NFAT5 Antikörper (Middle Region)

Produktnummer ABIN501747

Produktdetails anti-NFAT5 Antikörper

Target: NFAT5 (Nuclear Factor of Activated T-Cells 5, Tonicity-Responsive (NFAT5))

Bindungsspezifität: Middle Region

Reaktivität: Human, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFAT5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PGQPQNEGQP PVTTLLSQQM PENSPLASSI NTNQNIEKID LLVSLQNQGN

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against NFAT5. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NFAT5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1531 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NFAT5

Target: NFAT5 (Nuclear Factor of Activated T-Cells 5, Tonicity-Responsive (NFAT5))

Andere Bezeichnung: NFAT5 (NFAT5 Produkte)

Synonyme: zgc:63502 antikoerper, wu:fi46f11 antikoerper, TonEBP antikoerper, NFAT5 antikoerper, nfatz antikoerper, orebp antikoerper, nf-at5 antikoerper, nfatl1 antikoerper, tonebp antikoerper, DKFZp469P1514 antikoerper, AI225870 antikoerper, B130038B15Rik antikoerper, CAG-8 antikoerper, CAG80 antikoerper, NFATL1 antikoerper, OREBP antikoerper, mKIAA0827 antikoerper, NF-AT5 antikoerper, NFATZ antikoerper, TONEBP antikoerper, Nfat antikoerper, nuclear factor of activated T-cells 5 antikoerper, nuclear factor of activated T-cells 5, tonicity-responsive a antikoerper, nuclear factor of activated T-cells 5, tonicity-responsive S homeolog antikoerper, nuclear factor of activated T-cells 5, tonicity-responsive antikoerper, nuclear factor of activated T cells 5 antikoerper, NFAT5 antikoerper, nfat5a antikoerper, nfat5.S antikoerper, nfat5 antikoerper, Nfat5 antikoerper

Hintergrund: NFAT5 is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements.The product of this gene is a member of the nuclear factors of activated T cells family of transcription factors. Proteins belonging to this family play a central role in inducible gene transcription during the immune response. This protein regulates gene expression induced by osmotic stress in mammalian cells. Unlike monomeric members of this protein family, this protein exists as a homodimer and forms stable dimers with DNA elements. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: KIAA0827, NF-AT5, NFATL1, NFATZ, OREBP, TONEBP
Protein Interaction Partner: gag-pol, SUMO2, TBC1D4, NFAT5, FOXP3,
Protein Size: 1531

Molekulargewicht: 166 kDa

Gen-ID: 10725

NCBI Accession: NM_006599, NP_006590

UniProt: O94916

Pathways: RTK Signalweg, WNT Signalweg