anti-ABL1 (ABL1) Antikörper

Bezeichnung:
anti-C-Abl Oncogene 1, Non-Receptor tyrosine Kinase Antikörper (ABL1)
Auf www.antikoerper-online.de finden Sie aktuell 627 C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) Antikörper von 28 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen ABL1 Proteine (26) und ABL1 Kits (12) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 723 ABL1 Produkte verfügbar.
Synonyme:
Abl, ABL1, ABLL, AI325092, bcr/abl, c-Abl, CABL, cb272, E430008G22Rik, JTK7, MTP, p150, v-abl
Alle Antikörper anzeigen Gen GeneID UniProt
ABL1 25 P00519
ABL1 11350 P00520
ABL1 311860  

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Meistgesuchte Reaktivitäten zu anti-ABL1 (ABL1) Antikörper

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anti-Human ABL1 Antikörper:

anti-Mouse (Murine) ABL1 Antikörper:

anti-Rat (Rattus) ABL1 Antikörper:

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Am meisten referenzierte anti-ABL1 Antikörper

  1. Human Polyclonal ABL1 Primary Antibody für DB, IHC (p) - ABIN389501 : Barnes, McIntosh, Whetton, Daley, Bentley, Baldwin: Chronic myeloid leukaemia: an investigation into the role of Bcr-Abl-induced abnormalities in glucose transport regulation. in Oncogene 2005 (PubMed)
    Zeige alle 6 Referenzen für 389501

  2. Human Polyclonal ABL1 Primary Antibody für DB, IF - ABIN389865 : Kim, Cho, Yoon, Park, Kim, Lee, Chun, Kim, Lee et al.: Interpretation of submicroscopic deletions of the BCR or ABL gene should not depend on extra signal-FISH: problems in interpretation of submicroscopic deletion of the BCR or ABL gene with extra ... in Genes, chromosomes & cancer 2005 (PubMed)
    Zeige alle 5 Referenzen für 389865

  3. Human Polyclonal ABL1 Primary Antibody für IF, IHC (p) - ABIN389502 : Aichberger, Mayerhofer, Krauth, Skvara, Florian, Sonneck, Akgul, Derdak, Pickl, Wacheck, Selzer, Monia, Moriggl, Valent, Sillaber: Identification of mcl-1 as a BCR/ABL-dependent target in chronic myeloid leukemia (CML): evidence for cooperative antileukemic effects of imatinib and mcl-1 antisense oligonucleotides. in Blood 2005 (PubMed)
    Zeige alle 5 Referenzen für 389502

  4. Human Polyclonal ABL1 Primary Antibody für WB - ABIN389507 : Cao, Leng, Liu, Yi, Li, Kufe: Catalase is regulated by ubiquitination and proteosomal degradation. Role of the c-Abl and Arg tyrosine kinases. in Biochemistry 2003 (PubMed)
    Zeige alle 4 Referenzen für 389507

  5. Human Polyclonal ABL1 Primary Antibody für IF, ELISA - ABIN1531424 : Fainstein, Einat, Gokkel, Marcelle, Croce, Gale, Canaani: Nucleotide sequence analysis of human abl and bcr-abl cDNAs. in Oncogene 1990 (PubMed)
    Zeige alle 3 Referenzen für 1531424

  6. Human Polyclonal ABL1 Primary Antibody für ELISA, WB - ABIN1532033 : Shtivelman, Lifshitz, Gale, Roe, Canaani: Alternative splicing of RNAs transcribed from the human abl gene and from the bcr-abl fused gene. in Cell 1986 (PubMed)
    Zeige alle 3 Referenzen für 1532033

  7. Mouse (Murine) Polyclonal ABL1 Primary Antibody für IHC (p), WB - ABIN657828 : Ko, Lee, Shin, Karuppagounder, Gadad, Koleske, Pletnikova, Troncoso, Dawson, Dawson: Phosphorylation by the c-Abl protein tyrosine kinase inhibits parkin's ubiquitination and protective function. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)
    Zeige alle 2 Referenzen für 657828

  8. Human Polyclonal ABL1 Primary Antibody für IHC (p), WB - ABIN392078 : Donaldson, Gish, Pawson, Kay, Forman-Kay: Structure of a regulatory complex involving the Abl SH3 domain, the Crk SH2 domain, and a Crk-derived phosphopeptide. in Proceedings of the National Academy of Sciences of the United States of America 2002 (PubMed)

Weitere Antikörper gegen ABL1 Interaktionspartner

Human C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) Interaktionspartner

  1. We demonstrate that nanopore technology is suitable for employment in the hematology laboratory for detecting BCR (zeige BCR Antikörper)-ABL1 kinase domain mutation in Philadelphia-positive leukemias.

