FECH Antikörper (Middle Region)
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- Target Alle FECH Antikörper anzeigen
- FECH (Ferrochelatase (FECH))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Zebrafisch (Danio rerio), Pferd, Saccharomyces cerevisiae
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser FECH Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- KRSEVVILFS AHSLPMSVVN RGDPYPQEVS ATVQKVMERL EYCNPYRLVW
- Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Yeast: 86%, Zebrafish: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against FECH. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human FECH
- Top Product
- Discover our top product FECH Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 423 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- FECH (Ferrochelatase (FECH))
- Andere Bezeichnung
- FECH (FECH Produkte)
- Synonyme
- AI894116 antikoerper, Fcl antikoerper, fch antikoerper, zgc:109851 antikoerper, EPP antikoerper, FCE antikoerper, CG2098 antikoerper, Dmel\\CG2098 antikoerper, GB15952 antikoerper, ferrochelatase L homeolog antikoerper, ferrochelatase antikoerper, Ferrochelatase antikoerper, ferrochelatase, mitochondrial antikoerper, ferrochelatase HemH antikoerper, ferrochelatase (predicted) antikoerper, fech.L antikoerper, hemH antikoerper, Fech antikoerper, FECH antikoerper, fech antikoerper, FeCH antikoerper, LOC409922 antikoerper, hem15 antikoerper, APH_RS01140 antikoerper
- Hintergrund
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FECH is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene.The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: EPP, FCE
Protein Interaction Partner: PPP2R1A, UBC, NEDD8, MDM2, FBXO6, gag-pol, COPS5, COPS6, CUL3, ELAVL1, MINOS1, MME, USP42, USP20, ABCB7, FECH,
Protein Size: 423 - Molekulargewicht
- 42 kDa
- Gen-ID
- 2235
- NCBI Accession
- NM_000140, NP_000131
- UniProt
- P22830
- Pathways
- Transition Metal Ion Homeostasis
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