige DAPK1 Proteine) contributed to the Hcyinduced endothelial apoptosis via modulation of Bcl2 (zeige BCL2 Proteine)/Bax expression levels and activation of caspase 3 (zeige CASP3 Proteine)

Mouse (Murine) BCL2-Associated X Protein (BAX) Interaktionspartner

  1. Postnatal synaptic rearrangement needed for acquisition of skilled behaviors requires the activity-dependent, non-apoptotic Bax/Bak (zeige BAK1 Proteine)-caspase (zeige CASP3 Proteine) signaling cascade. Adult Bax/Bak (zeige BAK1 Proteine) mutant mice exhibit aberrant co-activation of antagonistic muscle pairs and skilled grasping deficits but normal reaching and retrieval behaviors.

  2. Study found that emphysema occurred in ku70(-/-) mice at the age of three-months old, and that Bax deficiency was able to suppress it. These results suggest that Bax-mediated apoptosis induces emphysema in ku70(-/-) mice.

  3. The polyglutamine embedded in the ER membrane was observed at the same time as Bax insertion. These results demonstrated that the ER membrane may be a target of polyglutamine, which triggers cell death through Bax.

  4. These results suggest that Bax mediates beta-cell apoptosis in Pdx1 (zeige PDX1 Proteine)-deficient diabetes.

  5. Bim (zeige BCL2L11 Proteine) and Puma (zeige BBC3 Proteine) overlapped apoptosis only partially during physiological apoptotic stage and they were present in non-apoptotic parts of the follicles.

  6. This study demonstated that Bax KO mice show Hyperactivity and depression.

  7. The influence of chronic ethanol consumption on the expression of the Bdnf (zeige BDNF Proteine), Bax, Bcl-xL (zeige BCL2L1 Proteine), and CASP3 (zeige CASP3 Proteine) genes was studied in the brain structures of B6-1473C (C/C) and B6-1473G (G/G) mice that had been obtained on the base of the C57BL/6 strain.

  8. These data indicate that the rapid and robust microglial activation and PIF (zeige DCD Proteine) expression observed in situ following acute EtOH exposure is largely driven indirectly by BAX-dependent apoptotic cell death, rather than directly by the EtOH.

  9. lipid profile in the absence of the proapoptotic proteins BAX and BAK (zeige BAK1 Proteine) in mouse embryonic fibroblasts

  10. despite its role in Bax inhibition, Bcl-xL (zeige BCL2L1 Proteine) also primes mitochondria to permeabilization and cytochrome c (zeige CYCS Proteine) release.

Pig (Porcine) BCL2-Associated X Protein (BAX) Interaktionspartner

  1. Bid (zeige BID Proteine) and Bax are signal transduction factors in granulosa cells and play proapoptotic roles.

  2. The data demonstrate that severe hypocapnia results in increased Bax expression, DNA fragmentation, and membrane lipid peroxidation in mitochondria of cerebral cortical neurons of newborn piglets, and may result in apoptotic cell death.

Guinea Pig BCL2-Associated X Protein (BAX) Interaktionspartner

  1. bcl-2 (zeige BCL2 Proteine) and bax were expressed strongly in denervated guinea-pig facial muscle. [bcl-2 (zeige BCL2 Proteine); bax]

Goat BCL2-Associated X Protein (BAX) Interaktionspartner

  1. goat oocytes based on G6PDH (zeige G6PD Proteine)-activity through the BCB test improves their developmental competence, increases intracellular GSH content, and affects the expression of the apoptosis-related genes9 Bax and Bcl-2 (zeige BCL2 Proteine) ).

Rabbit BCL2-Associated X Protein (BAX) Interaktionspartner

  1. The content of Bax protein in the cardiomyocyte cytoplasm decreased, thus indicating that the mitochondrial pathway was not involved in the realization of the apoptotic program in a model of ventricular overload.

  2. These results indicate that RI-PostC can ameliorate myocardial ischemia-reperfusion injury and increase the Bcl-2/Bax ratio through a mechanism involving protein kinase C.

  3. Cinobufagin can remarkably inhibit the proliferation and induce the apoptosis of lens epithelial cells by increasing expression of bax and decreasing expression of bcl2 (zeige BCL2 Proteine).

  4. Elevated local temperature of the testis buried in the inguinal pocket increases the apoptosis of spermatogenic cells, and the spermatogenic cell apoptosis is highly correlated with the decreased expression of Bcl-2 (zeige BCL2 Proteine) and increased expression of Bax.

  5. In this study evidence is provided that exogenous PGF2alpha differentially modulates luteal expression of BCL2-associated X protein (BAX) transcripts and protein depending on luteal stage.

BAX Protein Überblick

Protein Überblick

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.

Alternative names and synonyms associated with BAX

  • bcl2-associated X protein, a (baxa)
  • BCL2-associated X protein (bax)
  • BCL2-associated X protein (BAX)
  • BCL2-associated X protein (Bax)
  • Bcl2-associated X protein (Bax)
  • BCL2-associated X protein (LOC100355675)
  • BAX Protein
  • bax-A Protein
  • BAX-ALPHA Protein
  • BCL2L4 Protein
  • fj16e01 Protein
  • wu:fc50b10 Protein
  • wu:fj16e01 Protein
  • xBax Protein
  • xlbax Protein

Bezeichner auf Proteinebene für BAX

zBax1 , bax zeta , apoptosis regulator BAX , BCL2-associated X protein , BCL2-associated X protein omega , BCL2-associated X protein transcript variant delta2 , bcl-2-like protein 4 , bcl2-L-4 , BCL2-associated protein

58081 Danio rerio
373637 Xenopus laevis
394793 Xenopus (Silurana) tropicalis
493837 Felis catus
747093 Pan troglodytes
785708 Bos taurus
581 Homo sapiens
12028 Mus musculus
24887 Rattus norvegicus
403523 Canis lupus familiaris
280730 Bos taurus
396633 Sus scrofa
100730890 Cavia porcellus
100846984 Capra hircus
443059 Ovis aries
100355675 Oryctolagus cuniculus
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