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CD79a Molecule, Immunoglobulin-Associated alpha (CD79A) (AA 202-216) Antikörper (PE)

Details zu Produkt Nr. ABIN316540, Anbieter: Anmelden zum Anzeigen
Antigen
  • CD79A
  • Ig-alpha
  • Iga
  • Igalpha
  • Ly-54
  • Ly54
  • mb-1
  • IGA
  • MB-1
  • IG-alpha
Epitop
AA 202-216
52
38
23
16
15
15
10
9
5
4
3
3
3
3
2
2
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Huhn, Pferd, Meerschweinchen, Human, Affe, Maus, Schwein, Kaninchen, Ratte (Rattus)
259
88
49
45
44
38
36
36
33
23
19
13
6
3
3
3
3
3
3
2
Wirt
Maus
176
112
4
1
Klonalität (Klon)
Monoklonal ()
Konjugat
PE
27
27
17
13
7
5
2
2
2
1
1
1
1
1
Applikation
Flow Cytometry (FACS)
135
128
69
66
57
24
23
22
6
4
4
4
3
2
2
1
1
1
1
Hersteller
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Immunogen Synthetic peptide corresponding to 202-216 amino acid sequence of human mb-1
Klon HM57
Isotyp IgG1
Spezifität This antibody recognises an epitope within the cytoplasmic domain of CD79a. CD79a, also known as mb-1, is a 45 kDa protein that is expressed by B lymphocytes during differentiation from early pre-B cell stage through to plasma cells.
Produktmerkmale Synonyms: IGA, MB1, B-Cell marker, B-cell antigen receptor complex-associated protein alpha-chain,MB-1 membrane glycoprotein, Surface IgM-associated protein, Membrane-boundimmunoglobulin-associated protein
Reinigung Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Andere Bezeichnung CD79a (CD79A Antibody Abstract)
Hintergrund The CD79a molecule associates with CD79b (B29) to form a heterodimer that is non-covalently linked to surface immunoglobulin, forming the B-cell receptor (BCR) complex. The CD79a/CD79b heterodimers are also necessary for intracellular signalling following antigen-binding to surface immunoglobulin.Synonyms: B-Cell marker, B-cell antigen receptor complex-associated protein alpha-chain, IGA, MB-1 membrane glycoprotein, MB1, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated protein
Gen-ID 973
UniProt P11912
Forschungsgebiet Stem Cells, Hematopoietic Progenitors, Adaptive Immunity, CD Antigens, Surface Receptors of Immune Cells
Applikationshinweise Flow Cytometry: use 10 μL of neat antibody to label 1x10^6 cells in 100 μL, Membranepermeabilisation is required for this application.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen Nur für Forschungszwecke einsetzbar
Rekonstitution Reconstitute with 0.25 mL distilled water
Konzentration 0.1 mg/mL
Buffer Phosphate buffered saline pH 7.4 containing 0.09 % Sodium Azide (NaN3), 1 % Bovine Serum Albumin
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C
Informationen zur Lagerung Store undiluted at 2-8 °C. DO NOT FREEZE. This product is photosensitive and should be protected from light. Should this productcontain a precipitate we recommend microcentrifugation before use.
Shelf life: One year from despatch.
Haltbarkeit 12 months
Allgemeine Veröffentlichungen Jones, Cordell, Beyers et al.: "Detection of T and B cells in many animal species using cross-reactive anti-peptide antibodies." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 150, Issue 12, pp. 5429-35, 1993 (PubMed).