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BAX Protein (BCL2-Associated X Protein) (Myc-DYKDDDDK Tag)

BAX Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2715165
$1,112.40
Zzgl. Versandkosten $45.00 und $20.00 Trockeneis
20 μg
Lieferung in 11 Werktagen
  • Target Alle BAX Proteine anzeigen
    BAX (BCL2-Associated X Protein (BAX))
    Protein-Typ
    Recombinant
    Spezies
    • 6
    • 5
    • 2
    • 2
    • 2
    Human
    Quelle
    • 13
    • 2
    • 2
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses BAX Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human Bax (transcript variant alpha) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    BAX (BCL2-Associated X Protein (BAX))
    Andere Bezeichnung
    Bax (BAX Produkte)
    Synonyme
    BAX-ALPHA, bax-A, xBax, xlbax, BAX, bax, fj16e01, wu:fc50b10, wu:fj16e01, BCL2L4, BCL2 associated X, apoptosis regulator, BCL2-associated X protein L homeolog, BCL2-associated X protein, bcl2-associated X protein, a, BAX, bax.L, bax, baxa, Bax
    Hintergrund
    The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene.
    Molekulargewicht
    21 kDa
    NCBI Accession
    NP_620116
    Pathways
    p53 Signalweg, PI3K-Akt Signalweg, Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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