FECH Antikörper (N-Term)

Produktnummer ABIN2777033

Der Kaninchen Polyklonal anti-FECH Antikörper wird verwendet zum Nachweis von FECH in Proben von Human und Ratte. Er wurde validiert für WB und IHC.

Kurzübersicht für FECH Antikörper (N-Term) (ABIN2777033)

Target: FECH (Ferrochelatase (FECH))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FECH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-FECH Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: FECH Antibody - N-terminal region

Sequenz: QHAQGAKPQV QPQKRYESNI RKPKTGILML NMGGPETLGD VHDFLLRLFL

Homologie: Human: 100%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against FECH. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FECH

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8100603

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu FECH

Target: FECH (Ferrochelatase (FECH))

Andere Bezeichnung: FECH

Hintergrund:

Background Information: Ferrochelatase is localized to the mitochondrion where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Defects in ferrochelatase are associated with protoporphyria.Ferrochelatase is localized to the mitochondrion where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Defects in ferrochelatase are associated with protoporphyria. Two transcript variants encoding different isoforms have been found for this gene.Ferrochelatase is localized to the mitochondrion where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Defects in ferrochelatase are associated with protoporphyria. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: Ferrochelatase

Alternative Symbols: EPP, FCE, EPP1

Protein Name: Ferrochelatase, mitochondrial

Molekulargewicht: 48 kDa

Gen-ID: 2235

NCBI Accession: NP_001012533

UniProt: Q8NAN0

Pathways: Transition Metal Ion Homeostasis