anti-Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2) Antikörper

Bezeichnung:
anti-Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) Antikörper (PTGS2)
Auf www.antikoerper-online.de finden Sie aktuell 233 Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2) Antikörper von 27 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) Kits (69) und Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) Proteine (10) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 323 Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) Produkte verfügbar.
Synonyme:
CEF147, COII, Cox-2, Cox2, GRIPGHS, hCox-2, PGG/HS, PGHS-2, PGHS2, PHS-2, PHSII, PTGS2, TIS10

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Am meisten referenzierte anti-Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) Antikörper

  1. Human Monoclonal PTGS2 Primary Antibody für IHC (p) - ABIN1687606 : Yang, Hsu, Meng, Su: Supplement of 5-hydroxytryptophan before induction suppresses inflammation and collagen-induced arthritis. in Arthritis research & therapy 2015 (PubMed)
    Zeige alle 29 Referenzen für 1687606

  2. Human Monoclonal PTGS2 Primary Antibody für IHC (p) - ABIN1687611 : Carvalho, Pires, Prada, Ferreira, Queiroga: Positive Interplay Between CD3+ T-lymphocytes and Concurrent COX-2/EGFR Expression in Canine Malignant Mammary Tumors. in Anticancer research 2015 (PubMed)
    Zeige alle 24 Referenzen für 1687611

  3. Human Polyclonal PTGS2 Primary Antibody für IF (p), IHC (p) - ABIN672471 : Gao, Wen, Yang, Lu, Tong, Huang, Liu, Tang: Celecoxib ameliorates portal hypertension of the cirrhotic rats through the dual inhibitory effects on the intrahepatic fibrosis and angiogenesis. in PLoS ONE 2013 (PubMed)
    Zeige alle 9 Referenzen für 672471

  4. Chicken Monoclonal PTGS2 Primary Antibody für WB - ABIN967824 : Hla, Neilson: Human cyclooxygenase-2 cDNA. in Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)
    Zeige alle 5 Referenzen für 967824

  5. Human Polyclonal PTGS2 Primary Antibody für EIA, IF - ABIN951767 : Duggan, Walters, Musee, Harp, Kiefer, Oates, Marnett: Molecular basis for cyclooxygenase inhibition by the non-steroidal anti-inflammatory drug naproxen. in The Journal of biological chemistry 2010 (PubMed)
    Zeige alle 4 Referenzen für 951767

  6. Mouse (Murine) Polyclonal PTGS2 Primary Antibody für IHC (p) - ABIN115419 : Cras, Martin, Gheuens: Gamma-enolase and glial fibrillary acidic protein in nervous system tumors. An immunohistochemical study using specific monoclonal antibodies. in Acta neuropathologica 1988 (PubMed)
    Zeige alle 2 Referenzen für 115419

  7. Human Polyclonal PTGS2 Primary Antibody für IF (p), IHC (p) - ABIN2173482 : Niu, Wang, Li, Mu, Li, Yao, Zhang: Protective effects of Isofraxidin against lipopolysaccharide-induced acute lung injury in mice. in International immunopharmacology 2015 (PubMed)
    Zeige alle 2 Referenzen für 2173482

  8. Human Polyclonal PTGS2 Primary Antibody für WB - ABIN223087 : Majed, Rashid, Khan, Nafees, Ali, Ali, Khan, Hasan, Mehdi, Sultana: Tannic acid mitigates the DMBA/croton oil-induced skin cancer progression in mice. in Molecular and cellular biochemistry 2014 (PubMed)

  9. Human Polyclonal PTGS2 Primary Antibody für ELISA, WB - ABIN184672 : Ballif, Mincek, Barratt, Wilson, Simmons: Interaction of cyclooxygenases with an apoptosis- and autoimmunity-associated protein. in Proceedings of the National Academy of Sciences of the United States of America 1996 (PubMed)

Weitere Antikörper gegen Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) Interaktionspartner

Horse (Equine) Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2) Interaktionspartner

  1. This study showed that COX-1 (zeige PTGS1 Antikörper) and COX-2 in genital carcinomas in the horse is poor; microsomal PGES (zeige PTGES Antikörper)-1 is more prominently expressed.

