anti-Maus Caspase 8 Antikörper für Enzyme Immunoassay

Recommended Caspase 8 Antibody (geliefert von: Anmelden zum Anzeigen )

Antigen
Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) Antikörper
  • casp8-A
  • xCaspase-8
  • casp8
  • CASP8
  • CASP-8
  • FLICE
  • MACH
  • Mch5
  • ALPS2B
  • CAP4
  • Casp-8
  • MCH5
  • caspase-8
  • zgc:92075
  • caspase 8, apoptosis-related cysteine peptidase
  • death related ced-3/Nedd2-like protein
  • caspase-8
  • caspase 8
  • casp8
  • Dredd
  • CASP8
  • AaeL_AAEL014148
  • LOC100222284
  • Casp8
  • LOC100348477
Epitop
C-Term
42
19
18
16
15
12
10
10
9
8
7
6
6
6
6
5
5
5
4
4
4
3
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
359
119
94
25
21
20
3
2
1
Wirt
Kaninchen
277
115
10
2
Klonalität
Polyklonal
Konjugat
Dieser Caspase 8 Antikörper ist unkonjugiert
18
13
8
4
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Applikation
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
360
109
92
79
51
36
36
27
14
13
9
7
6
5
2
2
2
1
1
1
1
Hersteller
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Hersteller Produkt- Nr.
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Produktnummer ABIN5554665
357,50 €
Zzgl. Versandkosten 20,00 € und MWSt
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1 ABIN187452 EIA IHC (fro) WB Rat IgG1 Anmelden zum Anzeigen 1G12
1 ABIN1105678 EIA FACS IHC (p) WB Mouse IgG1 Anmelden zum Anzeigen 1H11

General

Antigen Caspase 8, Apoptosis-Related Cysteine Peptidase (CASP8) Antikörper
Epitop C-Term
(42), (19), (18), (16), (15), (12), (10), (10), (9), (8), (7), (6), (6), (6), (6), (5), (5), (5), (4), (4), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reaktivität Human, Maus, Ratte (Rattus)
(359), (119), (94), (25), (21), (20), (3), (2), (1)
Wirt Kaninchen
(277), (115), (10), (2)
Klonalität
Polyklonal
Konjugat Dieser Caspase 8 Antikörper ist unkonjugiert
(18), (13), (8), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applikation Enzyme Immunoassay (EIA), Immunofluorescence (IF), Western Blotting (WB)
(360), (109), (92), (79), (51), (36), (36), (27), (14), (13), (9), (7), (6), (5), (2), (2), (2), (1), (1), (1), (1)
Hersteller Anmelden zum Anzeigen

Produktdetails anti-Caspase 8 Antikörper

Target Details Caspase 8 Anwendungsinformationen Handhabung Bilder
Spezifität Caspase-8 antibody was raised against a 16 amino acid peptide from near the carboxy-terminus of human Caspase-8 isoform A.
Reinigung Affinity chromatography purified via peptide column
Immunogen Virus Casp-8 / FLICE / MACH / Mch5 (C-Terminus) Peptide
Isotyp IgG

Target Details Caspase 8

Produktdetails anti-Caspase 8 Antikörper Anwendungsinformationen Handhabung Bilder zurück nach oben
Antigen
Andere Bezeichnung Caspase-8 (CASP8 Antibody Abstract)
Hintergrund Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens (reviewed in 1 and 2). The apoptotic subfamily can be further divided into initiator caspases, which are activated in response to death signals, and executioner caspases, which are activated by the initiator caspases and are responsible for cleavage of cellular substrates that ultimately lead to cell death (reviewed in 3). Caspase-8 is an initiator caspase that was identified as a member of the Fas/APO-1 death-inducing signaling complex (4). The adaptor molecule FADD couples procaspase-8 to the Fas receptor death domain, subsequent oligomerization promotes procaspase-8 autoactivation (reviewed in 5). FLIP, a catalytically inactive caspase-8-like molecule inhibits these interactions and thus can inhibit apoptosis (6).Synonyms: Apoptotic cysteine protease, Apoptotic protease Mch-5, CAP4, CASP-8, CASP8, FADD-homologous ICE/CED-3-like protease, FADD-like ICE, ICE-like apoptotic protease 5, MCH5, MORT1-associated CED-3 homolog
Gen-ID 841
NCBI Accession NP_001219
UniProt Q14790
Forschungsgebiet Apoptosis/Necrosis
Pathways Apoptose, Caspase Kaskade in der Apoptose, TLR Signalweg, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades

Anwendungsinformationen

Produktdetails anti-Caspase 8 Antikörper Target Details Caspase 8 Handhabung Bilder zurück nach oben
Applikationshinweise ELISA. Western Blot: Caspase-8 antibody can be used for the detection of caspase-8 at 0.5 μg/mL. Depending on cell lines or tissues used, either full-length or other cleavage products maybe observed. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar

Handhabung

Produktdetails anti-Caspase 8 Antikörper Target Details Caspase 8 Anwendungsinformationen Bilder zurück nach oben
Buffer PBS containing 0.02 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store the antibody undiluted at 2-8 °C.