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CCR5 Antikörper
CCR5
Reaktivität: Human
WB, FACS, IP, IHC (p), EIA
Wirt: Maus
Monoclonal
T21-8
unconjugated
Produktdetails anti-CCR5 Antikörper
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Target
Alle CCR5 Antikörper anzeigen
CCR5
(Chemokine (C-C Motif) Receptor 5 (CCR5))
Reaktivität
Alle Reaktivitäten für CCR5 Antikörper
Human
Wirt
Alle Wirte für CCR5 Antikörper
Maus
Klonalität
Alle Klonalitäten für CCR5 Antikörper
Monoklonal
Konjugat
Alle Konjugate für CCR5 Antikörper
Dieser CCR5 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für CCR5 Antikörper
Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Spezifität
Recognizes C-C Chemokine Receptor 5 (CCR5)
Kreuzreaktivität (Details)
Species reactivity (tested):Human.
Aufreinigung
Affinity Chromatography
Immunogen
Human CCR5
Klon
T21-8
Isotyp
IgG1
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Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
0.5 mg/mL
Buffer
Aqeous buffer containing 0.09 % Sodium Azide as preservative and may contain carrier protein/stabilizer
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Details zu CCR5
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Target
CCR5
(Chemokine (C-C Motif) Receptor 5 (CCR5))
Andere Bezeichnung
CD195 / CCR5 (CCR5 Produkte )
Synonyme
CC-CKR-5 antikoerper, CCCKR5 antikoerper, CCR-5 antikoerper, CD195 antikoerper, CKR-5 antikoerper, CKR5 antikoerper, CMKBR5 antikoerper, IDDM22 antikoerper, Ckr5 antikoerper, Cmkbr5 antikoerper, CCR1-L antikoerper, GPCR antikoerper, CCR5 antikoerper, AM4-7 antikoerper, C-C motif chemokine receptor 5 (gene/pseudogene) antikoerper, chemokine (C-C motif) receptor 5 antikoerper, C-C motif chemokine receptor 5 antikoerper, CCR5 antikoerper, Ccr5 antikoerper
Hintergrund
Human CD195 is a member of the G protein coupled superfamily of receptors, which acts as a receptor for a number of chemokines including RANTES and also serves as a co-receptor for the entry of HIV into cells. It plays a key role in regulating the activation and migration of leukocytes. CD195 is expressed by a subset of T lymphocytes and by monocytes. CD195 is rapidly phosphorylated within the C-terminal domain upon ligand stimulation. Recent studies suggest that phosphorylation at Ser337 is mediated by Protein kinase C, whereas phosphorylation at Ser349 is mediated by GPCR kinases.Synonyms: C-C CKR-5, C-C chemokine receptor type 5, CC-CKR-5, CCR-5, CHEMR13, CMKBR5, HIV-1 fusion coreceptor
Gen-ID
1234
NCBI Accession
NP_000570
UniProt
P51681
Pathways
Cellular Response to Molecule of Bacterial Origin , cAMP Metabolic Process , Regulation of Cell Size
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