  2. Progestin treatment does not affect expression of cytokines, steroid receptors, oxytocin receptor (zeige OXTR Antikörper), and cyclooxygenase 2 in fetal membranes and endometrium.

  3. COX-1 (zeige PTGS1 Antikörper) and COX-2 genes were constitutively expressed in baseline samples. Low-flow ischemia resulted in significant upregulation of COX-2 gene expression at each subsequent time point, compared with baseline values.

  4. The role for p38 (zeige MAPK14 Antikörper) mitogen-activated kinase (MAPK (zeige MAPK1 Antikörper)) in the signaling mechanism regulating pro-inflammatory cyclooxygenase (COX (zeige CPOX Antikörper)) gene expression in lipopolysaccharide (LPS (zeige IRF6 Antikörper))-activated equine leukocytes in horses is reported.

  5. In this study, both COX-1 (zeige PTGS1 Antikörper) and COX-2 were expressed in the colon before induced ischemia; ischemic injury increased expression of COX-2.

  6. Immunoreactivity for COX-1 (zeige PTGS1 Antikörper) and COX-2 is high in equine corneal SCC (zeige CYP11A1 Antikörper), possibly indicating that COX (zeige CPOX Antikörper) plays a role in oncogenesis or progression of this tumor type at this site.

  7. It was found that most equine squamous-cell carcinomas and many melanomas appear to express COX-2 and thus could respond to COX-2 inhibitor therapy.

  8. data support the hypothesis that prostaglandin G/H synthase 2(PGHS2)is a target for the antiluteolytic signal produced by equine conceptuses during early pregnancy

Cow (Bovine) Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2) Interaktionspartner

  1. The objective of this study was to evaluate the mRNA expression of prostaglandin-endoperoxide synthase 2 (PTGS 2), prostaglandin F2alpha synthase (PTGFS) and prostaglandin E2 microsomal synthase 1 (mPTGES 1) in the endometrium of repeat-breeding cows with and without subclinical endometritis.

  2. results indicate that nuclear receptor subfamily 1 group D member 1(REV-ERBalpha (zeige NR1D1 Antikörper)) plays an inhibitory role in the expression of prostaglandin-endoperoxide synthase 2(PTGS2) in both bovine USCs and UECs treated with ovarian steroids

  3. This study showed that neutrophils from periparturient heifers show impairment of COX-2 mRNA expression and lactoferrin (zeige LTF Antikörper), suggesting that these mechanisms may contribute to immunosuppression in cows around calving.

  4. Exposure to follicular fluid transiently increased the transcript levels of IL8 (zeige IL8 Antikörper) and PTGS2, and decreased the expression of SOD2 (zeige SOD2 Antikörper), GPX3 (zeige GPX3 Antikörper), DAB2 (zeige DAB2 Antikörper), and NR3C1 (zeige NR3C1 Antikörper). TNF (zeige TNF Antikörper) and IL6 (zeige IL6 Antikörper) levels were also decreased while those of NAMPT (zeige NAMPT Antikörper) were unaffected.

  5. Purinergic P2Y1 receptor (zeige P2RY1 Antikörper) signaling mediates wound stimuli-induced cyclooxygenase-2 expression in intestinal subepithelial myofibroblasts

  6. Data suggest that Escherichia coli infections (here, administration of LPS (zeige IRF6 Antikörper)) provokes luteolysis in diestrus, non-lactating cows but no change in expression of PTGS2 in corpus luteum and has no effect on luteinization in the following cycle.

  7. This study is the first to report the involvement of PGE2 in oocyte MAPK (zeige MAPK1 Antikörper) activation during the maturation process.

  8. Inhibitors of c-Src (zeige SRC Antikörper) (PP2, 10 microm) and PI3K (LY294002, 25 microm) produced a significant decrease in oxytocin-induced PGF (zeige PGF Antikörper)(2 alpha) production and reduced COX2 expression by endometrial epithelial cells.

