TFEB Antikörper (C-Term)

Produktnummer ABIN183717

Produktdetails anti-TFEB Antikörper

Target: TFEB (Transcription Factor EB (TFEB))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Ziege, Kaninchen, Meerschweinchen, Saccharomyces cerevisiae, Schaf, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TFEB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SLSKKDLDLM LLDDSLLPLA SDPLLSTMSP EASKASSRRS SFSMEEGDVL

Homologie: Cow: 100%, Dog: 100%, Goat: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 85%, Yeast: 100%, Zebrafish: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against TFEB. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human TFEB

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 476 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TFEB

Target: TFEB (Transcription Factor EB (TFEB))

Andere Bezeichnung: TFEB (TFEB Produkte)

Synonyme: TFEB antikoerper, tcfeb antikoerper, MGC145796 antikoerper, alphatfeb antikoerper, ALPHATFEB antikoerper, BHLHE35 antikoerper, TCFEB antikoerper, Tcfeb antikoerper, bHLHe35 antikoerper, transcription factor EB antikoerper, TFEB antikoerper, tfeb antikoerper, Tfeb antikoerper

Hintergrund: TFEB is a member of the basic Helix-Loop-Helix-Zipper family of transcription factors. TFEB can bind DNA as a homodimer or as a heterodimer with three closely related family members: MITF, TFE3 and TFEC. The t(6,11)(p21,q12), a translocation recently been shown to result in fusion of Alpha, a gene on 11q12, with the transcription factor gene TFEB on 6p21.This translocation ultimately leads to the development of Renal carcinomas.
Alias Symbols: TCFEB, BHLHE35, ALPHATFEB
Protein Interaction Partner: SRPK1, YWHAQ, TFEC, TFE3, MITF,
Protein Size: 476

Molekulargewicht: 53 kDa

Gen-ID: 7942

NCBI Accession: NM_007162, NP_009093

UniProt: P19484