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Human Fibronectin ELISA Kit für Sandwich ELISA - ABIN411271
Tang, Song, Shi, Yuan, Li: Dicer knockdown induces fibronectin-1 expression in HEK293T cells via induction of Egr1. in Biochimica et biophysica acta 2010
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Rat (Rattus) Fibronectin ELISA Kit für Sandwich ELISA - ABIN411272
Owerbach, Doyle, Shows: Genetics of the large, external, transformation-sensitive (LETS) protein: assignment of a gene coding for expression of LETS to human chromosome 8. in Proceedings of the National Academy of Sciences of the United States of America 1979
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Mouse (Murine) Fibronectin ELISA Kit für Sandwich ELISA - ABIN921056
Gao, Huang, Li: NOX1 abet mesangial fibrogenesis via iNOS induction in diabetes. in Molecular and cellular biochemistry 2013
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Rat (Rattus) Fibronectin ELISA Kit für Sandwich ELISA - ABIN2684301
Kornblihtt, Umezawa, Vibe-Pedersen, Baralle: Primary structure of human fibronectin: differential splicing may generate at least 10 polypeptides from a single gene. in The EMBO journal 1985
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Injection of alpha5beta1 protein rescued the Fibronectin layer and then the myocardial precursor migration in snai1b knockdown embryos.
Fibronectin, a main component of the extracellular matrix, is induced and deposited after cardiac damage
Fibronectin deficiency resulted in a dramatic reduction of mesoderm accompanied by endodermal expansion in zebrafish embryos.
Data indicate that focal adhesion kinase (FAK) activity may be a mediator of the integrin alpha5/Fn1 interaction during zebrafish lens fiber morphogenesis.
reduction of fn1 function enables rescue of cardiac fusion in hand2 (zeige HAND2 ELISA Kits) mutants
Fibronectin regulates epithelial organization during myocardial migration in zebrafish.
Fibronectin is readily modified by ONOOH at low (physiologically-relevant) molar ratios of oxidant to protein.
The 45 kDa gelatin-binding domain of fibronectin is responsible for the binding to TGM2 (zeige TGM2 ELISA Kits).
Proteomics study showed a strong association of FN1, A2M (zeige A2M ELISA Kits), C4BPA (zeige C4BPA ELISA Kits) and CFB (zeige CFB ELISA Kits) in molecular subtypes of breast cancer. The findings also revealed the altered level expressions of these selected proteins could classify BC subtypes through plasma and tissue based expression analysis
FN1/CCL2 (zeige CCL2 ELISA Kits) levels are elevated in the bronchoalveolar lavage fluid from pulmonary sarcoidosis patients.
Cancer-associated fibroblasts organize the fibronectin matrix and promote directional prostate cancer cell migration.
FN1 mutations that cause defective fibronectin secretion are found in SMD.
FN1 overexpression is an important determinant of thyroid cancer aggressiveness.
Thyroid hormone (zeige PTH ELISA Kits) T3 induces fibronectin and HIF-1alpha (zeige HIF1A ELISA Kits) synthesis via PI3K (zeige PIK3CA ELISA Kits)/AKT (zeige AKT1 ELISA Kits) signaling pathway.
Fibronectin and Hepatocyte Growth Factor (zeige HGF ELISA Kits) were shown to be produced by lung fibroblasts and, furthermore, to enhance malignant pleural mesothelioma cell migration and invasion
Study identifies four likely Tourette disorder risk genes with multiple de novo damaging variants in unrelated probands: WWC1 (WW and C2 domain containing 1 (zeige WWC1 ELISA Kits)), CELSR3 (Cadherin EGF LAG seven-pass G-type receptor 3 (zeige CELSR3 ELISA Kits)), NIPBL (zeige NIPBL ELISA Kits) (Nipped (zeige RPL38 ELISA Kits)-B-like), and FN1 (fibronectin 1).
