Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Homologie
M, Rat
Aufreinigung
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Immunogen
This WNT4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-269 amino acids from the C-terminal region of human WNT4.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Haltbarkeit
6 months
Beyer, Schramm, Akhmetshina, Dees, Kireva, Gelse, Sonnylal, de Crombrugghe, Taketo, Distler, Schett, Distler: "?-catenin is a central mediator of pro-fibrotic Wnt signaling in systemic sclerosis." in: Annals of the rheumatic diseases, Vol. 71, Issue 5, pp. 761-7, (2012) (PubMed).
Target
WNT4
(Wingless-Type MMTV Integration Site Family, Member 4 (WNT4))
CG4698 antikoerper, DWnt-4 antikoerper, DWnt4 antikoerper, Dm DWnt4 antikoerper, Dmel\\CG4698 antikoerper, Dwnt4 antikoerper, Wnt antikoerper, Wnt-4 antikoerper, anon-EST:Liang-2.4 antikoerper, clone 2.4 antikoerper, wnt-4 antikoerper, wnt4 antikoerper, SERKAL antikoerper, WNT-4 antikoerper, Xwnt4 antikoerper, xwnt-4 antikoerper, zgc:136737 antikoerper, Wnt family member 4 antikoerper, Wnt oncogene analog 4 antikoerper, wingless-type MMTV integration site family, member 4 antikoerper, wingless-type MMTV integration site family member 4 S homeolog antikoerper, wingless-type MMTV integration site family, member 4a antikoerper, WNT4 antikoerper, Wnt4 antikoerper, wnt4.S antikoerper, wnt4a antikoerper
Hintergrund
The WNT family consists of secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT4 is a protein which shows 98 % amino acid identity to the Wnt4 protein of mouse and rat. It play a concerted role in both the control of female development and the prevention of testes formation.