ACVR1 Antikörper (AA 132-161)
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- Target Alle ACVR1 (ACRV1) Antikörper anzeigen
- ACVR1 (ACRV1) (Activin Receptor Type I (ACRV1))
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Bindungsspezifität
- AA 132-161
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser ACVR1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Homologie
- B, M, Rat
- Aufreinigung
- This antibody is purified through a protein A column, followed by peptide affinity purification.
- Immunogen
- This ACVR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-161 amino acids from the Central region of human ACVR1.
- Klon
- RB33883
- Isotyp
- Ig Fraction
- Top Product
- Discover our top product ACRV1 Primärantikörper
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- Applikationshinweise
- WB: 1:1000. WB: 1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- ACVR1 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
- Haltbarkeit
- 6 months
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- Target
- ACVR1 (ACRV1) (Activin Receptor Type I (ACRV1))
- Andere Bezeichnung
- ACVR1 (ACRV1 Produkte)
- Synonyme
- ACTRI antikoerper, ACVR1A antikoerper, ACVRLK2 antikoerper, ALK2 antikoerper, FOP antikoerper, SKR1 antikoerper, TSRI antikoerper, ActR-IA antikoerper, ActR-I antikoerper, ActRIA antikoerper, Acvr antikoerper, Acvrlk2 antikoerper, Alk-2 antikoerper, Alk8 antikoerper, D330013D15Rik antikoerper, Tsk7L antikoerper, actri antikoerper, acvr1 antikoerper, acvr1-a antikoerper, acvr1-b antikoerper, acvr1a antikoerper, acvrlk2 antikoerper, alk-2 antikoerper, alk2 antikoerper, alk8 antikoerper, fop antikoerper, sax antikoerper, skr1 antikoerper, tsri antikoerper, xALK-2 antikoerper, activin A receptor type 1 antikoerper, activin A receptor, type 1 antikoerper, activin A receptor type 1 S homeolog antikoerper, ACVR1 antikoerper, Acvr1 antikoerper, acvr1.S antikoerper
- Hintergrund
- Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I ( I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. This gene encodes activin A type I receptor which signals a particular transcriptional response in concert with activin type II receptors. Mutations in this gene are associated with fibrodysplasia ossificans progressive.
- Molekulargewicht
- 57153
- Gen-ID
- 90
- NCBI Accession
- NP_001096, NP_001104537
- UniProt
- Q04771
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