PD increased CKIP-1 and Nrf2 (zeige NFE2L2 ELISA Kits) levels in the kidney tissues as well as improved the anti-oxidative effect and renal dysfunction of diabetic mice, which eventually reversed the up-regulation of FN and ICAM-1 (zeige ICAM1 ELISA Kits)
Histone methyltransferase Suv39h1 (zeige SUV39H1 ELISA Kits) attenuates high glucose-induced fibronectin and p21(WAF1 (zeige CDKN1A ELISA Kits)) in mesangial cells
fibronectin has a critical role in tissue morphogenesis and the development of tissue heterogeneities
The aged stem cell niche in skeletal muscle contains reduced levels of FN, leading to detrimental consequences for the function and maintenance of muscle stem cells (MuSCs). FN is a preferred adhesion substrate for MuSCs and integrin-mediated signaling via focal adhesion kinase and the p38 MAPK (zeige MAPK14 ELISA Kits) pathway is strongly de-regulated in MuSCs from aged mice because of insufficient attachment to the niche.
analysis of novel functions for two fibronectin isoforms and the mediating receptors in osteoblast differentiation
scleraxis was required for TGFbeta-induced fibronectin expression: TGFbeta lost its ability to induce fibronectin expression following scleraxis knockdown.
The results very comprehensively demonstrate distinct signaling pathways that regulate microfilament organization, lamellipodial structures, spreading, and movement of cells plated on galectin-3 (zeige LGALS3 ELISA Kits) as opposed to fibronectin.
Thus, similarly to growth factor signaling, fibronectin matrix assembly during early development can be both autocrine and paracrine.
These results suggest that the Rac1 regulation of the FN arrangement is involved in retinoic acid-induced cleft palate.
Fibrillar cellular fibronectin supports platelet adhesion, activation, aggregation and procoagulant activity via the interplay of a series of receptors i.e. integrins alpha5beta1 and alphaIIbbeta3, the GPIb-V-IX complex, GPVI (zeige GP6 ELISA Kits) and Toll-like receptor 4 (zeige TLR4 ELISA Kits).
plasma FN assembly into bone matrix in vitro requires FXIIIA transglutaminase activity making pFN assembly an active, osteoblast-mediated process.
Fetal and adult human skin fibroblasts retain their differential proliferative response to TGF-beta (zeige TGFB1 ELISA Kits) when cultured in the presence of fibronectin and unpolymerized or polymerized collagen.
Putative function of fibronectin and its receptor (integrin alpha(5 (zeige ITGA5 ELISA Kits))beta(1)) in male and female gametes during bovine fertilization in vitro.
These results highlight a crucial role for caveolin-1 (zeige CAV1 ELISA Kits) in negative regulation of membrane microdomain mobility, thereby affecting endocytosis of bacteria-engaged integrins.
P. multocida-Fn interaction may play a role in the bacterium adherence to host cells, and this may be mediated by bacterial surface proteins with preferential affinity for the Hep-1 binding domain of Fn
The expression of extracellular matrix molecules fibronectin and osteopontin (zeige SPP1 ELISA Kits) in vitreous and retina samples in autoimmune uveitis was investigated.
The obtained results suggest that propolis modifies fibronectin metabolism in the course of wound healing process.
The relationship between hyaluronan synthesis and levels of versican (zeige Vcan ELISA Kits), fibronectin and several other extracellular matrix components in trabecular meshwork cells from the anterior segment of the eye was investigated.
fibronectin has a cryptic binding site for tenascin (zeige TNC ELISA Kits)
Transplantation experiments demonstrate a tissue-autonomous role for DS epimerase (zeige DSE ELISA Kits)-1 in cranial neural crest (NC) cell migration in vivo Cranial NC explant and single-cell cultures indicate a requirement of DS epimerase (zeige DSE ELISA Kits)-1 in cell adhesion, spreading and extension of polarized cell processes on fibronectin.
This gene encodes fibronectin, a glycoprotein present in a soluble dimeric form in plasma, and in a dimeric or multimeric form at the cell surface and in extracellular matrix. Fibronectin is involved in cell adhesion and migration processes including embryogenesis, wound healing, blood coagulation, host defense, and metastasis. The gene has three regions subject to alternative splicing, with the potential to produce 20 different transcript variants. However, the full-length nature of some variants has not been determined.
, gene C
, cold-insoluble globulin
, migration-stimulating factor
, cumulus cell-specific fibronectin 1 transcript
, embryo-specific fibronectin 1 transcript
, fibronectin ED-A- region
, fibronectin variable region