anti-serpin Peptidase Inhibitor, Clade D (Heparin Cofactor), Member 1 (SERPIND1) Antikörper

The product encoded by SERPIND1 is a serine proteinase inhibitor which rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. Zusätzlich bieten wir Ihnen serpin Peptidase Inhibitor, Clade D (Heparin Cofactor), Member 1 Kits (46) und serpin Peptidase Inhibitor, Clade D (Heparin Cofactor), Member 1 Proteine (17) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
SERPIND1 3053 P05546
SERPIND1 79224 Q64268
SERPIND1 15160 P49182
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Top anti-serpin Peptidase Inhibitor, Clade D (Heparin Cofactor), Member 1 Antikörper auf antikoerper-online.de

Showing 10 out of 64 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-SERPIND1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>THP-1 cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue, using Heparin Cofactor II Antibody. The picture on the right is treated with the synthesized peptide. Immunofluorescence analysis of HepG2 cells, using Heparin Cofactor II Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 6 bis 8 Tage
342,86 €
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 18 bis 20 Tage
187,50 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Details
Human Maus Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 18 bis 20 Tage
250,00 €
Details
Maus Kaninchen Unkonjugiert ELISA, IP, WB   100 μg Anmelden zum Anzeigen 18 bis 20 Tage
312,50 €
Details
Human Kaninchen Unkonjugiert ELISA, IF, IHC, WB   100 μL Anmelden zum Anzeigen 13 Days
154,33 €
Details
Maus Kaninchen Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 18 bis 20 Tage
187,50 €
Details
Human Maus Unkonjugiert IHC (p) Immunochemical staining of human serpinD1 in human hepatoma with mouse monoclonal antibody (15 µg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to hepatocyte. Immunochemical staining of human serpinD1 in human liver with mouse monoclonal antibody (15 µg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to hepatocyte. 100 μg Anmelden zum Anzeigen 18 bis 20 Tage
250,00 €
Details
Human Kaninchen Unkonjugiert IHC (p) Immunochemical staining of human serpinD1 in human hepatoma with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to hepatocyte. Immunochemical staining of human serpinD1 in human liver with rabbit monoclonal antibody (5 µg/mL, formalin-fixed paraffin embedded sections). Positive staining was localized to hepatocyte. 100 μg Anmelden zum Anzeigen 18 bis 20 Tage
312,50 €
Details

SERPIND1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Rat (Rattus) , ,


Mouse (Murine) , ,

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Weitere Antikörper gegen serpin Peptidase Inhibitor, Clade D (Heparin Cofactor), Member 1 Interaktionspartner

Human serpin Peptidase Inhibitor, Clade D (Heparin Cofactor), Member 1 (SERPIND1) Interaktionspartner

  1. The plasma level of alpha2M was found positively correlated, while HCII level was negatively correlated with higher vulnerability of carotid plaques. Both proteins were efficient in differentiating stable and vulnerable carotid plaques. These provide potential new targets for the research of carotid plaque vulnerability. Plasma alpha2M and HCII may be potential biomarkers for evaluation of the vulnerability of carotid ...

  2. We found that SERPIND1 may act as a potential oncogene (zeige RAB1A Antikörper) in the development of ovarian cancer

  3. Molecular modelling of HCII 1-75 predicted those portions of the acidic extension that had been previously visualized in crystal structures, and suggested that an alpha-helix found between residues 26 and 36 stabilizes one found between residues 61-67.

  4. In this study, we demonstrate a previously unknown role for HCII in host defense.

  5. HCII potentiates the activation of vascular endothelial cells and the promotion of angiogenesis in response to hindlimb ischemia via an AMPK (zeige PRKAA1 Antikörper)-eNOS (zeige NOS3 Antikörper) signaling pathway.

  6. Plasma heparin cofactor II activity was independently and inversely associated with the development of cardiac remodeling, including cardiac concentric change, left atrial enlargement and left ventricular diastolic dysfunction.

