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MEF2A Antikörper (pThr312)

MEF2A Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, IP, ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6256540
  • Target Alle MEF2A Antikörper anzeigen
    MEF2A (Myocyte Enhancer Factor 2A (MEF2A))
    Bindungsspezifität
    • 19
    • 18
    • 14
    • 8
    • 7
    • 7
    • 6
    • 6
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pThr312
    Reaktivität
    • 124
    • 97
    • 78
    • 10
    • 9
    • 8
    • 8
    • 8
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Human, Maus, Ratte
    Wirt
    • 121
    • 5
    Kaninchen
    Klonalität
    • 110
    • 16
    Polyklonal
    Konjugat
    • 64
    • 8
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser MEF2A Antikörper ist unkonjugiert
    Applikation
    • 94
    • 41
    • 39
    • 32
    • 26
    • 26
    • 21
    • 12
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)
    Spezifität
    Phospho-MEF2A (Thr312) Antibody detects endogenous levels of MEF2A only when phosphorylated at Threonine 312.
    Homologie
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Aufreinigung
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    Immunogen
    A synthesized peptide derived from human MEF2A around the phosphorylation site of Thr312.
    Isotyp
    IgG
    Top Product
    Discover our top product MEF2A Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:50-1:200, IP, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20 °C. Stable for 12 months from date of receipt.
    Haltbarkeit
    12 months
  • Target
    MEF2A (Myocyte Enhancer Factor 2A (MEF2A))
    Andere Bezeichnung
    MEF2A (MEF2A Produkte)
    Synonyme
    ADCAD1 antikoerper, RSRFC4 antikoerper, RSRFC9 antikoerper, mef2 antikoerper, A430079H05Rik antikoerper, mef2a antikoerper, wu:fd19d02 antikoerper, adcad1 antikoerper, rsrfc4 antikoerper, rsrfc9 antikoerper, sl2 antikoerper, MEF2A antikoerper, xmef2a antikoerper, myocyte enhancer factor 2A antikoerper, myocyte enhancer factor 2aa antikoerper, myocyte enhancer factor 2a antikoerper, myocyte-specific enhancer factor 2A antikoerper, myocyte-specific enhancer factor 2a, putative antikoerper, myocyte enhancer factor 2A L homeolog antikoerper, MEF2A antikoerper, Mef2a antikoerper, mef2aa antikoerper, EDI_092490 antikoerper, EDI_038250 antikoerper, Smp_161530 antikoerper, mef2a.L antikoerper, mef2a antikoerper, LOC539054 antikoerper
    Hintergrund

    Description: Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT]4TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter.

    Gene: MEF2A

    Molekulargewicht
    55kDa
    Gen-ID
    4205
    UniProt
    Q02078
    Pathways
    Neurotrophin Signalübertragung, Activation of Innate immune Response, Carbohydrate Homeostasis, Chromatin Binding, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades
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