MEF2A Antikörper (N-Term)
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- Target Alle MEF2A Antikörper anzeigen
- MEF2A (Myocyte Enhancer Factor 2A (MEF2A))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Pferd, Hund, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio), Schaf
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser MEF2A Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- GRKKIQITRI MDERNRQVTF TKRKFGLMKK AYELSVLCDC EIALIIFNSS
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against MEF2A. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human MEF2A
- Top Product
- Discover our top product MEF2A Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 507 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- MEF2A (Myocyte Enhancer Factor 2A (MEF2A))
- Andere Bezeichnung
- MEF2A (MEF2A Produkte)
- Synonyme
- ADCAD1 antikoerper, RSRFC4 antikoerper, RSRFC9 antikoerper, mef2 antikoerper, A430079H05Rik antikoerper, mef2a antikoerper, wu:fd19d02 antikoerper, adcad1 antikoerper, rsrfc4 antikoerper, rsrfc9 antikoerper, sl2 antikoerper, MEF2A antikoerper, xmef2a antikoerper, myocyte enhancer factor 2A antikoerper, myocyte enhancer factor 2aa antikoerper, myocyte enhancer factor 2a antikoerper, myocyte-specific enhancer factor 2A antikoerper, myocyte-specific enhancer factor 2a, putative antikoerper, myocyte enhancer factor 2A L homeolog antikoerper, MEF2A antikoerper, Mef2a antikoerper, mef2aa antikoerper, EDI_092490 antikoerper, EDI_038250 antikoerper, Smp_161530 antikoerper, mef2a.L antikoerper, mef2a antikoerper, LOC539054 antikoerper
- Hintergrund
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The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes 'agamous' and 'deficiens' and the human serum response factor SRF (MIM 600589)),a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain. The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD (MIM159970), myogenin (MIM 159980), MYF5 (MIM 159990), and MRF4 (MIM159991) are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes 'agamous' and 'deficiens' and the human serum response factor SRF (MIM 600589)),a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain.The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD (MIM 159970), myogenin (MIM 159980), MYF5 (MIM 159990), and MRF4 (MIM 159991) are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes 'agamous' and 'deficiens' and the human serum response factor SRF (MIM 600589)), a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ADCAD1, RSRFC4, RSRFC9, mef2
Protein Interaction Partner: HDAC7, HDAC5, HDAC3, TAF8, GNG12, TBP, GNB2, ERBB2IP, NDUFB9, DDB1, Dlg4, PHB2, ASCL1, SUMO1, UBE2I, SUMO2, HNRNPA1, UBC, MEF2D, HDAC1, EP300, HDAC4, ACTN4, THRA, HDAC9, MAPK7, CASP7, SMAD2, SMAD4, MEF2A, CASP3, MAPK14, TEAD1, MYOG, MYOD1, CDK5, VGLL4,
Protein Size: 507 - Molekulargewicht
- 55 kDa
- Gen-ID
- 4205
- NCBI Accession
- NM_005587, NP_005578
- UniProt
- Q02078
- Pathways
- Neurotrophin Signalübertragung, Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades
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