  9. COX-2 pathway is responsible for the endometrial production of PGE (zeige LIPF Antikörper)(2) in the bovine endometrium during the estrous cycle

  10. the conceptus, through its secretion of IFN-tau, stimulates maternal epithelial expression of COX-2 and GM-CSF (zeige CSF2 Antikörper) during the peri (zeige PLIN1 Antikörper)-attachment period in the cow.

Mouse (Murine) Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2) Interaktionspartner

  1. AhR (zeige AHR Antikörper) controls COX-2 (zeige COX2 Antikörper) protein via mRNA stability.

  2. Podocyte-specific knockout of COX2 (zeige COX2 Antikörper) enhanced albuminuria and did not attenuate the histologic features of diabetic kidney disease.

  3. Salt supplementation during the COX-2 (zeige COX2 Antikörper)-dependent time frame of nephrogenesis partly reverses renal morphological defects in COX-2 (zeige COX2 Antikörper)(-/-) mice and improves kidney function.

  4. Data suggest that induction of Ptgs2 expression in preimplantation uterus may be earliest positive embryo/blastocyst signal for implantation and pregnancy recognition in mice.

  5. the bone regeneration capacity of Cox (zeige CPOX Antikörper)-2KO MDSCs was impaired because of a reduction in cell proliferation and survival capacities, reduction in osteogenic differentiation and a decrease in the ability of the cells to recruit host cells to the injury site.

  6. these studies have demonstrated an important but unexpected role for macrophage COX-2 (zeige COX2 Antikörper)/prostaglandin E2/PGE2 receptor subtype 4 signaling to lessen progression of diabetic kidney disease, unlike the pathogenic effects of increased COX-2 (zeige COX2 Antikörper) expression in intrinsic renal cells.

  7. Data (including data from studies using knockout/mutant mice) suggest that Mir200c (microRNA 200c) is involved in endothelial function/dysfunction via regulation of Cox2 (cyclooxygenase-2) expression; overexpression of Mir200c impairs endothelium-dependent vascular relaxation (EDVR) in non-diabetic mouse aorta, whereas suppression of Mir200c by anti-Mir200c enhances EDVR in diabetic mouse aorta.

  8. data indicate that excessive adipocyte lipolysis activates the JNK (zeige MAPK8 Antikörper)/NFkappaB pathway leading to the up-regulation of COX-2 (zeige COX2 Antikörper) expression and recruitment of inflammatory macrophages.

  9. this study shows that c-Jun (zeige JUN Antikörper) regulates the activation state of macrophages and promotes arthritis via differentially regulating cyclooxygenase-2 and arginase-1 (zeige ARG1 Antikörper) levels

  10. Dimethyl ester of bilirubin exhibits anti-inflammatory activity through inhibition of secretory phospholipase A2 (zeige YWHAZ Antikörper), lipoxygenase and cyclooxygenase.

Human Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2) Interaktionspartner

  1. PTGS2 rs20417CC genotype is associated with carotid plaque vulnerability, platelet activation and TXA2 (zeige TBXA2R Antikörper) levels in ischemic stroke patients.

  2. Current results suggest that COX-2 (zeige COX2 Antikörper) rs689466, rs5275, and rs20417 polymorphisms are not associated with head and neck squamous cell carcinoma.[meta-analysis]

  3. Specific inhibitors of COX-2 (zeige COX2 Antikörper) and 5-LOX (zeige ALOX5 Antikörper) decreased formation of HKD2 and HKE2 (zeige PFDN6 Antikörper) Platelets did not form HKs from exogenous 5S-hydroxyeicosatetraenoic acid, implying that COX-1 (zeige COX1 Antikörper) is not involved

  4. Leptin (zeige LEP Antikörper) induced COX-2 (zeige COX2 Antikörper) expression, promoter activity, and increased the production of prostaglandin E2.

