ATP-Binding Cassette, Sub-Family D (Ald), Member 1 (ABCD1) ELISA Kits

Bezeichnung:
ATP-Binding Cassette, Sub-Family D (Ald), Member 1 ELISA Kits (ABCD1)
Auf www.antikoerper-online.de finden Sie aktuell 4 ATP-Binding Cassette, Sub-Family D (Ald), Member 1 (ABCD1) ELISA Kits von 4 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen ATP-Binding Cassette, Sub-Family D (Ald), Member 1 Antikörper (33) und und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 39 ATP-Binding Cassette, Sub-Family D (Ald), Member 1 Produkte verfügbar.
Synonyme:
ABC42, ABCD1, Ald, Aldgh, ALDP, AMN, F2G19.18, F2G19_18, RGD1562128, WPP domain protein 2, zgc:172102
list all ELISA KIts Gen GeneID UniProt
Human ABCD1 ABCD1 215 P33897
Maus ABCD1 ABCD1 11666 P48410
ABCD1 363516  

Alle Spezies anzeigen

Weitere Synonyme anzeigen

ATP-Binding Cassette, Sub-Family D (Ald), Member 1 (ABCD1) ELISA Kits nach Reaktivitäten

Select your species

Weitere ELISA Kits für ATP-Binding Cassette, Sub-Family D (Ald), Member 1 Interaktionspartner

Human ATP-Binding Cassette, Sub-Family D (Ald), Member 1 (ABCD1) Interaktionspartner

  1. ABCD1 and ABCD2 (zeige Abcd2 ELISA Kits) are involved in the transport of long and very long chain fatty acids (VLCFA) or their CoA-derivatives into peroxisomes with different substrate specificities, while ABCD3 (zeige ABCD3 ELISA Kits) is involved in the transport of branched chain acyl-CoA (zeige GNPAT ELISA Kits) into peroxisomes.ABCD4 is deduced to take part in the transport of vitamin B12 (zeige NDUFB3 ELISA Kits) from lysosomes into the cytosol.

  2. This study showed that the mutations of were detected in SPG11 (zeige SPG11 ELISA Kits), ATL1 (zeige ATL1 ELISA Kits), NIPA1 (zeige NIPA1 ELISA Kits), and ABCD1 in patient with hereditary spastic paraplegia.

  3. CCALD is the most common phenotype (64%) in our Chinese patients with X-ALD. Eight novel mutations in the ABCD1 gene identified are disease-causing mutations.

  4. The current study demonstrates that a single splicing mutation affects the ABCD1 transcripts and the ALDP protein function.

  5. both BCAP31 (zeige BCAP31 ELISA Kits) and ABCD1 were associated with hepatic cholestasis and death before 1 year. Remarkably, a patient with an isolated deletion at the 3'-end of SLC6A8 (zeige SLC6A8 ELISA Kits) had a similar severe phenotype as seen in BCAP31 (zeige BCAP31 ELISA Kits) deficiency

  6. Exome sequencing in two brothers with distinct phenotype including congenital language disorder, growth retardation, intellectual disability and urinary and fecal incontinence, identifies missense mutations in ABCD1 and DACH2 (zeige DACH2 ELISA Kits).

  7. As a result of loss of ABCD1, there is pathogenic accumulation of very long chain fatty acids which leads to mitochondrial dysfunction.

  8. We detected the same mutation of the ABCD1 gene in two unrelated patients with X-linked adrenoleukodystrophy.

  9. We describe four unrelated women with a late-onset progressive spastic paraparesis and heterozygous mutations in the ABCD1 gene

  10. X-inactivation pattern of the ABCD1 gene is associated with symptomatic status in female X-linked adrenoleukodystrophy carriers.

