anti-MAP3K7 (MAP3K7) Antikörper

Auf www.antikoerper-online.de finden Sie aktuell 177 Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) Antikörper von 16 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MAP3K7 Kits (10) und MAP3K7 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 214 MAP3K7 Produkte verfügbar.
Synonyme:
B430101B05, C87327, MEKK7, si:ch211-225h9.1, TAK1, TGF1a, zgc:110612
Alle Antikörper anzeigen Gen GeneID UniProt
MAP3K7 313121 P0C8E4
MAP3K7 6885 O43318
MAP3K7 26409 Q62073

Meistgesuchte Reaktivitäten zu anti-MAP3K7 (MAP3K7) Antikörper

anti-Rat (Rattus) MAP3K7 Antikörper:

anti-Human MAP3K7 Antikörper:

anti-Mouse (Murine) MAP3K7 Antikörper:

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Weitere Antikörper gegen MAP3K7 Interaktionspartner

Human Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) Interaktionspartner

  1. TAK1 regulates Nrf2 (zeige GABPA Antikörper) through modulation of Keap-p62/SQSTM1 (zeige SQSTM1 Antikörper) interaction. This regulation is important for homeostatic antioxidant protection in the intestinal epithelium.

  2. Overexpression of TAK1 was strongly associated with positive lymph node metastasis in pancreatic ductal adenocarcinoma.

  3. dysregulation of the TAK1 complex produces a close phenocopy of Frontometaphyseal Dysplasia caused by FLNA (zeige FLNA Antikörper) mutations; furthermore, the pathogenesis of some of the filaminopathies caused by FLNA (zeige FLNA Antikörper) mutations might be mediated by misregulation of signaling coordinated through the TAK1 signaling complex

  4. although TAK1 is located at the crossroad of inflammation, immunity, and cancer, this study reports MAP3K7 mutations in a developmental disorder affecting mainly cartilage, bone, and heart

  5. This study suggests that aberrant activity of TAK1 impairs autophagy and subsequently leads to alterations in the vitality of retinal pigment epithelial cells.

  6. TAK1 may be an important factor involved in the pathogenesis of thyroid cancer, and targeted down-regulation of TAK1 may improve the prognosis of patients with thyroid cancer.

  7. Loss of MAP3K7 are associated with esophageal squamous cell carcinoma.

  8. This paper highlights that targeting the BMP and TGFbeta (zeige TGFB1 Antikörper) type I and type II receptors causes a downregulation of XIAP (zeige XIAP Antikörper), TAK1, and Id1 (zeige ID1 Antikörper) leading to cell death of lung cancer cells.

  9. Polyubiquitination of Transforming Growth Factor beta-activated Kinase 1 (TAK1) at Lysine 562 Residue Regulates TLR4 (zeige TLR4 Antikörper)-mediated JNK (zeige MAPK8 Antikörper) and p38 MAPK (zeige MAPK14 Antikörper) Activation

  10. The data emphasize the central role of TAK1 in controlling signaling cascades and functional responses in primary neutrophils, making it a promising target for therapeutic intervention in view of the role of neutrophils in chronic inflammatory conditions.

Mouse (Murine) Mitogen-Activated Protein Kinase Kinase Kinase 7 (MAP3K7) Interaktionspartner

  1. Transforming growth factor-beta activated kinase 1 (TAK1) regulation of sterol-regulatory element-binding proteins (SREBPs) critically contributes to the maintenance of liver homeostasis to prevent steatosis, which is a potentially important mechanism to prevent hepatocellular carcinoma (HCC (zeige FAM126A Antikörper)) development.

  2. TAK1 (zeige NR2C2 Antikörper) regulates Nrf2 (zeige NFE2L2 Antikörper) through modulation of Keap-p62/SQSTM1 (zeige SQSTM1 Antikörper) interaction. This regulation is important for homeostatic antioxidant protection in the intestinal epithelium.