  5. AhR (zeige AHR Antikörper) controls COX-2 (zeige COX2 Antikörper) protein via mRNA stability.

  6. data expand upon the roles of COX-2 (zeige COX2 Antikörper) in shaping the structure and function of the extracellular matrix in primary and metastatic tumors

  7. a stiffness-dependent YAP (zeige YAP1 Antikörper)/TAZ (zeige TAZ Antikörper)-mediated positive feedback loop that drives remodeling phenotypes in pulmonary artery smooth muscle cells via reduced COX-2 (zeige COX2 Antikörper) and prostaglandin activity.

  8. Human apoA-I (zeige APOA1 Antikörper) was overexpressed by transfection in BEL (zeige LHX2 Antikörper)-7402 hepatocytes and by an adenoviral vector in C57BL/6J mice fed a methionine choline-deficient diet. The overexpression of apoA-I (zeige APOA1 Antikörper) in both models resulted in decreased reactive oxygen species and lipid peroxidation levels, as well as a reduced MAPK (zeige MAPK1 Antikörper) phosphorylation and decreased expression levels of c-Fos and COX-2 (zeige COX2 Antikörper).

  9. higher COX-2 (zeige COX2 PLURAL_@3975@) expression levels in biopsy specimens may be used to decide re-biopsy in borderline preoperative PSA (zeige PLAG1 PLURAL_@3975@) levels as well as in the cases with suspicious pathological findings for cancer

  10. short hairpin-mediated silencing of SEMA7A (zeige SEMA7A Antikörper) reveals roles for semaphorin 7a (zeige SEMA7A Antikörper) in the promotion of DCIS growth, motility and invasion as well as lymphangiogenesis in the tumor microenvironment. Our studies also uncover a relationship between COX-2 (zeige COX2 Antikörper) and semaphorin 7a (zeige SEMA7A Antikörper) expression and suggest that semaphorin 7a (zeige SEMA7A Antikörper) promotes tumor cell invasion on collagen and lymphangiogenesis via activation of b1-integrin receptor

Pig (Porcine) Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2) Interaktionspartner

  1. These findings suggest that nuclear factor kappa B(NF-kappaB (zeige NFKB1 Antikörper)) and cyclooxygenase-2 play roles in epidermal cell regeneration following beta-irradiation of mini-pig skin.

  2. COX2 expression is upregulated in CAVD, and its activity contributes to osteogenic gene induction and valve calcification in vitro and in vivo.

  3. These results suggest that COX-2 plays a role in the pathogenesis of Mycoplasma hyopneumoniae -infection.

  4. Brain death increases the expression of COX-1 (zeige COX1 Antikörper) and COX-2 mRNA in the renal medulla

  5. COX-2 is differentially expressed in normal versus lungworm-infected lungs of pigs and is likely to be involved in the pathogenesis of porcine parasitic bronchopneumonia.

  6. In porcine vas (zeige AVP Antikörper) deferens epithelial cell monolayers, increases in anion secretion were associated with preferential upregulation of PTGS2 at the mRNA and protein levels.

  7. expression appears to be positively and negatively regulated by p38 MAPK (zeige MAPK14 Antikörper) and JNK (zeige MAPK8 Antikörper) pathways; alternatively, ERK1/2 (zeige MAPK1/3 Antikörper) appear to be involved in COX-2-independent reparative events that remain to be defined

  8. Neutrophils augment recovery of transepithelial electrical resistance in ischemia-injured ileal mucosa via IL-1beta (zeige IL1B Antikörper)-dependent upregulation of COX-2. (Cyclooxygenase 2)

  9. Administration of estrogen early in pregnancy alters endometrial prostaglandin-endoperoxide synthase 2 (PTGS2) mRNA and protein expression, which may disrupt pregnancy causing total embryonic loss during implantation in the pig.

  10. The effect of EGF (zeige EGF Antikörper) on pro-inflammatory cytokines, tumor necrosis factor-alpha (TNF-alpha (zeige TNF Antikörper)) and cyclooxygenase-2 (COX-2), levels during wound healing in swine is reported.

