Purified by antigen-specific affinity chromatography.
Immunogen
Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human DUSP6(Dual specificity protein phosphatase 6)
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Furukawa, Yatsuoka, Youssef, Abe, Yokoyama, Fukushige, Soeda, Hoshi, Hayashi, Sunamura, Kobari, Horii: "Genomic analysis of DUSP6, a dual specificity MAP kinase phosphatase, in pancreatic cancer." in: Cytogenetics and cell genetics, Vol. 82, Issue 3-4, pp. 156-9, (1999) (PubMed).
Groom, Sneddon, Alessi, Dowd, Keyse: "Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase." in: The EMBO journal, Vol. 15, Issue 14, pp. 3621-32, (1996) (PubMed).
DUSP6 (Dual specificity protein phosphatase 6) inactivates MAP kinases. DUSP6 has a specificity for the ERK family and it belongs to the protein-tyrosine phosphatase family and non-receptor class dual specificity subfamily. DUSP6 contains 1 rhodanese domain and 1 tyrosine-protein phosphatase domain.