  2. Data suggest that amphipathic beta-strands in 200 N-terminal residues of beta1 domain of APOB (zeige APOB Antikörper) are required for secretion of lipid-rich or lipid-poor particles; residues 300-700 or 1050-1500 of beta1 domain appear to be required for secretion of lipid-rich particles; MTTP (zeige MTTP Antikörper) is required for secretion of intact APOB (zeige APOB Antikörper) but not of truncated APOB (zeige APOB Antikörper). (APOB (zeige APOB Antikörper) = apolipoprotein B (zeige APOB Antikörper); MTTP (zeige MTTP Antikörper) = microsomal triglyceride transfer protein (zeige MTTP Antikörper))

  3. Frequent molecular monitoring and intervention are required for patients who do not show a reduction in BCR (zeige BCR Antikörper)-ABL1 transcripts to these levels after stem cell transplantation.

  4. c-Abl promotes TGF-beta (zeige TGFB1 Antikörper)-induced SKIP/Smad3 (zeige SMAD3 Antikörper) interaction.

  5. Data indicate the feasibility of detecting ABL1 mutations in cerebrospinal fluid (CSF (zeige CSF2 Antikörper)) by next-generation sequencing (NGS) in patients with central nervous system relapse in BCR (zeige BCR Antikörper)-ABL1-positive acute lymphoblastic leukemia.

  6. the e13a2 BCR (zeige BCR Antikörper)-ABL1 fusion transcript affects the rate, the depth, and the speed of the response to treatment with imatinib firstline, and that including the transcript type in the calculation of the baseline risk scores may improve prognostic stratification and may help the choice of the best treatment policy.

  7. Normal ABL1 is a tumor suppressor in BCR (zeige BCR Antikörper)-ABL1-induced leukemia. Allosteric stimulation of the normal ABL1 kinase (zeige BCR Antikörper) activity enhanced the antileukemia effect of ABL1 tyrosine kinase inhibitors.

  8. the ABL family of tyrosine kinases rheostatically enhances IRE1alpha's enzymatic activities, thereby potentiating endoplasmic reticulum stress-induced apoptosis.

  9. 6 overexpression may contribute to the high proliferation and low apoptosis in chronic myeloid leukemia (zeige BCL11A Antikörper) cells and can be regulated by BCR/ABL signal transduction through downstream phosphoinositide 3-kinase/Akt (zeige AKT1 Antikörper) and Janus kinase/signal transducer and activator of transcription (zeige STAT1 Antikörper) pathways, suggesting cell division cycle protein 6 as a potential therapeutic target in chronic myeloid leukemia (zeige BCL11A Antikörper).

  10. ETV6 (zeige ETV6 Antikörper)-ABL1 fusion occurs in both lymphoid and myeloid leukemias; the genomic profile and clinical behavior resemble BCR (zeige BCR Antikörper)-ABL1-positive malignancies, including the unfavorable prognosis, particularly of acute leukemias. The poor outcome suggests that treatment with tyrosine kinase (zeige TXK Antikörper) inhibitors should be considered for patients with this fusion.

Mouse (Murine) C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) Interaktionspartner

  1. Normal ABL1 is a tumor suppressor in BCR (zeige BCR Antikörper)-ABL1-induced leukemia. ABL1 inhibits expansion and proliferation of BCR (zeige BCR Antikörper)-ABL1-expressing leukemic stem cells. Allosteric stimulation of the normal ABL1 kinase activity enhanced the antileukemia effect of ABL1 tyrosine kinase (zeige TYRO3 Antikörper) inhibitors.

  2. the ABL family of tyrosine kinases rheostatically enhances IRE1alpha's enzymatic activities, thereby potentiating endoplasmic reticulum stress-induced apoptosis.

  3. p38a (zeige MAPK14 Antikörper) as a major substrate of c-Abl both in vitro and in vivo and c-Abl-mediated phosphorylation is critical for the dimerization of p38a (zeige MAPK14 Antikörper).

  4. Our data show that: i) HDAC2 (zeige HDAC2 Antikörper) levels and activity are increased in NPC (zeige NPC1 Antikörper) neuronal models and in Npc1 (zeige NPC1 Antikörper)(-/-) mice; ii) inhibition of c-Abl or c-Abl deficiency prevents the increase of HDAC2 (zeige HDAC2 Antikörper) protein levels and activity in NPC (zeige NPC1 Antikörper) neuronal models

  5. The resistance in BCR (zeige BCR Antikörper)-ABL1 cells resulted either from the Y253H mutation in the BCR (zeige BCR Antikörper)-ABL1 gene or incubation in increasing concentrations of imatinib.

  6. These results reveal a new pathway in the DNA damage response wherein ABL-dependent tyrosine phosphorylation of DGCR8 (zeige DGCR8 Antikörper) stimulates the processing of selective primary miRNAs.

  7. These findings connect the EphB signaling pathway to the regulation of intestinal adenoma initiation via Abl kinase.

  8. overexpression of Id2 in primary alveolar epithelial cells promotes proliferation by inhibiting a retinoblastoma protein/c-Abl interaction leading to greater c-Abl activity.

  9. The study demonstrates a previously unrecognized mechanism that controls insulin (zeige INS Antikörper) expression through c-Abl-regulated NKx2.2 (zeige Nkx2-2 Antikörper) and GLUT2 (zeige SLC2A2 Antikörper).

