C5AR1 Antikörper (N-Term)

Produktnummer ABIN181855

Produktdetails anti-C5AR1 Antikörper

Target: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Bindungsspezifität: AA 1-31, N-Term

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser C5AR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: This antibody recognises the C5a receptor (C5aR) CD88. Clone P12/1 was raised against a synthetic peptide comprising the N-terminal extracellular domain of the C5aR (met1-Asn31). Clone P12/1 does not inhibit the binding of C5a to its receptor. We recommend the use of SM1182A for functional studies.

Aufreinigung: Affinity Chromatography on Protein G

Immunogen: C5aR - peptide: Met1 - Asn31. Spleen cells from immunised BALB/c mice were fused with cells of the X63-Ag8 myeloma cell line.

Klon: P12-1

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Western Blot. Immunohistochemistry on frozen section. Immunohistochemistry on paraffin section. Flow Cytometry: 1/50 - 1/100, Use 10 μL of the suggested working dilution to label 5 x 10e5 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu C5AR1

Target: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Andere Bezeichnung: CD88 / C5R1 (C5AR1 Produkte)

Synonyme: C5A antikoerper, C5AR antikoerper, C5R1 antikoerper, CD88 antikoerper, C5aR antikoerper, C5r1 antikoerper, Cd88 antikoerper, D7Msu1 antikoerper, GPR77 antikoerper, complement C5a receptor 1 antikoerper, complement component 5a receptor 1 antikoerper, C5AR1 antikoerper, C5ar1 antikoerper, c5ar1 antikoerper

Hintergrund: C5a Anaphylatoxin Receptor mediates the effects of one of the most potent chemotactic agents known, in a wide variety of inflammatory cell types. C5a receptor 1 has been implicated in asthma. CD88 is predominantly expressed on cells of the myeloid lineage.Synonyms: C5AR1, C5a anaphylatoxin chemotactic receptor, C5a-R, C5aR, Complement Component 5a Receptor 1

Gen-ID: 728

NCBI Accession: NP_001727

UniProt: P21730

Pathways: Komplementsystem