anti-Kaninchen STAT5A Antikörper für Western Blotting

Recommended STAT5A Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Signal Transducer and Activator of Transcription 5A (STAT5A) Antikörper
  • MGF
  • STAT5
  • AA959963
  • Stat5
  • STAT5A/MGF
  • STATA5
  • STAT5A
  • stat5
  • stat5b
  • stat5a
  • signal transducer and activator of transcription 5A
  • signal transducer and activator of transcription 5a
  • signal transducer and activator of transcription 5B L homeolog
  • STAT5A
  • Stat5a
  • stat5a
  • LOC100348518
  • LOC100716811
  • stat5b.L
Epitop
C-Term
101
55
46
22
19
16
9
8
6
6
5
5
5
5
4
4
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus), Schaf
488
225
193
34
23
18
17
16
7
3
3
1
1
1
1
Wirt
Kaninchen
353
141
14
Klonalität
Polyklonal
Konjugat
Dieser STAT5A Antikörper ist unkonjugiert
13
13
11
9
8
8
5
5
4
4
4
4
4
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
Western Blotting (WB)
393
230
163
96
89
86
46
44
26
17
11
9
7
7
6
4
2
2
2
1
1
1
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Bilder

Produktnummer ABIN2780480
$ 289.00
Zzgl. Versandkosten $45.00
Relevance Score ABIN Application Konjugat Host Isotype Epitope Hersteller Clonality References Details
1 ABIN5596749 ELISA WB Rabbit IgG N-Term, meArg31 Anmelden zum Anzeigen Polyclonal
1 ABIN602353 IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal
1 ABIN602354 IHC WB Rabbit IgG Anmelden zum Anzeigen Polyclonal

General

Antigen Signal Transducer and Activator of Transcription 5A (STAT5A) Antikörper
Epitop C-Term
(101), (55), (46), (22), (19), (16), (9), (8), (6), (6), (5), (5), (5), (5), (4), (4), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd, Human, Maus, Schwein, Kaninchen, Ratte (Rattus), Schaf
(488), (225), (193), (34), (23), (18), (17), (16), (7), (3), (3), (1), (1), (1), (1)
Wirt Kaninchen
(353), (141), (14)
Klonalität
Polyklonal
Konjugat Dieser STAT5A Antikörper ist unkonjugiert
(13), (13), (11), (9), (8), (8), (5), (5), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Western Blotting (WB)
(393), (230), (163), (96), (89), (86), (46), (44), (26), (17), (11), (9), (7), (7), (6), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1)
Pubmed 2 Publikationen vorhanden
Hersteller Anmelden zum Anzeigen

Produktdetails anti-STAT5A Antikörper

Target Details STAT5A Anwendungsinformationen Handhabung Referenzen für anti-STAT5A Antikörper (ABIN2780480) Bilder
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN984531.
Sequenz DQAPSPAVCP QAPYNMYPQN PDHVLDQDGE FDLDETMDVA RHVEELLRRP
Homologie Cow: 93%, Dog: 100%, Goat: 93%, Guinea Pig: 79%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 93%, Rabbit: 86%, Rat: 92%, Sheep: 93%
Produktmerkmale This is a rabbit polyclonal antibody against STAT5A. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Immunogen The immunogen is a synthetic peptide directed towards the C terminal region of human STAT5A

Target Details STAT5A

Produktdetails anti-STAT5A Antikörper Anwendungsinformationen Handhabung Referenzen für anti-STAT5A Antikörper (ABIN2780480) Bilder zurück nach oben
Antigen
Andere Bezeichnung STAT5A (STAT5A Antibody Abstract)
Hintergrund STAT5A is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGF, STAT5
Protein Interaction Partner: TCF12, NLK, LEF1, NARF, CBL, UBC, ESR1, HELZ, UGT2B4, STAT5A, POM121C, WASH2P, AQP11, ZNF596, MRPS6, TXNDC11, RBMX, INSR, GLUD1, FN1, EPAS1, CYP2C9, CSNK2B, JAK2, BTK, EPOR, CRKL, SOCS7, NFKB1, ERBB4, EP300, MYB, SQSTM1, GNB2, SMARCA4, PGR, FGFR2, JAK3, C
Protein Size: 794
Molekulargewicht 91 kDa
Gen-ID 6776
NCBI Accession NM_003152, NP_003143
UniProt P42229
Pathways JAK-STAT Signalweg, RTK Signalweg, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation

Anwendungsinformationen

Produktdetails anti-STAT5A Antikörper Target Details STAT5A Handhabung Referenzen für anti-STAT5A Antikörper (ABIN2780480) Bilder zurück nach oben
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 794 AA

Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-STAT5A Antikörper Target Details STAT5A Anwendungsinformationen Referenzen für anti-STAT5A Antikörper (ABIN2780480) Bilder zurück nach oben
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-STAT5A Antikörper (ABIN2780480)

Produktdetails anti-STAT5A Antikörper Target Details STAT5A Anwendungsinformationen Handhabung Bilder zurück nach oben
Produkt verwendet in:

Murayama, Ohmori, Fujimura, Minami, Yasuzawa-Tanaka, Kuroda, Oie, Daitoku, Okuwaki, Nagata, Fukamizu, Kimura, Shimizu, Yanagisawa: "Epigenetic control of rDNA loci in response to intracellular energy status." in: Cell, Vol. 133, Issue 4, pp. 627-39, 2008

Allgemeine Veröffentlichungen

Subtil-Rodríguez, Millán-Ariño, Quiles, Ballaré, Beato, Jordan: "Progesterone induction of the 11beta-hydroxysteroid dehydrogenase type 2 promoter in breast cancer cells involves coordinated recruitment of STAT5A and progesterone receptor to a distal enhancer and polymerase tracking." in: Molecular and cellular biology, Vol. 28, Issue 11, pp. 3830-49, 2008

Bilder

Produktdetails anti-STAT5A Antikörper Target Details STAT5A Anwendungsinformationen Handhabung Referenzen für anti-STAT5A Antikörper (ABIN2780480) zurück nach oben
Bilder des Herstellers
Western Blotting (WB) image for anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (C-Term) antibody (ABIN2780480) anti-Signal Transducer and Activator of Transcription 5A (STAT5A) (C-Term) antibody