FECH Antikörper (N-Term)

Produktnummer ABIN2776936

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-FECH Antikörper wird verwendet zum Nachweis von FECH in Proben von Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio) und Saccharomyces cerevisiae. Er wurde validiert für WB.

Kurzübersicht für FECH Antikörper (N-Term) (ABIN2776936)

Target: FECH (Ferrochelatase (FECH))

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FECH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FECH Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: FECH Antibody - N-terminal region

Sequenz: LDRDLMTLPI QNKLAPFIAK RRTPKIQEQY RRIGGGSPIK IWTSKQGEGM

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 77%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against FECH. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FECH

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8100601

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-FECH Antikörper (ABIN2776936)

Miyake, Ishii, Kawashima, Kodama, Sugano, Fujimoto, Hirao: "siRNA-mediated knockdown of the heme synthesis and degradation pathways: modulation of treatment effect of 5-aminolevulinic acid-based photodynamic therapy in urothelial cancer cell lines." in: Photochemistry and photobiology, Vol. 85, Issue 4, pp. 1020-7, (2009) (PubMed).

Details zu FECH

Target: FECH (Ferrochelatase (FECH))

Andere Bezeichnung: FECH

Hintergrund:

Background Information: Ferrochelatase is localized to the mitochondrion where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Defects in ferrochelatase are associated with protoporphyria.Ferrochelatase is localized to the mitochondrion where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Defects in ferrochelatase are associated with protoporphyria. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: Ferrochelatase

Alternative Symbols: EPP, FCE, EPP1

Protein Name: Ferrochelatase, mitochondrial

Molekulargewicht: 47kDa

Gen-ID: 2235

NCBI Accession: NP_001012533

UniProt: Q8NAN0

Pathways: Transition Metal Ion Homeostasis