FGF23 Antikörper (Fibroblast Growth Factor 23) (AA 25-75)

Details for Product anti-FGF23 Antibody No. ABIN714461, Anbieter: Anmelden zum Anzeigen
Antigen
  • FGF23
  • ADHR
  • FGFN
  • HPDR2
  • HYPF
  • PHPTC
  • fibroblast growth factor 23
  • fgf23
  • FGF23
  • Fgf23
Epitop
AA 25-75
24
8
7
6
5
4
4
2
2
2
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
88
31
21
1
Wirt
Kaninchen
52
36
31
Klonalität
Polyklonal
Konjugat
Dieser FGF23 Antikörper ist unkonjugiert
10
8
5
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
89
79
17
8
7
7
5
5
2
2
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen KLH conjugated synthetic peptide derived from human FGF23
Isotyp IgG
Reinigung Purified by Protein A.
Andere Bezeichnung Fgf23 (FGF23 Antibody Abstract)
Hintergrund

Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Upregulates EGR1 expression in the presence of KL (By similarity). Acts directly on the parathyroid to decrease PTH secretion (By similarity). Regulator of vitamin-D metabolism. Negatively regulates osteoblast differentiation and matrix mineralization.

Subcellular location: Secreted

Synonyms: ADHR, FGFN, HYPF, HPDR2, PHPTC, Fibroblast growth factor 23, FGF-23, Phosphatonin, Tumor-derived hypophosphatemia-inducing factor, FGF23, UNQ327/PRO9828

Gen-ID 8074
UniProt Q9GZV9
Pathways RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Negative Regulation of Hormone Secretion
Applikationshinweise WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C
Haltbarkeit 12 months
Bilder des Herstellers
Immunohistochemistry (IHC) image for anti-Fibroblast Growth Factor 23 (FGF23) (AA 25-75) antibody (ABIN714461) Formalin-fixed and paraffin embedded rabbit knee tissue labeled with Anti-FGF23 Polyc...
Immunohistochemistry (IHC) image for anti-Fibroblast Growth Factor 23 (FGF23) (AA 25-75) antibody (ABIN714461) Formalin-fixed and paraffin embedded mouse embryo labeled with Anti-FGF23 Polyclonal ...
Immunohistochemistry (IHC) image for anti-Fibroblast Growth Factor 23 (FGF23) (AA 25-75) antibody (ABIN714461) Formalin-fixed and paraffin embedded human kidney labeled with Anti-FGF23 Polyclonal ...
Produkt verwendet in: Andersen, Huntley, Sandberg, Heublein, Burnett: "Elevation of circulating but not myocardial FGF23 in human acute decompensated heart failure." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, Vol. 31, Issue 5, pp. 767-72, 2016 (PubMed).

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