  7. [REVIEW]HCII protects against vascular remodeling, including atherosclerosis

  8. potential for oversulfated disaccharides in controlling HCII-regulated thrombin (zeige F2 Antikörper) generation

  9. Aspartic acid residues 72 and 75 and tyrosine-sulfate 73 of heparin cofactor II promote

  10. role of basic amino acids of the A helix of heparin cofactor II in heparin- or dermatan sulfate-mediated thrombin (zeige F2 Antikörper) inhibition.

Mouse (Murine) serpin Peptidase Inhibitor, Clade D (Heparin Cofactor), Member 1 (SERPIND1) Interaktionspartner

  1. In this study, we demonstrate a previously unknown role for HCII in host defense

  2. HCII potentiates the activation of vascular endothelial cells and the promotion of angiogenesis in response to hindlimb ischemia via an AMPK (zeige PRKAA1 Antikörper)-eNOS (zeige NOS3 Antikörper) signaling pathway.

  3. HCII mediates the antithrombotic effect of porcine skin dermatan sulfate after injury to the carotid arterial endothelium in mice.

  4. In HCII(+/-) mice, prominent intimal hyperplasia with increased cellular proliferation was observed after tube cuff (zeige CUFF Antikörper) and wire vascular injury.

  5. HCII deficiency promotes atherogenesis and neointima formation

  6. The reactions with thrombin (zeige F2 Antikörper) or APC (zeige APC Antikörper) of recombinant alpha(1)-PI (zeige SERPINA1 Antikörper) M358R variants with or without the HCII extension were characterized electrophoretically and kinetically

  7. These results support the hypothesis that HCII interacts with dermatan sulfate in the vessel wall after disruption of the endothelium and that this interaction regulates thrombus formation in vivo.

serpin Peptidase Inhibitor, Clade D (Heparin Cofactor), Member 1 (SERPIND1) Antigen-Profil

Protein Überblick

The product encoded by this gene is a serine proteinase inhibitor which rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. The gene contains five exons and four introns. This protein shares homology with antithrombin III and other members of the alpha 1-antitrypsin superfamily. Mutations in this gene are associated with heparin cofactor II deficiency.

Genbezeichner und Symbole assoziert mit SERPIND1

  • serpin peptidase inhibitor, clade D (heparin cofactor), member 1 (SERPIND1) Antikörper
  • heparin cofactor II (serpind1) Antikörper
  • serpin peptidase inhibitor, clade D (heparin cofactor), member 1 (Serpind1) Antikörper
  • serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1 (serpind1) Antikörper
  • serine (or cysteine) peptidase inhibitor, clade D, member 1 (Serpind1) Antikörper
  • heparin cofactor II (LOC100155945) Antikörper
  • AA985900 Antikörper
  • AI303446 Antikörper
  • D22S673 Antikörper
  • HC2 Antikörper
  • Hcf2 Antikörper
  • HCII Antikörper
  • HLS2 Antikörper
  • LS2 Antikörper
  • MGC53936 Antikörper
  • rls2var1 Antikörper
  • serpind1 Antikörper
  • THPH10 Antikörper

Bezeichner auf Proteinebene für SERPIND1

heparin cofactor 2 , leuserpin 2 , protease inhibitor leuserpin-2 , serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1 , serpin D1 , heparin cofactor II , HC-II , leuserpin-2 , serine (or cysteine) peptidase inhibitor, clade D, member 1 , serine (or cysteine) proteinase inhibitor, clade D, member 1 , serpin peptidase inhibitor, clade D (heparin cofactor), member 1 , heparin cofactor 2-like , serpin peptidase inhibitor, clade D, member 1

GENE ID SPEZIES
3053 Homo sapiens
380511 Xenopus laevis
79224 Rattus norvegicus
359841 Danio rerio
696950 Macaca mulatta
100467362 Ailuropoda melanoleuca
100542650 Meleagris gallopavo
100596966 Nomascus leucogenys
100629879 Equus caballus
15160 Mus musculus
395877 Gallus gallus
100155945 Sus scrofa
100125764 Bos taurus
100009170 Oryctolagus cuniculus
100682658 Canis lupus familiaris
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