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Cyclin B1 Antikörper (pSer35)

Name: Cyclin B1 Antikörper (pSer35)
SKU: ABIN1881155
Price: 445.5 EUR
Availability: InStock

CCNB1 Reaktivität: Human WB, DB Wirt: Kaninchen Polyclonal RB42141 unconjugated

Western blot analysis of lysate from Hela cells(from left to right),untreated or treated with Nocodazole at 50 ng/mL,using Phospho-CCNB1-S35 Antibody (ABIN1881155 and ABIN2839973) or CCNB1-S9 Antibody.

Dot blot analysis of CCNB1 Antibody (Phospho S35) Phospho-specific Pab (ABIN1881155 and ABIN2839973) on nitrocellulose membrane.

2 Abbildungen

(3 Referenzen)

Produktnummer ABIN1881155

Datenblatt (PDF)

Target Alle Cyclin B1 (CCNB1) Antikörper anzeigen

Cyclin B1 (CCNB1)
Bindungsspezifität
23

23

23

16

9

7

7

7

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
pSer35
Reaktivität
201

95

62

20

16

16

5

4

4

3

3

3

3

1

1

1
Human
Wirt
161

47

1
Kaninchen
Passende Sekundärantikörper
Klonalität
155

54
Polyklonal
Konjugat
110

10

7

6

6

6

6

6

6

6

6

4

4

4

4

4

2

2

2

2

2

2

2
Dieser Cyclin B1 Antikörper ist unkonjugiert
Applikation
139

75

57

48

41

40

39

31

30

11

11

11

10

8

4

3

3

2

1

1

1
Western Blotting (WB), Dot Blot (DB)

Aufreinigung

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This CCNB1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S35 of human CCNB1.

Klon

RB42141

Isotyp

Ig Fraction

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Applikationshinweise

WB: 1:1100. DB: 1:500

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Haltbarkeit

6 months
Kreis, Sanhaji, Krämer, Sommer, Rödel, Strebhardt, Yuan: "Restoration of the tumor suppressor p53 by downregulating cyclin B1 in human papillomavirus 16/18-infected cancer cells." in: Oncogene, Vol. 29, Issue 41, pp. 5591-603, (2010) (PubMed).

van Zon, Ogink, ter Riet, Medema, te Riele, Wolthuis: "The APC/C recruits cyclin B1-Cdk1-Cks in prometaphase before D box recognition to control mitotic exit." in: The Journal of cell biology, Vol. 190, Issue 4, pp. 587-602, (2010) (PubMed).

Harley, Allan, Sanderson, Clarke: "Phosphorylation of Mcl-1 by CDK1-cyclin B1 initiates its Cdc20-dependent destruction during mitotic arrest." in: The EMBO journal, Vol. 29, Issue 14, pp. 2407-20, (2010) (PubMed).
Target

Cyclin B1 (CCNB1)

Andere Bezeichnung

CCNB1 (CCNB1 Produkte)

Synonyme

ccnb antikoerper, cycb antikoerper, cb267 antikoerper, cycb1 antikoerper, wu:fa19g04 antikoerper, wu:fb16d01 antikoerper, wu:fb16e07 antikoerper, wu:fi21c01 antikoerper, ccnb1 antikoerper, MGC53596 antikoerper, CCNB antikoerper, Ccnb1-rs1 antikoerper, Ccnb1-rs13 antikoerper, CycB1 antikoerper, Cycb-4 antikoerper, Cycb-5 antikoerper, Cycb1-rs1 antikoerper, cyclin B1 antikoerper, cyclin B1 S homeolog antikoerper, ccnb1 antikoerper, ccnb1.2 antikoerper, ccnb1.S antikoerper, CCNB1 antikoerper, Ccnb1 antikoerper, ccnb1.2.S antikoerper

Hintergrund

The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. [provided by RefSeq].

Molekulargewicht

48337

NCBI Accession

NP_114172

UniProt

P14635

Pathways

Zellzyklus, AMPK Signaling, Mitotic G1-G1/S Phases, M Phase