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TFEB Antikörper (AA 271-300)

TFEB Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB39331 unconjugated
Produktnummer ABIN1538221
  • Target Alle TFEB Antikörper anzeigen
    TFEB (Transcription Factor EB (TFEB))
    Bindungsspezifität
    • 16
    • 9
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 271-300
    Reaktivität
    • 64
    • 30
    • 26
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 57
    • 6
    • 1
    Kaninchen
    Klonalität
    • 57
    • 6
    Polyklonal
    Konjugat
    • 39
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TFEB Antikörper ist unkonjugiert
    Applikation
    • 45
    • 31
    • 14
    • 13
    • 13
    • 13
    • 10
    • 9
    • 8
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Homologie
    M
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This TFEB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 271-300 amino acids from the Central region of human TFEB.
    Klon
    RB39331
    Isotyp
    Ig Fraction
  • Applikationshinweise
    WB: 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    TFEB Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.
    Haltbarkeit
    6 months
  • Target
    TFEB (Transcription Factor EB (TFEB))
    Andere Bezeichnung
    TFEB (TFEB Produkte)
    Synonyme
    TFEB antikoerper, tcfeb antikoerper, MGC145796 antikoerper, alphatfeb antikoerper, ALPHATFEB antikoerper, BHLHE35 antikoerper, TCFEB antikoerper, Tcfeb antikoerper, bHLHe35 antikoerper, transcription factor EB antikoerper, TFEB antikoerper, tfeb antikoerper, Tfeb antikoerper
    Hintergrund
    Transcription factor that specifically recognizes and binds E-box sequences (3'-CANNTG-5'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes and binds the CLEAR-box sequence (5'-GTCACGTGAC-3') present in the regulatory region of many lysosomal genes, leading to activate their expression. It thereby plays a central role in expression of lysosomal genes. Specifically recognizes the gamma-E3 box, a subset of E-boxes, present in the heavy-chain immunoglobulin enhancer. Plays a role in the signal transduction processes required for normal vascularization of the placenta.
    Molekulargewicht
    52865
    Gen-ID
    7942
    NCBI Accession
    NP_001161299, NP_001258872, NP_001258873, NP_001258874, NP_009093
    UniProt
    P19484
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