Cyclin B1 Antikörper (pSer126)
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- Target Alle Cyclin B1 (CCNB1) Antikörper anzeigen
- Cyclin B1 (CCNB1)
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Bindungsspezifität
- AA 120-131, pSer126
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Cyclin B1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Kreuzreaktivität
- Ratte (Rattus), Hund, Schimpanse, Maus, Hamster
- Produktmerkmale
- Concentration Definition: by UV absorbance at 280 nm
- Immunogen
- This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 120-131 of Human Cyclin B1 protein.
- Isotyp
- IgG
- Top Product
- Discover our top product CCNB1 Primärantikörper
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- Applikationshinweise
- This affinity purified antibody has been tested for use in ELISA and western blot. Specific conditions for reactivity should be optimized by the end user. Expect a band ~ 48 kDa in size corresponding to Cyclin B1 by western blotting in the appropriate cell lysate or extract.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 2.01 mg/mL
- Buffer
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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Artemis links ATM to G2/M checkpoint recovery via regulation of Cdk1-cyclin B." in: Molecular and cellular biology, Vol. 27, Issue 7, pp. 2625-35, (2007) (PubMed).
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Artemis links ATM to G2/M checkpoint recovery via regulation of Cdk1-cyclin B." in: Molecular and cellular biology, Vol. 27, Issue 7, pp. 2625-35, (2007) (PubMed).
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- Target
- Cyclin B1 (CCNB1)
- Andere Bezeichnung
- Cyclin B1 (CCNB1 Produkte)
- Synonyme
- ccnb antikoerper, cycb antikoerper, cb267 antikoerper, cycb1 antikoerper, wu:fa19g04 antikoerper, wu:fb16d01 antikoerper, wu:fb16e07 antikoerper, wu:fi21c01 antikoerper, ccnb1 antikoerper, MGC53596 antikoerper, CCNB antikoerper, Ccnb1-rs1 antikoerper, Ccnb1-rs13 antikoerper, CycB1 antikoerper, Cycb-4 antikoerper, Cycb-5 antikoerper, Cycb1-rs1 antikoerper, cyclin B1 antikoerper, cyclin B1 S homeolog antikoerper, ccnb1 antikoerper, ccnb1.2 antikoerper, ccnb1.S antikoerper, CCNB1 antikoerper, Ccnb1 antikoerper, ccnb1.2.S antikoerper
- Hintergrund
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Cyclin B1 (also called CCNB1 and G2/mitotic-specific cyclin B1) is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form a serine/threonine kinase holoenzyme complex called the maturation-promoting factor (MPF). Two alternative transcripts have been found a constitutively expressed transcript and a cell cycle-regulated transcript that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. S126 phosphorylation, the site of phosphorylation recognized by this antibody, is involved in an auto-phosphorylation of the cdk -cyclin complex. Recognition of this phosphorylated site suggests the antibody is useful to detect the active form of the complex and may serve as a marker of mitosis.
Synonyms: Cyclin B1, CCNB1, CCNB, G2/mitotic-specific cyclin-B1 - Gen-ID
- 891
- UniProt
- P14635
- Pathways
- Zellzyklus, AMPK Signaling, Mitotic G1-G1/S Phases, M Phase
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