TNFRSF10A Antikörper (PE)

Produktnummer ABIN1106162

Produktdetails anti-TNFRSF10A Antikörper (PE)

Target: TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TNFRSF10A Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Spezifität: This antibody recognises CD261, a 43-46 kDa protein.

Aufreinigung: Ion Exchange Chromatography

Immunogen: Recombinant Human TRAIL R1/Fc chimera.

Klon: B-N36

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Rekonstitution: Restore with 1.0 mL deionised water.

Buffer: Phosphate-buffered saline (PBS), 0.09 % Sodium Azide, 1 % BSA

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: DO NOT FREEZE!

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu TNFRSF10A

Target: TNFRSF10A (Tumor Necrosis Factor Receptor Superfamily, Member 10a (TNFRSF10A))

Andere Bezeichnung: CD261 / TRAILR1 (TNFRSF10A Produkte)

Synonyme: APO2 antikoerper, CD261 antikoerper, DR4 antikoerper, TRAILR-1 antikoerper, TRAILR1 antikoerper, TNFRSF10A antikoerper, TNF receptor superfamily member 10a antikoerper, tumor necrosis factor receptor superfamily member 26 antikoerper, tumor necrosis factor receptor superfamily, member 10a antikoerper, TNFRSF10A antikoerper, LOC510798 antikoerper

Hintergrund: Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel death domain containing receptor was recently identified and designated DR4 (for death receptor 4)1. The ligand for this novel death receptor has been identified and termed TRAIL, which is a new member in the TNF family. DR4 is also called TRAIL receptor-1 (TRAIL-R1). DR4 is expressed in most of human tissues including spleen, peripheral blood leukocytes, small intestine and thymus. Like TNFR1, Fas and DR3, DR4 mediates apoptosis and NF-kB activation in many tissues and cells.Synonyms: APO2, DR4, Death receptor 4, TNF-related apoptosis-inducing ligand receptor 1, TNFRSF10A, TRAIL receptor 1, TRAIL-R1, Tumor necrosis factor receptor superfamily member 10A

Gen-ID: 8797

NCBI Accession: NP_003835

UniProt: O00220

Pathways: Apoptose, Positive Regulation of Endopeptidase Activity