Rabbit Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2) Interaktionspartner

  1. results revealed that a transient episode of raised-intensity phonation causes a significant increase in vocal fold inflammatory mRNA expression - IL-1beta (zeige IL1B Antikörper),COX-2 (zeige COX2 Antikörper), and TGFbeta1 (zeige TGFB1 Antikörper)

  2. The result demonstrate that mechanical stress on synovial cells induces gene expressions of COX-2 (zeige COX2 Antikörper).

  3. Diabetes enhances the vasodilator response of the rabbit carotid artery to testosterone by a mechanism that includes an increased modulatory activity of the endothelial nitric oxide and an augmented release of COX-2 (zeige COX2 Antikörper) vasodilator, prostacyclin.

  4. Local induction of COX-2 (zeige COX2 Antikörper) during atherosclerosis decreased the sensitivity to norepinephrine and that COX-2 (zeige COX2 Antikörper) inhibitors may increase vascular reactivity at sites of atherosclerotic lesions.

Goat Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2) Interaktionspartner

  1. The vesicular gland of castrated goats showed significantly lower AR and COX-2 (zeige COX2 Antikörper) immuno-expression than intact goats indicating that both AR and COX-2 (zeige COX2 Antikörper) are androgen dependent.

Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2) Antigen-Profil

Beschreibung des Gens

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis.

Alternative names and synonyms associated with Prostaglandin-Endoperoxide Synthase 2 (Prostaglandin G/H Synthase and Cyclooxygenase) (PTGS2)

  • cyclooxygenase-2 (COX-2) Antikörper
  • prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (PTGS2) Antikörper
  • cyclooxygenase-2 (cox-2) Antikörper
  • cyclooxygenase 2 (cox-2) Antikörper
  • prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (ptgs2) Antikörper
  • cytochrome c oxidase subunit II (COX2) Antikörper
  • olfactory receptor, family 2, subfamily W, member 1-like (LOC782475) Antikörper
  • prostaglandin-endoperoxide synthase 2 (Ptgs2) Antikörper
  • CEF147 Antikörper
  • COII Antikörper
  • Cox-2 Antikörper
  • Cox2 Antikörper
  • GRIPGHS Antikörper
  • hCox-2 Antikörper
  • PGG/HS Antikörper
  • PGHS-2 Antikörper
  • PGHS2 Antikörper
  • PHS-2 Antikörper
  • PHSII Antikörper
  • PTGS2 Antikörper
  • TIS10 Antikörper

Bezeichner auf Proteinebene für PTGS2

cyclooxygenase-2 , cyclooxygenase 2 , prostaglandin G/H synthase 2 , prostaglandin G/H synthase and cyclooxygenase , prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) , prostaglandin G/H synthase 2-like , PES-2 , PGH synthase 2 , PHS II , glucocorticoid-regulated inflammatory cyclooxygenase , gripghs , macrophage activation-associated marker protein P71/73 , prostaglandin H2 synthase 2 , PGHS-2 , cyclooxygenase 2b , COX-2 , prostaglandin G/H synthase-2 , cyclooxygenase, prostaglandin endoperoxide H synthase-2 , prostaglandin H synthase-2 , cyclooxygenase type 2 , mitogen-inducible PGHS

GENE ID SPEZIES
100033836 Equus caballus
100126581 Felis catus
100136025 Oncorhynchus mykiss
100136456 Salmo salar
446781 Xenopus laevis
469616 Pan troglodytes
595089 Xenopus (Silurana) tropicalis
716671 Macaca mulatta
100407639 Callithrix jacchus
100436566 Pongo abelii
807845 Equus caballus
808252 Ovis aries
782475 Bos taurus
19225 Mus musculus
29527 Rattus norvegicus
100135607 Cavia porcellus
5743 Homo sapiens
282023 Bos taurus
791253 Equus caballus
443460 Ovis aries
442942 Canis lupus familiaris
397590 Sus scrofa
100009248 Oryctolagus cuniculus
396451 Gallus gallus
100860905 Capra hircus
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