C5AR1 Antikörper (AA 250-350)
Kurzübersicht für C5AR1 Antikörper (AA 250-350) (ABIN6137777)
Target
Alle C5AR1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 250-350
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Sequenz
- SFFIFWLPYQ VTGIMMSFLE PSSPTFLLLN KLDSLCVSFA YINCCINPII YVVAGQGFQG RLRKSLPSLL RNVLTEESVV RESKSFTRST VDTMAQKTQA V
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 250-350 of human C5AR1 (NP_001727.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- C5AR1 (Complement Component 5a Receptor 1 (C5AR1))
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Andere Bezeichnung
- C5AR1
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Hintergrund
- Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N-terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production.,C5AR1,C5A,C5AR,C5R1,CD88,Cancer,Signal Transduction,G protein signaling,G-Protein-Coupled Receptors(GPCR),Endocrine & Metabolism,Immunology & Inflammation,CD markers,Cell Intrinsic Innate Immunity Signaling Pathway,C5AR1
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Molekulargewicht
- 39 kDa
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Gen-ID
- 728
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UniProt
- P21730
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Pathways
- Komplementsystem
Target
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