×
Aktivieren Sie Javascript in Ihrem Browser, um unsere Webseite optimal zu nutzen.
IL12A Antikörper
IL12A
Reaktivität: Human, Maus, Ratte
IHC (p)
Wirt: Kaninchen
Polyclonal
unconjugated
Produktdetails anti-IL12A Antikörper
(ausblenden)
Target
Alle IL12A Antikörper anzeigen
IL12A
(Interleukin 12 alpha (IL12A))
Reaktivität
Alle Reaktivitäten für IL12A Antikörper
Human, Maus, Ratte
Wirt
Alle Wirte für IL12A Antikörper
Kaninchen
Klonalität
Alle Klonalitäten für IL12A Antikörper
Polyklonal
Konjugat
Alle Konjugate für IL12A Antikörper
Dieser IL12A Antikörper ist unkonjugiert
Applikation
Alle Applikationen für IL12A Antikörper
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Spezifität
This antibody detects endogenous levels of IL-12A protein. (region surrounding Thr65)
Kreuzreaktivität (Details)
Species reactivity (expected):Mouse and RatSpecies reactivity (tested):Human.
Aufreinigung
Affinity chromatography
Reinheit
> 95 % by SDS-PAGE
Top Product
Discover our top product IL12A Primärantikörper
Alternativen
(anzeigen)
Anwendungsinformationen
(ausblenden)
Applikationshinweise
Immunohistochemistry: 1/50 - 1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
(ausblenden)
Konzentration
1,0 mg/mL
Buffer
PBS, pH 7.2, 0.05 % sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Details zu IL12A
(ausblenden)
Target
IL12A
(Interleukin 12 alpha (IL12A))
Andere Bezeichnung
Interleukin-12 alpha / IL12A (IL12A Produkte )
Synonyme
CLMF antikoerper, IL-12A antikoerper, NFSK antikoerper, NKSF1 antikoerper, P35 antikoerper, CLMF2 antikoerper, IL-12B antikoerper, NKSF antikoerper, NKSF2 antikoerper, p40 antikoerper, Il-12b antikoerper, Il12p40 antikoerper, Il-12p40 antikoerper, Il12 antikoerper, IL-12p40 antikoerper, IL-12p35 antikoerper, Il-12a antikoerper, Ll12a antikoerper, p35 antikoerper, IL12p35 antikoerper, Il-12 p35 antikoerper, IL12p40 antikoerper, IL12 antikoerper, IL-12 p35 antikoerper, interleukin 12A antikoerper, interleukin 12B antikoerper, interleukin 12b antikoerper, interleukin 12a antikoerper, Interleukin 12 level antikoerper, IL12A antikoerper, IL12B antikoerper, Il12b antikoerper, Il12a antikoerper, IL12 antikoerper, il12a antikoerper
Hintergrund
IL-12 is secreted by macrophages and human B-lymphoblastoid cells in response to antigenic stimulation. This IL is responsible for the differentiation of naive CD4+ T cells into type 1 helper T cells that produce interferon-γ (IFN-γ). It also activates production of tumor necrosis factor α (TNFα) from T and natural killer (NK) cells, and it inhibits IL-4 mediated suppression of IFN-γ. IL-12 also has anti-angiogenic activity since the production of IFN-γ increases the production of inducible protein-10 (IP-10). IL-12 p40 represents a subunit of IL-12 that is induced by several pathogens. IL-12 p70 is a subunit of IL-12 that is controlled through both the p35 and p40 genes in a cell type-specific fashion.Synonyms: CLMF p35, Cytotoxic lymphocyte maturation factor 35 kDa subunit, IL-12 subunit p35, IL-12A, NK cell stimulatory factor chain 1, NKSF1
Molekulargewicht
approx. 25 kDa
Gen-ID
3592
NCBI Accession
NP_000873
UniProt
P29459
Pathways
JAK-STAT Signalweg , Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Activated T Cell Proliferation
Zuletzt angesehen
(ausblenden)