HHATL Antikörper (N-Term)

Produktnummer ABIN1450142

Produktdetails anti-HHATL Antikörper

Target: HHATL (Hedgehog Acyltransferase-Like (HHATL))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HHATL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid synthetic peptide near the amino terminus of Human HHATL

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu HHATL

Target: HHATL (Hedgehog Acyltransferase-Like (HHATL))

Andere Bezeichnung: GUP1 / HHATL (HHATL Produkte)

Synonyme: Gup1 antikoerper, RGD1311911 antikoerper, gup1 antikoerper, oact3 antikoerper, mboat3 antikoerper, MGC53261 antikoerper, mstp002 antikoerper, MGC89797 antikoerper, GUP1 antikoerper, 1110011D13Rik antikoerper, C3orf3 antikoerper, MBOAT3 antikoerper, MSTP002 antikoerper, OACT3 antikoerper, c3orf3b antikoerper, gup1b antikoerper, im:7145545 antikoerper, wu:fc04e05 antikoerper, zgc:154131 antikoerper, c3orf3a antikoerper, gup1a antikoerper, zgc:77750 antikoerper, hedgehog acyltransferase-like antikoerper, hedgehog acyltransferase like S homeolog antikoerper, hedgehog acyltransferase like antikoerper, hedgehog acyltransferase like, b antikoerper, hedgehog acyltransferase like, a antikoerper, Hhatl antikoerper, hhatl.S antikoerper, HHATL antikoerper, hhatl antikoerper, hhatlb antikoerper, hhatla antikoerper

Hintergrund: The Protein-cysteine N-palmitoyltransferase HHAT-like protein (HHATL), also known at the mammalian glycerol uptake/transporter 1 (Gup1) is a homolog of the S. cerevisiae Gup1. It is an endoplasmic reticulum (ER) membrane protein that co-localizes with the mammalian hedgehog acyltransferse Skn and interferes with its N-terminal palmitoylation of Sonic hedgehog (SHH), suggesting that HHATL acts as a negative regulator for N-terminal palmitoylation of SHH. HHATL is highly expressed in normal skin, but becomes down-regulated in skin squamous cell carcinoma, suggesting it may play a role in its development .Synonyms: C3orf3, Glycerol uptake/transporter homolog, Hedgehog acyltransferase-like protein, KIAA1173, Protein-cysteine N-palmitoyltransferase HHAT-like protein

Gen-ID: 57467

NCBI Accession: NP_065758

Pathways: Hedgehog Signalweg