Mouse (Murine) ATP-Binding Cassette, Sub-Family D (Ald), Member 1 (ABCD1) Interaktionspartner

  1. ABCD1 and its homolog ABCD2 (zeige Abcd2 ELISA Kits) exist mainly as homotetramers in the peroxisomal membrane

  2. during the active myelination phase the microsomal fatty acid elongation activity is stimulated in abcd1-deficient mice

  3. Deletion of AMPKalpha1 (zeige PRKAA1 ELISA Kits) in the mixed glial cells of Abcd1-KO mice induced spontaneous mitochondrial dysfunction

  4. Abcd2 (zeige Abcd2 ELISA Kits) is a strong modifier of the metabolic impairments in peritoneal macrophages of ABCD1-deficient mice

  5. Data indicate that astrocytes from adrenoleukodystrophy protein Abcd1-/- mice respond sensitively to long-term very-long-chain fatty acids (VLCFA) treatment.

  6. Our data support a link between oxidative stress and the deficiency of Abcd1 or Acox1 (zeige ACOX1 ELISA Kits) peroxisomal proteins.

  7. Study demonstrates that oxidative damage to proteins specifically affects five key enzymes of glycolysis and TCA (Tricarboxylic acid) cycle in spinal cords of Abcd1(-) mice.

  8. ALDP facilitates the interaction between peroxisomes and mitochondria, resulting, when ALDP is deficient in X-ALD, in increased VLCFA accumulation

  9. Accumulation of very long-chain fatty acids does not affect mitochindrial function in Abcd1 protein deficiency.

  10. Abcd1 and Abcd2 (zeige Abcd2 ELISA Kits) gene silencing sensitizes astrocytes for inflammation and may have a role in X-adrenoleukodystrophy

ATP-Binding Cassette, Sub-Family D (Ald), Member 1 (ABCD1) Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system.

Alternative names and synonyms associated with ATP-Binding Cassette, Sub-Family D (Ald), Member 1 (ABCD1)

  • ATP-binding cassette, sub-family D (ALD), member 1 (abcd1) Elisa Kit
  • ATP-binding cassette, sub-family D (ALD), member 1 (ABCD1) Elisa Kit
  • ATP-binding cassette sub-family D member 1 (CpipJ_CPIJ013253) Elisa Kit
  • ATP-binding cassette sub-family D member 1 (VDBG_05717) Elisa Kit
  • ATP-binding cassette sub-family D member 1 (ABCD1) Elisa Kit
  • ATP-binding cassette, sub-family D (ALD), member 1 (Abcd1) Elisa Kit
  • ATP-binding cassette, subfamily D (ALD), member 1 (Abcd1) Elisa Kit
  • WPP domain-containing protein 2 (WPP2) Elisa Kit
  • ABC42 Elisa Kit
  • ABCD1 Elisa Kit
  • Ald Elisa Kit
  • Aldgh Elisa Kit
  • ALDP Elisa Kit
  • AMN Elisa Kit
  • F2G19.18 Elisa Kit
  • F2G19_18 Elisa Kit
  • RGD1562128 Elisa Kit
  • WPP domain protein 2 Elisa Kit
  • zgc:172102 Elisa Kit

Bezeichner auf Proteinebene für ABCD1

ATP-binding cassette, sub-family D (ALD), member 1 , adrenoleukodystrophy protein , ATP-binding cassette sub-family D member 1 , ATP-binding cassette sub-family D member 1-like , ATP-binding cassette, sub-family D, member 1 , X-linked adrenoleukodystrophy (ALD) gene homolog

GENE ID SPEZIES
495468 Xenopus laevis
515178 Bos taurus
566367 Danio rerio
612520 Canis lupus familiaris
696794 Macaca mulatta
6046470 Culex quinquefasciatus
9531595 Verticillium alfalfae VaMs.102
100328741 Oryctolagus cuniculus
100493545 Xenopus (Silurana) tropicalis
100519529 Sus scrofa
100027916 Monodelphis domestica
100586126 Nomascus leucogenys
215 Homo sapiens
11666 Mus musculus
363516 Rattus norvegicus
841123 Arabidopsis thaliana
Ausgewählte Anbieter für ATP-Binding Cassette, Sub-Family D (Ald), Member 1 (ABCD1) ELISA Kits
Haben Sie etwas anderes gesucht?