TGFA Antikörper (C-Term)

Produktnummer ABIN967168

Produktdetails anti-TGFA Antikörper

Target: TGFA (Transforming Growth Factor, alpha (TGFA))

Bindungsspezifität: AA 73-90, C-Term

Reaktivität: Human

Wirt: Bitte anfragen

Klonalität: Polyklonal

Konjugat: Dieser TGFA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminal of human TGF (73-90 aa), different from the mouse sequence by one amino acid.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Rekonstitution: 0.2ml of distilled water will yield a concentration of 500µg/ml.

Buffer: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Lagerung: -20 °C

Referenzen für anti-TGFA Antikörper (ABIN967168)

Fallon, Reid, Kinyamu, Opole, Opole, Baratta, Korc, Endo, Duong, Nguyen, Karkehabadhi, Twardzik, Patel, Loughlin: "In vivo induction of massive proliferation, directed migration, and differentiation of neural cells in the adult mammalian brain." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 26, pp. 14686-91, (2001) (PubMed).

Details zu TGFA

Target: TGFA (Transforming Growth Factor, alpha (TGFA))

Andere Bezeichnung: TGFalpha (TGFA Produkte)

Synonyme: TFGA antikoerper, LOC100009482 antikoerper, TGF alpha antikoerper, TGFA antikoerper, wa-1 antikoerper, wa1 antikoerper, RATTGFAA antikoerper, TGFAA antikoerper, NV15606 antikoerper, si:ch211-10e8.7 antikoerper, transforming growth factor alpha antikoerper, transforming growth factor alpha L homeolog antikoerper, transforming growth factor-alpha antikoerper, transforming growth factor, alpha antikoerper, TGFA antikoerper, TGF-A antikoerper, Tgfa antikoerper, tgfa.L antikoerper, LOC100121300 antikoerper, LOC100009150 antikoerper, tgfa antikoerper

Hintergrund: Transforming growth factor alpha (TGF-) is upregulated in some human cancers. It is produced in macrophages, brain cells, and keratinocytes, and induces epithelial development. It is closely related to EGF, and can also bind to the EGF receptor with similar effects . TGF stimulates neural cell proliferation in the adult injured brain. TGF was cited in the 2001 NIH Stem Cell report to the U.S. Congress as promising evidence for the ability of adult stem cells to restore function in neurodegenerative disorders.

Pathways: NF-kappaB Signalweg, RTK Signalweg, EGFR Signaling Pathway