anti-Ratte (Rattus) SPAG5 Antikörper für Immunofluorescence (Paraffin-embedded Sections)

Recommended SPAG5 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Sperm Associated Antigen 5 (SPAG5) Antikörper
  • SPAG5
  • DEEPEST
  • MAP126
  • hMAP126
  • AI874642
  • D11Bhm180e
  • Deepest
  • Mastrin
  • S17
  • sperm associated antigen 5
  • sperm-associated antigen 5
  • SPAG5
  • LOC739263
  • Spag5
Epitop
AA 1120-1170
4
4
2
2
2
2
Reaktivität
Human, Maus, Ratte (Rattus)
33
6
3
1
1
1
1
Wirt
Kaninchen
30
4
Klonalität
Polyklonal
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
29
11
8
7
7
3
2
2
Optionen
Hersteller
Anmelden zum Anzeigen
Hersteller Produkt- Nr.
Anmelden zum Anzeigen
Request

Produkt kostenlos erhalten?

Für Ihre Validierungsdaten erstatten wir Ihnen den vollen Kaufpreis. Ich möchte dieses Produkt validieren

Mehr erfahren

Bilder

Produktnummer ABIN672261
$ 306.90
Zzgl. Versandkosten $45.00

General

Antigen Sperm Associated Antigen 5 (SPAG5) Antikörper
Epitop AA 1120-1170
(4), (4), (2), (2), (2), (2)
Reaktivität Human, Maus, Ratte (Rattus)
(33), (6), (3), (1), (1), (1), (1)
Wirt Kaninchen
(30), (4)
Klonalität
Polyklonal
Applikation Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(29), (11), (8), (7), (7), (3), (2), (2)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-SPAG5 Antikörper

Target Details SPAG5 Anwendungsinformationen Handhabung Bilder
Reinigung Purified by Protein A.
Immunogen KLH conjugated synthetic peptide derived from human SPAG5/MAP126
Isotyp IgG

Target Details SPAG5

Produktdetails anti-SPAG5 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung SPAG5 (SPAG5 Antibody Abstract)
Hintergrund

Essential component of the mitotic spindle required for normal chromosome segregation and progression into anaphase. Required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. In complex with SKAP, promotes stable microtubule-kinetochore attachments. May contribute to the regulation of separase activity. May regulate AURKA localization to mitotic spindle, but not to centrosomes and CCNB1 localization to both mitotic spindle and centrosomes. In non-mitotic cells, upon stress induction, inhibits mammalian target of rapamycin complex 1 (mTORC1) association and recruits the mTORC1 component RPTOR to stress granules (SGs), thereby preventing mTORC1 hyperactivation-induced apoptosis. May enhance GSK3B-mediated phosphorylation of other substrates, such as MAPT/TAU.

Subcellular location: Cytoplasm

Synonyms: MAP126, DEEPEST, hMAP126, Sperm-associated antigen 5, Astrin, Mitotic spindle-associated protein p126, SPAG5

Gen-ID 10615
UniProt Q96R06
Pathways M Phase

Anwendungsinformationen

Produktdetails anti-SPAG5 Antikörper Target Details SPAG5 Handhabung Bilder zurück nach oben
Applikationshinweise WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-SPAG5 Antikörper Target Details SPAG5 Anwendungsinformationen Bilder zurück nach oben
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C
Haltbarkeit 12 months

Bilder

Produktdetails anti-SPAG5 Antikörper Target Details SPAG5 Anwendungsinformationen Handhabung zurück nach oben
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Sperm Associated Antigen 5 (SPAG5) (AA 1120-1170) antibody (ABIN672261) Formalin-fixed and paraffin embedded rat brain labeled with Rabbit Anti SPAG5/MAP126/...
Immunohistochemistry (IHC) image for anti-Sperm Associated Antigen 5 (SPAG5) (AA 1120-1170) antibody (ABIN672261) Formalin-fixed and paraffin embedded rat testis labeled with Rabbit Anti SPAG5/MAP126...