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SMAD7 Antikörper (N-Term)

SMAD7 Reaktivität: Human, Maus, Ratte, Schwein, Rind (Kuh), Hund, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN182475
  • Target Alle SMAD7 Antikörper anzeigen
    SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
    Bindungsspezifität
    • 17
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 46
    • 26
    • 24
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    Human, Maus, Ratte, Schwein, Rind (Kuh), Hund, Kaninchen
    Wirt
    • 39
    • 7
    Kaninchen
    Klonalität
    • 40
    • 6
    Polyklonal
    Konjugat
    • 29
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser SMAD7 Antikörper ist unkonjugiert
    Applikation
    • 26
    • 17
    • 14
    • 14
    • 10
    • 8
    • 8
    • 4
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    EEEGAGGGGG GGELRGEGAT DSRAHGAGGG GPGRAGCCLG KAVRGAKGHH
    Homologie
    Cow: 93%, Dog: 93%, Human: 100%, Mouse: 92%, Pig: 93%, Rabbit: 93%, Rat: 85%
    Produktmerkmale
    This is a rabbit polyclonal antibody against SMAD7. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human SMAD7
    Top Product
    Discover our top product SMAD7 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 426 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    SMAD7 (SMAD, Mothers Against DPP Homolog 7 (SMAD7))
    Andere Bezeichnung
    SMAD7 (SMAD7 Produkte)
    Synonyme
    CRCS3 antikoerper, MADH7 antikoerper, MADH8 antikoerper, Smad7a antikoerper, Madh7 antikoerper, Smad10 antikoerper, madh7 antikoerper, xsmad7 antikoerper, wu:fj60c10 antikoerper, SMAD family member 7 antikoerper, SMAD family member 7 L homeolog antikoerper, SMAD7 antikoerper, Smad7 antikoerper, smad7.L antikoerper, smad7 antikoerper
    Hintergrund
    Smad7 acts to functionally inactivate RB and de-repress E2F without blocking the activation of TbetaRI and the nuclear translocation of Smad2/3, allowing TGF-beta1 to exert effects in a cancer cell that is resistant to TGF-beta1-mediated growth inhibition.
    Alias Symbols: CRCS3, MADH7, MADH8
    Protein Interaction Partner: HDAC3, HDAC2, USP11, SMURF2, SMURF1, SKP2, MYC, Melk, HCVgp1, RNF111, KDM2A, SOX13, PIAS1, SOX7, UBE2O, MKL2, ASH1L, PIAS4, CXXC5, ZNF107, ZBTB11, HEYL, TTF2, UBC, TTF1, SOX5, MYOD1, XRCC6, CTNNB1, MAPK14, BAMBI, PPP1R15A, NEDD4L, STAMBP, YAP1, AXIN1, TP5
    Protein Size: 426
    Molekulargewicht
    46 kDa
    Gen-ID
    4092
    NCBI Accession
    NM_005904, NP_005895
    UniProt
    O15105
    Pathways
    Interferon-gamma Pathway, Cell-Cell Junction Organization
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