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RAGE Antikörper (N-Term)

Name: RAGE Antikörper (N-Term)
SKU: ABIN2776831
Price: 521.33 EUR
Availability: InStock

AGER Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Pferd, Schwein WB Wirt: Kaninchen Polyclonal unconjugated

WB Suggested Anti-AGER Antibody Titration: 0. (RAGE Antikörper (N-Term))

Host: Mouse Target Name: AGER Sample Tissue: Mouse Pancreas Antibody Dilution: 1ug/ml (RAGE Antikörper (N-Term))

Host: Rabbit Target Name: AGER Sample Tissue: Human MCF7 Whole Cell Antibody Dilution: 1ug/ml (RAGE Antikörper (N-Term))

Lanes : Lane 1: 10ug of hRAGE HEK-293 lysateLane 2: 10ug of mRAGE HEK-293 lysate Primary Antibody Dilution : 1:1000 Secondary Antibody : Anti-rabbit-HRP Secondary Antibody Dilution : 1:2500 Gene Name : AGER Submitted by : Barry Hudson (RAGE Antikörper (N-Term))

4 Abbildungen

Produktnummer ABIN2776831

Datenblatt (PDF)

Target Alle RAGE (AGER) Antikörper anzeigen

RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
Bindungsspezifität
19

16

16

11

11

9

8

7

4

4

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term
Reaktivität
142

81

63

7

5

4

3

2

2

1

1
Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen, Meerschweinchen, Pferd, Schwein
Wirt
136

11

4

2

1
Kaninchen
Passende Sekundärantikörper
Klonalität
130

23

1
Polyklonal
Konjugat
70

11

10

9

8

5

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2
Dieser RAGE Antikörper ist unkonjugiert
Applikation
126

66

49

34

27

26

24

11

8

8

7

3

2

1

1

1
Western Blotting (WB)

Sequenz

FLPAVGIQDE GIFRCQAMNR NGKETKSNYR VRVYQIPGKP EIVDSASELT

Spezifität

The immunizing peptide sequence is 100 % homologous to all four isoforms of AGER.

Homologie

Cow: 100%, Dog: 92%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 100%, Rat: 100%

Produktmerkmale

This is a rabbit polyclonal antibody against AGER. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung

Affinity Purified

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human AGER

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AGER Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

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AGER Reaktivität: Human, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated

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AGER Reaktivität: Human, Maus WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB25948 unconjugated

anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 206-234) antibody
AGER Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal RB21217 unconjugated

anti-Advanced Glycosylation End Product-Specific Receptor (AGER) (AA 29-59), (N-Term) antibody
AGER Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB04825-04826 unconjugated

Applikationshinweise

Optimal working dilutions should be determined experimentally by the investigator.

Kommentare

Antigen size: 342 AA

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

Lot specific

Buffer

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung

Avoid repeated freeze-thaw cycles.

Lagerung

-20 °C

Informationen zur Lagerung

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Target

RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))

Andere Bezeichnung

AGER (AGER Produkte)

Synonyme

RAGE antikoerper, AGER antikoerper, advanced glycosylation end-product specific receptor antikoerper, advanced glycosylation end product-specific receptor antikoerper, MAPK/MAK/MRK overlapping kinase antikoerper, AGER antikoerper, Ager antikoerper, LOC719012 antikoerper

Hintergrund

AGER mediates interactions of advanced glycosylation end products (AGE). These are nonenzymatically glycosylated proteins which accumulate in vascular tissue in aging and at an accelerated rate in diabetes. It is receptor for amyloid beta peptide.
Alias Symbols: MGC22357, RAGE
Protein Size: 342

Molekulargewicht

36 kDa

Gen-ID

177

NCBI Accession

NM_172197, NP_751947

UniProt

Q15109

Pathways

Carbohydrate Homeostasis, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, S100 Proteine