Retinoic Acid Receptor gamma Proteine (RARG)

Bezeichnung:
Retinoic Acid Receptor, gamma Proteine (RARG)
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Synonyme:
AI385767, nr1b3, RARC, RARD, RARG, RARgamma2
alle Proteine anzeigen Gen GeneID UniProt
RARG 5916 P13631
RARG 19411 P18911
Ratte RARG RARG 685072  

Weitere Synonyme anzeigen

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Human Retinoic Acid Receptor, gamma (RARG) Interaktionspartner

  1. Loss of RARG expression is associated with Colorectal Tumorigenesis and Metastasis.

  2. A nonsynonymous variant in RARG is highly associated with anthracycline-induced cardiotoxicity in childhood cancers.

  3. deregulation of the retinoid/rexinoid signaling pathway has a major role and may represent a potential therapeutic target for NUP98 (zeige NUP98 Proteine)-RARG-mediated transformation

  4. The current status of knowledge indicates that there might be inter- or overlapping actions between PPARg (zeige PPARG Proteine) and RARs (zeige RARS Proteine), and there might be an association of PPARg (zeige PPARG Proteine)/RARs (zeige RARS Proteine)(RARa (zeige RARA Proteine), RARb (zeige RARB Proteine), and RARg) with renal diseases

  5. RARgamma in concert with ATRA regulates protein levels of CDK1 (zeige CDK1 Proteine) and its subcellular localization.

  6. RARG plays an important role in the proliferation, metastasis, and chemoresistance of cholangiocarcinoma through simultaneous activation of the Akt (zeige AKT1 Proteine)/NF-kappaB (zeige NFKB1 Proteine) and Wnt (zeige WNT2 Proteine)/beta-catenin (zeige CTNNB1 Proteine) pathways.

  7. Evidence that the retinoic acid receptor gamma plays a major role in the regulation of the human prostatic transglutaminase gene.

  8. findings demonstrate that signaling through RARs (zeige RARS Proteine) has critical roles in molecular reprogramming and that the synergistic interaction between Rarg and Lrh1 (zeige NR5A2 Proteine) directs reprogramming toward ground-state pluripotency

  9. results suggest that a RARgamma-dependent functional crosstalk is present between the retinoic acid and BMP2 (zeige BMP2 Proteine) signaling to induce osteogenic transdifferentiation in myoblastic C2C12 cells

  10. One variant in the RARA (zeige RARA Proteine) gene (rs12051734), three variants in the RARB (zeige RARB Proteine) gene (rs6799734, rs12630816, rs17016462), and one variant in the RARG gene (rs3741434) were found to be statistically significant at p < 0.05 as risk factors for meningomyelocele.

Mouse (Murine) Retinoic Acid Receptor, gamma (RARG) Interaktionspartner

  1. the reprogramming of epiblast stem cells into embryonic stem cell-like cells also requires low levels of retinoic acid (RA), which can modulate Wnt (zeige WNT2 Proteine) signalling through physical interactions of RARs (zeige RARS Proteine) with beta-catenin (zeige CTNNB1 Proteine).

  2. Data show that retinoic acid receptor gamma (RARgamma)-proto-oncogene protein c-fos (c-Fos)-PPARgamma2 (PPARgamma2 (zeige PPARG Proteine)) signaling rather than reactive oxygen species generation is critical for all-trans retinoic acid (ATRA)-inhibited adipocyte differentiation.

  3. RARgamma plays key roles in the differentiation competence of NGN3 (zeige NEUROG3 Proteine)+ cells in response to retinoic acid during mouse spermatogenesis.

  4. The results indicate a physiological role for RARgamma as a negative regulator of osteoclastogenesis in vivo and in vitro, and reveal distinct influences of RARalpha (zeige RARA Proteine) and RARgamma in bone structure regulation.

  5. this study shows that the combination of Rarg and Nr5a2 (zeige NR5A2 Proteine) rapidly promote the iN cell maturation within 1 week and greatly facilitate the conversion with neuronal purities of approximately 50% and yields of >130%.

  6. Data indicate that all three retinoic acid receptor (zeige RARA Proteine) isoforms RARalha, RARbeta (zeige RARB Proteine) and RARgamma are expressed in naive CD8 (zeige CD8A Proteine)+ T cells, as well as CD8 (zeige CD8A Proteine)+ T cells activated for 48 or 72 h.

  7. erythroid-specific RAR (zeige RARA Proteine) function is dispensable for erythropoiesis and RARgamma plays an erythroid extrinsic role in erythropoiesis.

  8. RARG plays an important role in the proliferation, metastasis, and chemoresistance of cholangiocarcinoma through simultaneous activation of the Akt (zeige AKT1 Proteine)/NF-kappaB (zeige NFKB1 Proteine) and Wnt (zeige WNT2 Proteine)/beta-catenin (zeige CTNNB1 Proteine) pathways.

  9. Data indicate that male germ cell specific miR (zeige MLXIP Proteine)-34c might be pivotal in embryonic stem cells (ESCs (zeige NR2E3 Proteine)) differentiation into male germ cells through its target retinoic acid receptor gamma (RARg).

  10. RARG cell-autonomously transduces, in undifferentiated spermatogonia of adult testes, a RA signal critical for spermatogenesis.

Retinoic Acid Receptor gamma (RARG) Protein Überblick

Protein Überblick

This gene encodes a retinoic acid receptor that belongs to the nuclear hormone receptor family. Retinoic acid receptors (RARs) act as ligand-dependent transcriptional regulators. When bound to ligands, RARs activate transcription by binding as heterodimers to the retinoic acid response elements (RARE) found in the promoter regions of the target genes. In their unbound form, RARs repress transcription of their target genes. RARs are involved in various biological processes, including limb bud development, skeletal growth, and matrix homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with Retinoic Acid Receptor gamma (RARG)

  • retinoic acid receptor, gamma (RARG)
  • retinoic acid receptor, gamma (Rarg)
  • retinoic acid receptor, gamma (rarg)
  • AI385767 Protein
  • nr1b3 Protein
  • RARC Protein
  • RARD Protein
  • RARG Protein
  • RARgamma2 Protein

Bezeichner auf Proteinebene für RARG

retinoic acid receptor, gamma , retinoic acid receptor gamma-like , retinoic acid receptor gamma , RAR-gamma , nuclear receptor subfamily 1 group B member 3 , retinoic acid nuclear receptor gamma variant 1 , retinoic acid nuclear receptor gamma variant 2 , RAR gamma 2 , RAR-gamma 2.1 , rar gamma , retinoic acid receptor gamma isoform 2.1

GENE ID SPEZIES
451935 Pan troglodytes
486508 Canis lupus familiaris
699532 Macaca mulatta
100403219 Callithrix jacchus
100474471 Ailuropoda melanoleuca
5916 Homo sapiens
19411 Mus musculus
540425 Bos taurus
685072 Rattus norvegicus
397983 Xenopus laevis
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