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HHATL Antikörper (AA 25-125) (HRP)

HHATL Reaktivität: Human WB, ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal HRP
Produktnummer ABIN1712346
  • Target Alle HHATL Antikörper anzeigen
    HHATL (Hedgehog Acyltransferase-Like (HHATL))
    Bindungsspezifität
    • 14
    • 2
    • 1
    AA 25-125
    Reaktivität
    • 17
    • 2
    • 2
    Human
    Wirt
    • 16
    • 1
    Kaninchen
    Klonalität
    • 16
    • 1
    Polyklonal
    Konjugat
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HHATL Antikörper ist konjugiert mit HRP
    Applikation
    • 16
    • 13
    • 13
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Homologie
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human HHATL/GUP1
    Isotyp
    IgG
    Top Product
    Discover our top product HHATL Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handhabung
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    HHATL (Hedgehog Acyltransferase-Like (HHATL))
    Andere Bezeichnung
    HHATL/GUP1 (HHATL Produkte)
    Synonyme
    Gup1 antikoerper, RGD1311911 antikoerper, gup1 antikoerper, oact3 antikoerper, mboat3 antikoerper, MGC53261 antikoerper, mstp002 antikoerper, MGC89797 antikoerper, GUP1 antikoerper, 1110011D13Rik antikoerper, C3orf3 antikoerper, MBOAT3 antikoerper, MSTP002 antikoerper, OACT3 antikoerper, c3orf3b antikoerper, gup1b antikoerper, im:7145545 antikoerper, wu:fc04e05 antikoerper, zgc:154131 antikoerper, c3orf3a antikoerper, gup1a antikoerper, zgc:77750 antikoerper, hedgehog acyltransferase-like antikoerper, hedgehog acyltransferase like S homeolog antikoerper, hedgehog acyltransferase like antikoerper, hedgehog acyltransferase like, b antikoerper, hedgehog acyltransferase like, a antikoerper, Hhatl antikoerper, hhatl.S antikoerper, HHATL antikoerper, hhatl antikoerper, hhatlb antikoerper, hhatla antikoerper
    Hintergrund

    Synonyms: C3orf3, Glycerol uptake/transporter homolog, GUP1, GUP1 glycerol uptake/transporter homolog, Hedgehog acyltransferase like, Hedgehog acyltransferase-like protein, Hhatl, HHATL_HUMAN, KIAA1173, MBOAT3, Membrane bound O acyltransferase domain containing 3, MSTP002, OACT3, Protein-cysteine N-palmitoyltransferase HHAT-like protein.

    Background: GUP1 is a 504 amino acid multipass membrane protein of the endoplasmic reticulum that functions as a membrane bound O-acyltransferase. With specific expression in heart, GUP1 negatively regulates amino-terminal palmitoylation of Shh by HHAT, a protein that is required for Shh signaling. Deletion of the gene encoding GUP1 results in higher sensibility to specific sphinogolipid biosynthesis inhibitors and resistance to ergosterol biosynthesis inhibitors, indicating that GUP1 is an essential component in lipid metabolism. Also, GUP1 also seems to be important for cell wall assembly and stability due to evidence in Saccharomyces cerevisiae GUP1 mutants, which exhibit altered plasma membrane lipid composition and membrane potential.

    Gen-ID
    57467
    Pathways
    Hedgehog Signalweg
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