COL4a3 Antikörper

Produktnummer ABIN4902585

Produktdetails anti-COL4a3 Antikörper

Target: COL4a3 (COL4A3) (Collagen, Type IV, alpha 3 (COL4A3))

Reaktivität: Human

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser COL4a3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Sequenz: RGPTEYYDTY QEK

Aufreinigung: Anti-COL4A3 antibody was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

Alpha 3 and alpha 4 type IV collagens are colocalized and present in kidney, eye, basement membranes of lens capsule, cochlea, lung, skeletal muscle, aorta, synaptic fibers, fetal kidney and fetal lung. PubMed:8083201 reports similar levels of expression of alpha 3 and alpha 4 type IV collagens in kidney, but PubMed:7523402 reports that in kidney levels of alpha 3 type IV collagen are significantly lower than those of alpha 4 type IV collagen. According to PubMed:8083201, alpha 3 type IV collagen is not detected in heart, brain, placenta, liver, pancreas, extrasynaptic muscle fibers, endoneurial and perineurial nerves, fetal brain, fetal heart and fetal liver. According to PubMed:7523402, alpha 3 type IV collagen is strongly expressed in pancreas, neuroretina and calvaria and not expressed in adrenal, ileum and skin. Isoform 1 and isoform 3 are strongly expressed in kidney, lung, suprarenal capsule, muscle and spleen, in each of these tissues isoform 1 is more abundant than isoform 3. Isoform 1 and isoform 3 are expressed at low levels in artery, fat, pericardium and peripherical nerve, but not in placenta, mesangium, skin, pleura and cultured umbilical endothelial cells.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: 0.5 mg/mL in Tris saline, with 0.5 % bovine serum albumin and 0.02 % sodium azide,  pH 7.3 .

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C, and avoid repeat freeze-thaw cycles.

Details zu COL4a3

Target: COL4a3 (COL4A3) (Collagen, Type IV, alpha 3 (COL4A3))

Andere Bezeichnung: COL4A3 (COL4A3 Produkte)

Synonyme: zTumstatin antikoerper, [a]3(IV) antikoerper, alpha3(IV) antikoerper, collagen type IV alpha 3 chain antikoerper, collagen, type IV, alpha 3 antikoerper, COL4A3 antikoerper, col4a3 antikoerper, Col4a3 antikoerper

Hintergrund: Goat polyclonal to COL4A3.

Gen-ID: 1285

UniProt: Q01955

Pathways: Sensory Perception of Sound, Positive Regulation of Endopeptidase Activity