CD161 Antikörper (PE)
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- Target Alle CD161 (KLRB1) Antikörper anzeigen
- CD161 (KLRB1) (Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))
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Reaktivität
- Ratte
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD161 Antikörper ist konjugiert mit PE
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Applikation
- Flow Cytometry (FACS)
- Spezifität
- The mouse monoclonal antibody 10/78 recognizes CD161, an approximately 30 kDa type II transmembrane C-type lectin receptor, expressed on the plasma membrane of NK cells, dendritic cells, activated monocytes and a subset of T cells as a disulphide-linked homodimer. A common extracellular epitope on rat CD161a and b isoforms is detected.
- Kreuzreaktivität (Details)
- Rat
- Aufreinigung
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- Immunogen
- Splenic cells purified from the LEW rat
- Klon
- 10-78
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product KLRB1 Primärantikörper
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- Applikationshinweise
- Flow cytometry: Recommended dilution: 1-5 μg/mL.
- Kommentare
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The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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The immunization site of cytokine-secreting tumor cell vaccines influences the trafficking of tumor-specific T lymphocytes and antitumor efficacy against regional tumors." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 10, pp. 6025-32, (2004) (PubMed).
: "Phenotypic characterization of regulatory CD4+CD25+ T cells in rats." in: International immunology, Vol. 16, Issue 2, pp. 365-75, (2004) (PubMed).
: "CD8 alpha beta T cells are not essential to the pathogenesis of arthritis or colitis in HLA-B27 transgenic rats." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 2, pp. 1099-105, (2003) (PubMed).
: "Evaluation of the hepatic NK cell response during the early phase of Fasciola hepatica infection in rats." in: Veterinary research, Vol. 33, Issue 3, pp. 327-32, (2002) (PubMed).
: "Central nervous system microglial cell activation and proliferation follows direct interaction with tissue-infiltrating T cell blasts." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 160, Issue 11, pp. 5320-30, (1998) (PubMed).
: "Negative regulation of rat natural killer cell activity by major histocompatibility complex class I recognition." in: European journal of immunology, Vol. 26, Issue 11, pp. 2582-6, (1997) (PubMed).
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The immunization site of cytokine-secreting tumor cell vaccines influences the trafficking of tumor-specific T lymphocytes and antitumor efficacy against regional tumors." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 173, Issue 10, pp. 6025-32, (2004) (PubMed).
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- Target
- CD161 (KLRB1) (Killer Cell Lectin-Like Receptor Subfamily B, Member 1 (KLRB1))
- Andere Bezeichnung
- CD161 (KLRB1 Produkte)
- Synonyme
- NKR-P1 antikoerper, KLRB1 antikoerper, 4930431A04Rik antikoerper, Gm4696 antikoerper, Klrb1g antikoerper, Klrb6 antikoerper, Ly-55 antikoerper, Ly55 antikoerper, NKR-P1G antikoerper, Nkrp-1e antikoerper, Nkrp1g antikoerper, CD161 antikoerper, CLEC5B antikoerper, NKR antikoerper, NKR-P1A antikoerper, NKRP1A antikoerper, hNKR-P1A antikoerper, Klrb1d antikoerper, Klrb1f antikoerper, Nkr-p1e antikoerper, killer cell lectin like receptor B1 antikoerper, killer cell lectin-like receptor subfamily B member 1 antikoerper, killer cell lectin-like receptor subfamily B, member 1 antikoerper, KLRB1 antikoerper, Klrb1 antikoerper
- Hintergrund
- Killer cell lectin-like receptor subfamily B, memb,CD161, also known as Nkrp1 (natural killer receptor protein 1) or Klrb1 (killer cell lectin-like receptor subfamily b member 1), is a disulphide-linked homodimeric receptor, which is involved in regulation of NK cell and NKT cell function. It is expressed on rat NK cells, subset of T cells, dendritic cells, and activated monocytes. Although human CD161 is expressed as one isoform, the rat CD161 has three isoforms, referred to as CD161a, b, and c. These proteins contain C-terminal C-type lectin extracellular domain, a transmembrane domain, and N-terminal intracellular domain, which contains ITIM motif, such as CD161b, and displays inhibitory function, or does not contain ITIM motif, thus also not the inhibitory function, such as CD161a.,NKRP1A, Klrb
- Gen-ID
- 689817
- UniProt
- Q0ZUP0
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