  3. Mekk1 (zeige MAP2K1 Antikörper) (encoded by Map3k1 (zeige MAP3K1 Antikörper)) signaling activates Mapks to regulate Cdkn1b (zeige CDKN1B Antikörper) (encoding p27(Kip1 (zeige CDKN1B Antikörper))) expression and p27(Kip1 (zeige CDKN1B Antikörper))-dependent proliferative expansion in response to antigen.

  4. TRADD (zeige TRADD Antikörper) knockout blunts pressure overload-induced cardiac hypertrophy through mediating TAK1 (zeige NR2C2 Antikörper)/p38 MAPK (zeige MAPK14 Antikörper) but not AKT (zeige AKT1 Antikörper) phosphorylation

  5. this study demonstrates a pivotal role of TAK1 (zeige NR2C2 Antikörper) in dendritic cells in controlling trichloroethylene-induced contact hypersensitivity response and suggests that targeting TAK1 (zeige NR2C2 Antikörper) function in DCs may be a viable approach to preventing and treating TCE-related occupational health hazards

  6. The E3 ligase TRIM8 (zeige TRIM8 Antikörper) is a potent regulator that exacerbates steatohepatitis and metabolic disorders dependent on its binding and ubiquitinating capacity on transforming growth factor-beta-activated kinase 1.

  7. Angiotensin-II up-regulates the Ampkalpha1 (zeige PRKAA1 Antikörper) isoform in renal tissue. Ampkalpha1 (zeige PRKAA1 Antikörper) participates in renal Tak1 (zeige NR2C2 Antikörper) activation and Tak1 (zeige NR2C2 Antikörper)-dependent signaling induced by angiotensin-II.

  8. TRIM8 (zeige TRIM8 Antikörper) could promote K63-linked polyubiquitination of transforming growth factor beta-activated kinase 1 (TAK1), leading to the activation of TAK1 (zeige NR2C2 Antikörper) and enhanced inflammatory responses.

  9. TAK1 (zeige NR2C2 Antikörper) signaling preserved the viability of lambda-chain-positive B cells by maintaining Bcl-2 (zeige BCL2 Antikörper) expression through IKK (zeige CHUK Antikörper)-NF-kappaB (zeige NFKB1 Antikörper) signaling

  10. Data show that TGFbeta (zeige TGFB1 Antikörper)-activated kinase-1 (TAK1 (zeige NR2C2 Antikörper)) activated nuclear factor of activated T-cells (NFAT (zeige NFATC1 Antikörper))/NF-kappa B (NFkappaB (zeige NFKB1 Antikörper)), downregulated BCL2-adenovirus E1B interacting protein 3 (Bnip3 (zeige BNIP3 Antikörper)), and inhibited cardiac cell death.

MAP3K7 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2\; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

Alternative names and synonyms associated with MAP3K7

  • mitogen activated protein kinase kinase kinase 7 (map3k7) Antikörper
  • mitogen activated protein kinase kinase kinase 7 (Map3k7) Antikörper
  • mitogen-activated protein kinase kinase kinase 7 (MAP3K7) Antikörper
  • mitogen-activated protein kinase kinase kinase 7 (Map3k7) Antikörper
  • B430101B05 Antikörper
  • C87327 Antikörper
  • MEKK7 Antikörper
  • si:ch211-225h9.1 Antikörper
  • TAK1 Antikörper
  • TGF1a Antikörper
  • zgc:110612 Antikörper

Bezeichner auf Proteinebene für MAP3K7

mitogen-activated protein kinase kinase kinase 7 , tak1 , TGF-beta-activated kinase TAK1 , TGF-beta activated kinase 1 , TGF-beta-activated kinase 1 , transforming growth factor-beta-activated kinase 1 , mitogen activated protein kinase kinase kinase 7 , transforming growth factor beta-activated kinase 1

GENE ID SPEZIES
553788 Danio rerio
313121 Rattus norvegicus
6885 Homo sapiens
26409 Mus musculus
529146 Bos taurus
100171454 Pongo abelii
Ausgewählte Anbieter für anti-MAP3K7 (MAP3K7) Antikörper
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