  10. Oocyte-specific inactivation of Omcg1 leads to DNA damage and c-Abl/TAp63-dependent oocyte death associated with dramatic remodeling of ovarian somatic cells.

Caenorhabditis elegans (C. elegans) C-Abl Oncogene 1, Non-Receptor tyrosine Kinase (ABL1) Interaktionspartner

  1. MIG-13 (zeige DHPS Antikörper)-WAVE pathway provides the major force for directional cell motility, whereas MIG-13 (zeige DHPS Antikörper)-WASP (zeige WASL Antikörper) partially compensates for its loss, underscoring their coordinated activities in facilitating robust cell migration.

  2. By screening candidate genes involved in Eph (zeige EPHA1 Antikörper) signaling, we find that the Eph (zeige EPHA1 Antikörper) kinase-independent pathway involves the ABL-1 nonreceptor tyrosine kinase (zeige TYRO3 Antikörper) and possibly the phosphatidylinositol 3-kinase pathway

  3. The trade-off in immunological susceptibility in C. elegans is further mediated by the reciprocal activity of lys (zeige LYZ Antikörper)-7 and the tyrosine kinase abl-1.

  4. oxidative, osmotic, heat shock and starvation stresses induce germ cell apoptosis through a p53 (zeige TP53 Antikörper) and EGL-1 independent pathway; the MAPK (zeige MAPK1 Antikörper) kinases MEK-1 (zeige MAP2K1 Antikörper) and SEK-1 (zeige MAP2K4 Antikörper), and the p53 (zeige TP53 Antikörper) antagonist protein ABL-1, are essential for stress-induced germ cell apoptosis

  5. findings demonstrate that ABL-1, the C. elegans homolog of the mammalian c-Abl nonreceptor tyrosine kinase (zeige TYRO3 Antikörper) ABL1, is required for Shigella flexneri pathogenesis in nematodes

ABL1 Antigen-Profil

Beschreibung des Gens

MTP encodes the large subunit of the heterodimeric microsomal triglyceride transfer protein. Protein disulfide isomerase (PDI) completes the heterodimeric microsomal triglyceride transfer protein, which has been shown to play a central role in lipoprotein assembly. Mutations in MTP can cause abetalipoproteinemia.

Alternative names and synonyms associated with ABL1

  • c-abl oncogene 1, receptor tyrosine kinase (ABL1) Antikörper
  • c-abl oncogene 1, non-receptor tyrosine kinase (ABL1) Antikörper
  • v-abl Abelson murine leukemia viral oncogene homolog 2 (ABL2) Antikörper
  • v-abl Abelson murine leukemia viral oncogene homolog 2 (abl2) Antikörper
  • c-abl oncogene 1, non-receptor tyrosine kinase (Abl1) Antikörper
  • microsomal triglyceride transfer protein (MTTP) Antikörper
  • Protein ABL-1 (abl-1) Antikörper
  • Abl Antikörper
  • ABL1 Antikörper
  • ABLL Antikörper
  • AI325092 Antikörper
  • bcr/abl Antikörper
  • c-Abl Antikörper
  • CABL Antikörper
  • cb272 Antikörper
  • E430008G22Rik Antikörper
  • JTK7 Antikörper
  • MTP Antikörper
  • p150 Antikörper
  • v-abl Antikörper

Bezeichner auf Proteinebene für ABL1

c-abl oncogene 1, receptor tyrosine kinase , v-abl Abelson murine leukemia viral oncogene homolog 1 , Abelson murine leukemia viral (v-abl) oncogene homolog 1 , v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene) , tyrosine kinase ABL , Abelson murine leukemia viral (v-abl) oncogene homolog 2 , Abelson tyrosine-protein kinase 2 , arg, Abelson-related , tyrosine-protein kinase ABL2 , v-abl Abelson murine leukemia viral oncogene homolog 2 , arg tyrosine kinase , tyrosine-protein kinase ABL2-like , Abelson tyrosine-protein kinase 1 , bcr/c-abl oncogene protein , proto-oncogene c-Abl , proto-oncogene tyrosine-protein kinase ABL1 , tyrosine-protein kinase ABL1 , Abelson murine leukemia oncogene , abelson murine leukemia viral oncogene homolog 1 , p150 , v-abl Abelson murine leukemia oncogene 1 , v-abl Abelson murine leukemia viral oncogene 1 , microsomal triglyceride transfer protein (large polypeptide, 88kDa) , microsomal triglyceride transfer protein large subunit

GENE ID SPEZIES
280970 Bos taurus
417181 Gallus gallus
464802 Pan troglodytes
491292 Canis lupus familiaris
395410 Gallus gallus
457552 Pan troglodytes
511845 Bos taurus
570636 Danio rerio
717037 Macaca mulatta
100348328 Oryctolagus cuniculus
100463896 Ailuropoda melanoleuca
100543723 Meleagris gallopavo
100588798 Nomascus leucogenys
25 Homo sapiens
540876 Bos taurus
11350 Mus musculus
311860 Rattus norvegicus
4547 Homo sapiens
181261 Caenorhabditis elegans
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