Indian Hedgehog Antikörper (N-Term)

Produktnummer ABIN2782160

Produktdetails anti-Indian Hedgehog Antikörper

Target: Indian Hedgehog (IHH)

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Rind (Kuh), Ziege, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Indian Hedgehog Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: AAWGCGPGRV VGSRRRPPRK LVPLAYKQFS PNVPEKTLGA SGRYEGKIAR

Homologie: Cow: 86%, Dog: 86%, Goat: 86%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against IHH. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IHH

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 411 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Indian Hedgehog Antikörper (ABIN2782160)

Mirza, Qiao, Tateyama, Miyamoto, Xiuli, Seo: "3?-Hydroxysterol-Delta24 reductase plays an important role in long bone growth by protecting chondrocytes from reactive oxygen species." in: Journal of bone and mineral metabolism, Vol. 30, Issue 2, pp. 144-53, (2012) (PubMed).

Details zu Indian Hedgehog

Target: Indian Hedgehog (IHH)

Andere Bezeichnung: IHH (IHH Produkte)

Synonyme: BDA1 antikoerper, HHG2 antikoerper, X-hh antikoerper, Xbhh antikoerper, bhh antikoerper, bhh-a antikoerper, IHH antikoerper, ehh antikoerper, zgc:113262 antikoerper, indian hedgehog antikoerper, Indian hedgehog antikoerper, indian hedgehog S homeolog antikoerper, Indian hedgehog homolog b antikoerper, IHH antikoerper, Ihh antikoerper, ihh.S antikoerper, ihhb antikoerper

Hintergrund: IHH is an intercellular signal essential for a variety of patterning events during development. It binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. It is implicated in endochondral ossification: may regulate the balance between growth and ossification of the developing bones and induces the expression of parathyroid hormone-related protein (PTHRP).
Alias Symbols: BDA1, HHG2
Protein Interaction Partner: RHOD, HHIP, PTCH2, PTCH1,
Protein Size: 411

Molekulargewicht: 45 kDa

Gen-ID: 3549

NCBI Accession: NM_002181, NP_002172

UniProt: Q14623

Pathways: Hedgehog Signalweg