PHLDA3 Antikörper (N-Term)

Produktnummer ABIN2452076

Produktdetails anti-PHLDA3 Antikörper

Target: PHLDA3 (Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3))

Bindungsspezifität: AA 1-31, N-Term

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PHLDA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: Specific to human PHLDA3.

Kreuzreaktivität (Details): Not tested in other species.

Produktmerkmale: The antibody was produced from the hybridoma cultured in serum-free medium and purified under mild conditions by propriety chromatography processes.

Aufreinigung: Purified

Sterilität: Sterile filtered

Immunogen: Synthetic peptide corresponding to N terminal aa 1-31 of human PHLDA3

Klon: 4B6

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Other applications were not tested.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol

Konservierungsmittel: Azide free

Lagerung: -20 °C/-80 °C

Informationen zur Lagerung: -20 C (For long term storage: -70 C)

Referenzen für anti-PHLDA3 Antikörper (ABIN2452076)

Kawase, Ohki, Shibata, Tsutsumi, Kamimura, Inazawa, Ohta, Ichikawa, Aburatani, Tashiro, Taya: "PH domain-only protein PHLDA3 is a p53-regulated repressor of Akt." in: Cell, Vol. 136, Issue 3, pp. 535-50, (2009) (PubMed).

Details zu PHLDA3

Target: PHLDA3 (Pleckstrin Homology-Like Domain, Family A, Member 3 (PHLDA3))

Andere Bezeichnung: PHLDA3 (PHLDA3 Produkte)

Synonyme: TIH1 antikoerper, Tih1 antikoerper, si:dz182n13.5 antikoerper, zgc:92333 antikoerper, pleckstrin homology like domain family A member 3 antikoerper, pleckstrin homology like domain, family A, member 3 antikoerper, pleckstrin homology-like domain, family A, member 3 antikoerper, PHLDA3 antikoerper, Phlda3 antikoerper, phlda3 antikoerper

Hintergrund: PHLDA3 (Pleckstrin homology-like domain family A member 3) is a small PH (Pleckstrin homology) domain-only protein (127 a.a. in human) that is highly conserved in vertebrates. Recently PHLDA3 was found to be a p53-regulated repressor of Akt hence it is speculated as a tumor suppressor. PHLDA3 also inhibits anchorage-independent cell growth. PHLDA3 gene is frequently lost in human lung endocrine tumors.

UniProt: Q9Y5J5