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MAPK7 Antikörper (C-Term)

MAPK7 Reaktivität: Human WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN359634
  • Target Alle MAPK7 Antikörper anzeigen
    MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))
    Bindungsspezifität
    • 16
    • 16
    • 16
    • 16
    • 15
    • 15
    • 14
    • 10
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 88
    • 62
    • 56
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 119
    • 2
    • 1
    • 1
    Kaninchen
    Klonalität
    • 112
    • 11
    Polyklonal
    Konjugat
    • 42
    • 10
    • 9
    • 7
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    Dieser MAPK7 Antikörper ist unkonjugiert
    Applikation
    • 76
    • 54
    • 53
    • 43
    • 24
    • 22
    • 16
    • 13
    • 8
    • 5
    • 4
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody reacts to ERK5.
    Aufreinigung
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human ERK5.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product MAPK7 Primärantikörper
  • Applikationshinweise
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    MAPK7 (Mitogen-Activated Protein Kinase 7 (MAPK7))
    Andere Bezeichnung
    MAPK7 / ERK5 (MAPK7 Produkte)
    Synonyme
    BMK1 antikoerper, ERK4 antikoerper, ERK5 antikoerper, PRKM7 antikoerper, Erk5-T antikoerper, ATMPK7 antikoerper, F8D23.5 antikoerper, F8D23_5 antikoerper, MAP kinase 7 antikoerper, Bmk1 antikoerper, Erk5 antikoerper, Prkm7 antikoerper, ERK-5 antikoerper, bmk1 antikoerper, erk4 antikoerper, mapk7 antikoerper, prkm7 antikoerper, mitogen-activated protein kinase 7 antikoerper, MAP kinase 7 antikoerper, mitogen-activated protein kinase 7 L homeolog antikoerper, MAPK7 antikoerper, Mapk7 antikoerper, MPK7 antikoerper, mapk7.L antikoerper
    Hintergrund
    MEK5 and ERK5, a member of the MAP kinase subfamily of the Ser/Thr protein kinases, interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways. ERK5 is activated by tyrosine and threonine phosphorylation It is expressed in many adult tissues, abundantly in heart, placenta, lung, kidney and skeletal muscle, but is not detectable in liver. The second proline-rich region may interact with actin targeting the kinase to a specific location in the cell. ERK5 is autophosphorylated on threonine and tyrosine residues when the C-terminal part of the kinase, which could have a regulatory role, is absent.Synonyms: Big MAP kinase 1, ERK4, Extracellular signal-regulated kinase 5, MAPK7, Mitogen-activated protein kinase 7
    Gen-ID
    5598, 9606
    UniProt
    Q13164
    Pathways
    MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, cAMP Metabolic Process, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling
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