anti-LFNG (LFNG) Antikörper

Bezeichnung:
anti-LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase Antikörper (LFNG)
Auf www.antikoerper-online.de finden Sie aktuell 62 LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG) Antikörper von 14 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen LFNG Kits (15) und LFNG Proteine (10) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 91 LFNG Produkte verfügbar.
Synonyme:
AW061165, id:ibd2614, id:ibd5029, id:ibd5138, l-fng, SCDO3, wu:fc69h02, wu:fi34c01

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anti-Human LFNG Antikörper:

anti-Mouse (Murine) LFNG Antikörper:

anti-Rat (Rattus) LFNG Antikörper:

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Am meisten referenzierte anti-LFNG Antikörper

  1. Human Polyclonal LFNG Primary Antibody für IHC (p), WB - ABIN953163 : Dunwoodie: Mutation of the fucose-specific beta1,3 N-acetylglucosaminyltransferase LFNG results in abnormal formation of the spine. in Biochimica et biophysica acta 2009 (PubMed)
    Zeige alle 2 Referenzen für 953163

  2. Cow (Bovine) Polyclonal LFNG Primary Antibody für WB - ABIN2782070 : Sparrow, Chapman, Wouters, Whittock, Ellard, Fatkin, Turnpenny, Kusumi, Sillence, Dunwoodie: Mutation of the LUNATIC FRINGE gene in humans causes spondylocostal dysostosis with a severe vertebral phenotype. in American journal of human genetics 2005 (PubMed)

  3. Human Polyclonal LFNG Primary Antibody für ELISA, WB - ABIN1534692 : Johnston, Rauskolb, Wilson, Prabhakaran, Irvine, Vogt: A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway. in Development (Cambridge, England) 1997 (PubMed)

Weitere Antikörper gegen LFNG Interaktionspartner

Human LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG) Interaktionspartner

  1. a potent tumor-suppressive function for Lfng

  2. TGFBR2 (zeige TGFBR2 Antikörper) signaling can affect Notch1 (zeige NOTCH1 Antikörper) glycosylation via regulation of glycosyltransferase (zeige GTDC2 Antikörper) LFNG expression and provide a first mechanistic example for altered glycosylation in microsatellite instability colorectal tumor cells.

  3. LFNG expression correlates with expansion of cancer stem cell populations and NKX3.1 (zeige NKX3-1 Antikörper) expression in human prostate cancer.

  4. Reduced LFNG expression facilitates JAG/NOTCH (zeige NOTCH1 Antikörper) luminal progenitor signaling and cooperates with MET/CAVEOLIN basal-type signaling to promote basal-like breast cancer.

  5. Mutation of the LFNG gene causes spondylocostal dysostosis with a severe vertebral phenotype, reinforcing the hypothesis that proper regulation of the Notch (zeige NOTCH1 Antikörper) signaling pathway is an absolute requirement for the correct patterning of the axial skeleton.

Mouse (Murine) LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG) Interaktionspartner

  1. a potent tumor-suppressive function for Lfng

  2. Fringe modifications at EGF8 and EGF12 enhanced Notch1 binding to and activation from Delta-like 1, while modifications at EGF6 and EGF36 (added by Manic and Lunatic but not Radical) inhibited Notch1 activation from Jagged1.

  3. LFNG protein may have context-dependent effects on Notch (zeige NOTCH1 Antikörper) activity; somitogenesis is disrupted by a novel dominant allele of Lfng

  4. Lfng expression and activity is normal in mice whose Lfng is lengthened by 10 kb, and no effects on segmentation are evident.

  5. suggest that modulation of the Notch (zeige NOTCH1 Antikörper) signaling by Lfng affects the clock period during development

  6. STAT5 (zeige STAT5A Antikörper)-dependent amplification of Notch (zeige NOTCH1 Antikörper)-modifying Lfng augments Th2 response via Dll4 (zeige DLL4 Antikörper) and is critical for amplifying viral exacerbation during allergic airway disease.

  7. The repressive effect of Lfng against Notch (zeige NOTCH1 Antikörper) activities in neighbouring cells can sufficiently explain the synchronization in vivo.

  8. Intriguing changes are observed in the cranio-caudal (zeige CAD Antikörper) borders of multifidus muscle in mutant Dll3 (zeige DLL3 Antikörper) and Lfng models of idiopathic scoliosis.

  9. Reduced LFNG expression facilitates JAG/NOTCH (zeige NOTCH1 Antikörper) luminal progenitor signaling and cooperates with MET/CAVEOLIN basal-type signaling to promote basal-like breast cancer.

  10. the presence of Gal (zeige GAL Antikörper) on O-fucose glycans differentially affects DLL1 (zeige DLL1 Antikörper)-induced NOTCH (zeige NOTCH1 Antikörper) signaling modulated by LFNG versus MFNG (zeige MFNG Antikörper)

Zebrafish LFNG O-Fucosylpeptide 3-beta-N-Acetylglucosaminyltransferase (LFNG) Interaktionspartner

  1. lfng regulates delta-notch (zeige NOTCH1 Antikörper) induction of hypochord.

  2. The sequence and embryonic expression of lfng were studied.

  3. Lfng acts in a feedback loop downstream of proneural genes.

LFNG Antigen-Profil

Beschreibung des Gens

This gene is a member of the fringe gene family which also includes radical and manic fringe genes. They all encode evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, fringe proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. This gene product is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150). Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with LFNG

  • LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (LFNG) Antikörper
  • lunatic fringe (LOC100218383) Antikörper
  • LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (Lfng) Antikörper
  • lunatic fringe (lfng) Antikörper
  • lunatic fringe homolog (lfng) Antikörper
  • AW061165 Antikörper
  • id:ibd2614 Antikörper
  • id:ibd5029 Antikörper
  • id:ibd5138 Antikörper
  • l-fng Antikörper
  • SCDO3 Antikörper
  • wu:fc69h02 Antikörper
  • wu:fi34c01 Antikörper

Bezeichner auf Proteinebene für LFNG

lunatic fringe , beta-1,3-N-acetylglucosaminyltransferase lunatic fringe , O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase , lunatic fringe gene homolog , lunatic fringe homolog

GENE ID SPEZIES
100012518 Monodelphis domestica
100218383 Taeniopygia guttata
3955 Homo sapiens
516209 Bos taurus
16848 Mus musculus
170905 Rattus norvegicus
395790 Gallus gallus
101112372 Ovis aries
397855 Xenopus laevis
30158 Danio rerio
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