Protein A Chromatography, followed by peptide affinity purification.
Immunogen
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 836~866 amino acids from the center region of Human ADAMTS13.
ELISA: 1/1,000. Western blotting: 1/50-1/100. Immunohistochemistry: 1/50-1/100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) Sodium Azide as preservative.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Target
ADAMTS13
(ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13))
ADAMTS13 antikoerper, ADAM-TS13 antikoerper, ADAMTS-13 antikoerper, C9orf8 antikoerper, VWFCP antikoerper, vWF-CP antikoerper, Gm710 antikoerper, ADAM metallopeptidase with thrombospondin type 1 motif 13 antikoerper, a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13 antikoerper, ADAM metallopeptidase with thrombospondin type 1 motif, 13 antikoerper, ADAMTS13 antikoerper, Adamts13 antikoerper, adamts13 antikoerper
Hintergrund
ADAMTS13 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura.Synonyms: A disintegrin and metalloproteinase with thrombospondin motifs 13, ADAM-TS13, ADAMTS-13, C9orf8, vWF-cleaving protease, von Willebrand factor-cleaving protease